ROS

http://pchd.wv.gov/topic/Antioxidants/ Generated by any metabolic processes requiring oxygen such as aerobic exercise which has been shown to generate more ROS quicker whilst anaerobic exercise induced prolonged ROS generation o By-product of mitochondria ETC Increased oxidative stress decreases physiological function - can damage muscle tissue, protein receptors, enzymes, lipid membranes due to oxidative stress ROS generated in exercise may be important signalling molecules, such as promoting muscle regeneration and therefore adequate ROS levels necessary to maintain redox allosteric buffering capacity (ABC) - enhance physical fitness and deacelerate aging, morbidity and mortality o Excessive ROS impairs redox ABC impairs physical fitness, accelerates aging, morbidity, mortality Regular exercise creates adaptations to deal with excessive ROS

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