This audio program discusses a modified approach to bulimia nervosa for patients who are overweight, the role of medical comorbidity and the interaction of NSAIDs and antidepressants, the sensitivity and specificity of the proposed DSM-5 criteria for autism spectrum disorder, a meta-analysis of ADHD to clarify affected neural systems instead of individual regions, and a functional brain imaging study of patients with OCD and their siblings to identify a shared biological characteristic to serve as a marker of OCD. Articles can be viewed online at www.ajp.psychiatryonline.org.