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Therapeutic class: Antihistamine decongestant Pharmacologic class: Piperidine Use\ Indications Seasonal allergic rhinitis, Chronic idiopathic urticaria Pharmacological Effects A long-acting non-sedating antihistamine that selectively and reversibly inhibits peripheral H1 receptors. Route Adverse Reactions CNS: fatigue, drowsiness, fever, headache. EENT: otitis media. GI: nausea, dyspepsia, vomiting. GU: dysmenorrhea. Musculoskeletal: back pain. Respiratory: cough, rhinorrhea, upper respiratory tract infection. Other: viral infection. Precautions/Warnings/Contraindication Contraindicated in patients with hypersensitivity to drug Use cautiously in patients with impaired renal function. Pregnancy category: C Breast-feeding: Use cautiously Interactions: Aluminum or magnesium antacids: May decrease fexofenadine level. Erythromycin, ketoconazole: May increase fexofenadine level Dosing Adults: 60 mg P.O. b.i.d. or 180 mg P.O. once daily. Children: 15 mg (2.5 ml) P.O. b.i.d. Brand Names Tablets Telfast 60/120/180mg Fexet 40mg