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  • Elements of Protein Structure: Appendix

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    Carlos Marino Orejuela
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    This document contains information about the basic building blocks and structures of proteins. It includes: 1) Structures of the 20 standard amino acids that make up proteins. 2) Diagrams showing the patterns of hydrogen bonds in antiparallel and parallel beta-strands and beta-sheets. 3) A diagram of the alpha-helix, a common spiral secondary structure in proteins.

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    9781847558015-00727

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    This document contains information about the basic building blocks and structures of proteins. It includes: 1) Structures of the 20 standard amino acids that make up proteins. 2) Diagrams showing the patterns of hydrogen bonds in antiparallel and parallel beta-strands and beta-sheets. 3) A diagram of the alpha-helix, a common spiral secondary structure in proteins.

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    Attribution Non-Commercial (BY-NC)
    Скачайте в формате PDF, TXT или читайте онлайн в Scribd
    Отметить как неприемлемый контент
    11 просмотров4 страницы

    Elements of Protein Structure: Appendix

    Загружено:

    Carlos Marino Orejuela
    This document contains information about the basic building blocks and structures of proteins. It includes: 1) Structures of the 20 standard amino acids that make up proteins. 2) Diagrams showing the patterns of hydrogen bonds in antiparallel and parallel beta-strands and beta-sheets. 3) A diagram of the alpha-helix, a common spiral secondary structure in proteins.

    Авторское право:

    Attribution Non-Commercial (BY-NC)
    Скачайте в формате PDF, TXT или читайте онлайн в Scribd
    Отметить как неприемлемый контент
    из 4

    Downloaded by Universidad del Valle - Colombia on 18 November 2012 Published on 31 December 2007 on http://pubs.rsc.org | doi:10.

    1039/9781847558015-00727

    APPENDIX

    Elements of Protein Structure


    1 AMINO ACID STRUCTURES
    O + H3N R O R = H, glycine, Gly, G (achiral) R = CH3, alanine, Ala, A R = CH(CH3)2, valine, Val, V R = CH2CH(CH3)2, leucine, Leu, L R = CH2CH(CH3)CH2CH3, isoleucine, Ile, I (erythro configuration) R = CH2CH2CH2CH2NH3+, lysine, Lys, L R= CH2CH2CH2NHC(=NH+)NH2, arginine, Arg, R R = CH2 histidine, His, H NH
    N

    R = CH2OH, serine, Ser, S R = CHOHCH3, threonine, Thr, T


    (threo configuration).

    R = CH2SH, cysteine, Cys, C R = CH2CH2SCH3, methionine, Met, M R= CH2

    R =

    CH2

    OH

    phenylalanine, Phe, F R= CH2 N H

    tyrosine, Tyr, Y proline, Pro, P (imino-acid: complete structure shown)

    tryptophan Trp, W

    H2N

    COO

    R = CH2COOH, aspartic acid, Asp, D R = CH2CONH2, asparagine, Asn, N


    R2 N R1 H O

    R = CH2CH2COOH, Glu, E R = CH2CH2CONH2, Gln, Q

    O
    +

    H N R3

    O N H

    R4

    H N O R5

    O N H

    R6 etc

    H3N

    727

    View Online

    728 2 ELEMENTS OF PROTEIN STRUCTURE

    Appendix

    Note that the a-carbons are shown in the L-conguration.


    Downloaded by Universidad del Valle - Colombia on 18 November 2012 Published on 31 December 2007 on http://pubs.rsc.org | doi:10.1039/9781847558015-00727

    Antiparallel b-Strand
    O N H O H N N H O O H N N H O H N

    O N H O

    H N

    O N H O

    H N

    O N H O

    H N

    Antiparallel b-Sheet
    O N H O H N N H O O H N N H O H N

    O N H O

    H N

    O N H O

    H N

    O N H O

    H N

    O N H

    H N N O H

    H N N O H

    H N

    O N H O

    H N

    O N H O

    H N

    O N H O

    H N

    View Online

    Elements of Protein Structure Parallel b-Strand


    O Downloaded by Universidad del Valle - Colombia on 18 November 2012 Published on 31 December 2007 on http://pubs.rsc.org | doi:10.1039/9781847558015-00727 N H O N H O O H N N H O O H N N H O H N N H O O O H N N H O H N O H N

    729

    Parallel b sheet
    O N H O N H O O H N O N H O H N O N H O H N O N H O H N O N H O H N H N

    O N H O N H O O

    H N

    O N H O

    H N

    O N H O

    H N

    H N

    O N H O

    H N

    O N H O

    H N

    Downloaded by Universidad del Valle - Colombia on 18 November 2012 Published on 31 December 2007 on http://pubs.rsc.org | doi:10.1039/9781847558015-00727

    730 Appendix
    View Online

    a-Helix

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