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Medicin

Tema:

TULBURRILE CIRCULAIEI SANGUINE: tromboza, embolia, hemoragia.


I.

MICROPREPARATE

4. Tromb rou recent n ven. Coloraie H-E.


Indicaii:
1. Peretele venei.
2. Trombul n lumenul vasului:
a) filamente de fibrin;
b) eritrocite hemolizate.
140. Embolia celular (canceroas) a vaselor limfatice pulmonare.
Coloraie H-E.
Indicaii:
1. Vas limfatic dilatat.
2. Embol celular (celule canceroase) n lumenul vasului limfatic.
3. Ven.
4. Alveole pulmonare.
101. Embolia microbian a vaselor renale. Coloraie H-E.
Indicaii:
1. Emboli microbieni n lumenul capilarelor glomerulare.
2. Focar de necroz n jurul embolului microbian.
3. Aglomerri de leucocite neutrofile (abces).
4. Glomerul nemodificat.
13. Hemoragii punctiforme prin diapedez n esutul cerebral. Coloraie H-E.
Indicaii:
1. Aglomerri de eritrocite (focarul hemoragic).
2. Vas sanguin.
3. esutul cerebral.
II.

PREPARATE ANATOMICE

3 -Tromboza parietal a aortei.


10 - Anevrism cardiac cronic (postinfarct) cu tromboz.
37 - Tromboembolia arterei pulmonare.
42 - Metastaze de cancer n plmn.
75 - Metastaze de melanom n ficat.
85 - Nefrit embolic purulent (abcese metastatice n rinichi).
121 - Hemoragie cerebral (hematom parenchimatos).
III.
6 Stadiile I, II, III ale formrii trombului.

ELECTRONOGRAME

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III.

6 I, II, III .

HEMODYNAMIC DISORDERS

Microspecimen
4. Thrombus in the vein. (H-E)
The vein lumen is completely occluded by thrombus attached to the vascular wall (known as
a deep vein thrombosis)
101. Purulent embolic nephritis. (H-E)
Bacterial colonies are present in the capillary lumen, glomeruls and in the surrounding zone.
The neutrophlic infiltrate is displaces in the same regions.
140. Lymphatic vessels cancerous embolism. (H-E)
Lymphatic vessels are dilated overfilled by malignant cells.
13. Diapedesis hemorrhage in the brain(H-E)
The brain tissue resemble perineural edema, and erythrocytes surrounding vascular wall.
Macrospecimen

3. Parietal thrombus in the abdominal aorta


10. Chronic cardiac aneurysm with thrombosis.
37. Thromboembolism of pulmonary artery.
85. Bacterial embolism of the glomerular capilaries
42. Cancers metastasis in lungs.
121. Cerebral hemorrhage.

Electromicrography
6. Stages I, II, III of thrombus formation
I. thrombocyte agglutination. The first figure shows the place of vascular lesion. The
mitochondria are tumefacted and homogenized, the subendothelial layer is edematous the
collagen fibers are dissociated; the unmodified thrombocytes approache the place of endothelial
lesion.
II.
The transformation of fibrinogen into fibrin.
The zone of endothelial lesion contains degranulated thrombocytes and agglomeration of fibrin
filaments, which adhere to the wall.
III.
Erythrocyte agglutination. The lumen of the vessel contains degranulated thrombocytes,
while between them there are fibrin filaments and agglutinated erhytrocytes.