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Medicina general

Tema:

PROCESELE ADAPTIV-COMPENSATORII
I.

MICROPREPARATE

35. esut de granulaie. Coloraie H-E.


Indicaii:
1. Vase cu perei subiri.
2. Celulele esutului de granulaie (macrofage, leucocite, limfocite, plasmocite,
fibroblati i a.).
36. Hipertrofia compensatorie a miocardului. Coloraie H-E.
Indicaii:
1. Cardiomiocite hipertrofiate.
2. Nuclee mrite n dimensiuni, intens colorate.
3. Cardiomiocite nemodificate.
4. Stroma fibroconjunctiv a miocardului.
38. Hiperplazia glandulo-chistic a endometrului. Coloraie H-E.
Indicaii:
1. Glande endometriale alungite, cu aspect erpuitor.
2. Glande dilatate chistic.
3. Stroma endometriului.
150. Cardioscleroz postinfarctic. Coloraie picrofuxin van Gieson
Indicaii:
1. Fascicule de esut fibroconjunctiv.
2. Cardiomiocite hipertrofiate.
II.

ELECTRONOGRAM

10. Hipertrofia regenerativ a cardiomiocitului


III.

4.
5.
90.
20.
109.
88.
123.

PREPARATE A N A T O M I C E

Hipertrofia ventriculului stng al inimii.


Hipertrofia ventriculului drept al inimii.
Hipertrofia peretelui vezicii urinare n adenom de prostat.
Atrofia brun a inimii.
Atrofia ovarului.
Hidronefroz.
Hidrocefalie

I.

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II.

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III.
4.

CELL ADAPTATION. CELL GROWTH, WOUD HEALING AND REPAIR


Microspecimen.
35. Granulation tissue.(H-E)
There are many new vessels, macropgages, lymphocytes, proliferating fibroblasts and a
loose connective tissue matrix.
36. Myocardial hypertrophy. (H-E)
Enlargement of myocardial cells and their nuclei.
38. Glandular hyperplasia of the endometrium. .(H-E)
Endometrial glands are hyperplastic and continued increase in the number of cells in each
gland has resulted in some glands showing cystic dilation. There is irregularity and
crowding of the glands and crowding of the epithelial cells lining the glands.
150. Macrofocal cardiosclerosis postinfarction. (picrofucsin van Gieson)
Connective tissue is discoloured in red-brown, but surrounded intact myocardium is
discoloured in yellow.
Macrospecimen

4.Left ventricular hypertrophy.


5.Right ventricular hypertrophy.
90. Urinary bladder wall hypertrophy in prostate adenoma.
20. Brown atrophy of the heart.
109. Atrophy of the ovary.
88. Hydronephrosis.
123. Hydrocephaly.

Electronomicrography
10. Regenerative hypertrophy of the myocardium.
Slightly hypertrophied muscle cells are characterized by the significant increase of electron
lucent cytoplasmic area containing numerous free ribosomes. As the muscle cells become
more hypertrophied, synthesis of myofilaments is frequently observed in the subsarcolemmal
and interfibrillar cytoplasmic regions rich in free ribosomes. In the markedly hypertrophied
muscle cells, the total volume of the contractile elements and the number of mitochondria are
conspicuously increased. The central sarcoplasmic core of these cells is expansively extended
and contains numerous mitochondria.