Ca Penis

Primary Tumor (T)

TX T0 Tis Ta T1a Primary tumor cannot be assessed No evidence of primary tumor Carcinoma in situ Noninvasive verrucous carcinoma* Tumor invades subepithelial connective tissue without lymph vascular invasion and is not poorly differentiated (i.e., grade 34) Tumor invades subepithelial connective tissue with lymph vascular invasion or is poorly differentiated Tumor invades corpus spongiosum or cavernosum Tumor invades urethra Tumor invades other adjacent structures

T1b T2 T3 T4

Regional Lymph Nodes (N)

Clinical Stage Defi nition* cNX cN0 cN1 cN2 cN3 Regional lymph nodes cannot be assessed No palpable or visibly enlarged inguinal lymph nodes Palpable mobile unilateral inguinal lymph node Palpable mobile multiple or bilateral inguinal lymph nodes Palpable fi xed inguinal nodal mass or pelvic lymphadenopathy unilateral or bilateral

* Note: Clinical stage definition based on palpation, imaging .

Distant Metastasis (M)

M0 No distant metastasis M1 Distant metastasis*

* Note : Lymph node metastasis outside of the true pelvis in addition to visceral or bone sites.

ANATOMIC STAGE/PROGNOSTIC GROUPS

Stage 0 Tis Ta Stage I T1a Stage II T1b T2 T3 Stage IIIa T1-3 Stage IIIb T1-3 Stage IV T4 Any T Any T N0 N0 N0 N0 N0 N0 N1 N2 Any N N3 Any N M0 M0 M0 M0 M0 M0 M0 M0 M0 M0 M1

HISTOLOGIC GRADE (G)

GX G1 G2 G3 G4 Grade cannot be assessed Well differentiated Moderately differentiated Poorly differentiated Undifferentiated

HISTOPATHOLOGIC TYPE
Cell types are limited to carcinomas. Squamous cell carcinoma, not otherwise specified. Verrucous carcinoma. Papillary squamous carcinoma. Warty squamous carcinoma. Basaloid carcinoma.