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Endocrine System Embryo & Histology

A Reviewer for MicroAnatomy Practicals

Dorsal Pancreas
Anlage: Endoderm Fate: Pancreas (head part) Secretion: (islets of langerhans) A cells - glucagon B cells - insulin D cells - somatostatin G cells - gastrin F cells pancreatic polypeptide

Rathkes pouch

Germ Layer: Ectoderm Anlage: Stomodeum Fate: Anterior Pituitary gland (adenohypophysis)

Ultimobrachial body
Germ layer: Endoderm Fate: parafollicular cells Secretion: calcitonin

Thyroid gland

Germ layer: Endoderm Anlage: primordial thyroid gland Fate: Thyroid gland Secretion: Thyroid hormones (T3&T4)

Undifferentiated Gonad
Male: Germ layer: Mesoderm Fate: Testis *leydig cells - testosterone

Female: Germ layer: Mesoderm Fate: Ovaries *theca interna estrogen *granulosa cells - progesterone

Pancreas: Islets of Langerhans


Organ: Pancreas Secretion: (islets of langerhans) A cells - glucagon B cells - insulin D cells - somatostatin G cells - gastrin F cells pancreatic polypeptide

Adrenal gland
Layer: Zona glomerulosa Secretion: mineralocorticoid (aldosterone) Adrenal Cortex Layer: Zona fasciculata Secretion: glucocorticoids (corticosterone, cortisone, cortisol)

Adrenal medulla

Zona reticularis Secretion: Androgen (sex hormones)

Parenchema: Chromaffin cells

Adrenal Gland
Adrenal medulla Parenchema: Chromaffin cells Secretion: Norepinephrine & Epinephrine

Medullary veins

Pineal gland
Germ layer: Ectoderm Parenchema: pinealocytes Secretion: Melatonin

Brain sands or acervulus (concretions of calcium carbonate and calcium phosphate)

Anterior pituitary gland (Pars distalis)

Anlage: Stomodeum / Rathkes pouch Germ layer: ectoderm Secretion: FSH, LH, GH, PRL, ACTH, TSH Parenchema: Chromophils

Anterior Pituitary gland (pars tuberalis)

Anlage: Stomodeum / Rathkes pouch Germ layer: ectoderm Secretion: none

Ant. Pituitary gland (Pars intermedia)

Rathkes cyct

Pars nervosa

Anlage: Stomodeum / Rathkes pouch Germ layer: ectoderm Secretion: POMC

Posterior Pituitary gland (Pars nervosa)

Anlage: Infundibulum Germ layer: ectoderm Secretion: oxytocin and ADH Parenchema: pituicytes

Placenta
Chorionic Villi

Specific structure: Syncitiotrophoblast Secretion: human chorionic gonadotrophin (Hcg)

Ovary

Specific structure: theca interna Secretion: Estrogen

Specific structure: zona granulosa cells Secretion: progesterone

Testis
Germ Layer: Mesoderm Structure: Leydig cells Secretion: testosterone

Specific structure: sertoli cells Secretion: inhibin

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