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Hypertension; angina pectoris; MCI; acute MI Indications: prevention of migraine headaches, management of tremors, alcohol withdrawal, and anxiety. Drug Classification: Antianginal, Antiarryhthmic Mechanism of Action: Block stimulation of beta1 (myocardial) adrenergic receptors.
Hypertension; angina pectoris; MCI; acute MI Indications: prevention of migraine headaches, management of tremors, alcohol withdrawal, and anxiety. Drug Classification: Antianginal, Antiarryhthmic Mechanism of Action: Block stimulation of beta1 (myocardial) adrenergic receptors.
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Hypertension; angina pectoris; MCI; acute MI Indications: prevention of migraine headaches, management of tremors, alcohol withdrawal, and anxiety. Drug Classification: Antianginal, Antiarryhthmic Mechanism of Action: Block stimulation of beta1 (myocardial) adrenergic receptors.
Авторское право:
Attribution Non-Commercial (BY-NC)
Доступные форматы
Скачайте в формате DOC, PDF, TXT или читайте онлайн в Scribd
Generic Name: Hypertension, angina pectoris, acute MI
Indications: Hypertension; angina pectoris; MCI; PVC; unlabeled uses: prevention of migraine headaches, management of tremors, alcohol withdrawal, and anxiety. Drug Classification: Antihypertensive, Antianginal, Antiarryhthmic Mechanism of Action: Block stimulation of beta1 (myocardial) adrenergic receptors. Do not usually affect beta2 (pulmonary, vascular, uterine) receptor sites. Therapeutic Effects: decreased blood pressure and heart rate, decreased frequency of attacks of angina pectoris, slowing of ventricular response. Dosage: PO (Adults): Antianginal- 50 mg once daily initially, may be increased after 1 week to 100 mg/day may then be increased as needed. Antihypertensive- 25-50 mg once daily initially, may be increased after 2 wk to 50-100 mg once daily. MCI- 50 mg (given 10 min following last IV dose), then 50 mg 12 hr later, then 100 mg/day as a single dose or in 2 divided doses for 6-9 days or until hospital discharge. Special Precaution: Patients with renal impairment, hepatic impairment, pulmonary disease, diabetes mellitus, thyrotoxicosis, with a history of severe allergic reactions, geriatric patients, pregnant and lactating women Pregnancy Risk Category: B Adverse Reaction: CNS: fatigue, weakness, dizziness, depression, insomnia, memory loss, mental stats changes, nightmares, anxiety, nervousness, drowsiness. EENT: blurred vision, stuffy nose. Resp: bronchospasm, wheezing. CV: bradycardia, congestive heart failure, pulmonary edema, peripheral vasoconstriction, hypotension. GI: constipation, diarrhea, nausea, vomiting, liver function abnormalities. GU: impotence, decreased libido, urinary frequency. Derm: rashes Endo: hyperglycemia, hypoglycemia MS: joint pain, back pain, arthralgia Contraindications: Uncompensated congestive heart failure, pulmonary edema, cardiogenic shock, bradycardia of heart block Form: Tablets: 25 mg, 50 mg, 100 mg, Injection: 500 mcg Nursing Responsibilities: Monitor vital signs and ECG should be monitored q 5-15 min during and for several hours after parenteral administration. Administer atropine if heart rate is <40 bpm, especially if cardiac output is decreased. Monitor intake and output ratios and daily weights. Assess routinely for signs and symptoms of CHF.