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Dengue fever

"Dengue Fever" redirects here. For the band of the same name, see Dengue Fever (band). Dengue virus

A TEM micrograph showing Dengue virus virions (the cluster of dark dots near the center).

Virus classification Group: Group IV ((+)ssRNA) Family: Flaviviridae Genus: Flavivirus Species: Dengue virus

Dengue fever (pronounced /dge/ (BrE), /dgi/ (AmE)) and dengue hemorrhagic fever (DHF) are acute febrile diseases, found in the tropics and Africa, and caused by four closely related virus serotypes of the genus Flavivirus, family Flaviviridae.[1] It is also known as breakbone fever. The geographical spread includes northern Australia, Singapore, Malaysia, Taiwan, Thailand, Vietnam, Indonesia, Honduras, Costa Rica, Philippines, Pakistan, India, Bangladesh, Puerto Rico, Bolivia[2], Brazil, Guyana, Venezuela, Barbados, Trinidad and Samoa[3]. Unlike malaria, dengue is just as prevalent in the urban districts of its range as in rural areas. Each serotype is sufficiently different that there is no cross-protection and epidemics caused by multiple serotypes (hyperendemicity) can occur. Dengue is transmitted to humans by the Aedes aegypti or more rarely the Aedes albopictus mosquito, which feed during the day.[4] The WHO says some 2.5 billion people, two fifths of the world's population, are now at risk from dengue and estimates that there may be 50 million cases of dengue infection worldwide every year. The disease is now epidemic in more than 100 countries.[5]