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  • Dna Replication: Meselson & Stahl's Experiment (1958)

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    Angie Lawrence
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    Meselson & Stahl conducted an experiment in 1958 to determine which of three proposed models of DNA replication was correct. They found that the semi-conservative model, in which the parental DNA strands separate and each acts as a template for a new complementary strand, was accurate, as hybrid DNA containing both old and new strands was detected in subsequent generations, ruling out the conservative and dispersive models.

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    Dna Replication

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    Meselson & Stahl conducted an experiment in 1958 to determine which of three proposed models of DNA replication was correct. They found that the semi-conservative model, in which the parental DNA strands separate and each acts as a template for a new complementary strand, was accurate, as hybrid DNA containing both old and new strands was detected in subsequent generations, ruling out the conservative and dispersive models.

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    27 просмотров4 страницы

    Dna Replication: Meselson & Stahl's Experiment (1958)

    Загружено:

    Angie Lawrence
    Meselson & Stahl conducted an experiment in 1958 to determine which of three proposed models of DNA replication was correct. They found that the semi-conservative model, in which the parental DNA strands separate and each acts as a template for a new complementary strand, was accurate, as hybrid DNA containing both old and new strands was detected in subsequent generations, ruling out the conservative and dispersive models.

    Авторское право:

    Attribution Non-Commercial (BY-NC)
    Скачайте в формате PPTX, PDF, TXT или читайте онлайн в Scribd
    Отметить как неприемлемый контент
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    DNA REPLICATION

    Meselson & Stahls Experiment (1958)

    Experiment of Meselsohn and Stahl


    Based on Watson and Cricks double helix DNA model, three models of replication were proposed a) Conservative model- parental double helix remains and a second copy is made. b) Semi-conservative model- parental strands separate and each strand become a template for the synthesis of each new complementary strand. c) Dispersive model- both daughter strands have a mixture of the parent and the newly synthesized part.

    Meselhon and Stahl (American Biochemist) proved that replication of DNA is semiconservative. Hybrid of DNA exists in every generation. In conservative model, there will be no hybrid of DNA formed. (Therefore, this model is NOT ACCEPTED) In dispersive model, the second generation will have no 14N14N DNA. (Therefore, this model is NOT ACCEPTED) The Semi-conservative model was accepted as the correct model for DNA replication in cell.

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