Contamination of Drugs In Pakistan, more than 200 people died and around 1000 became seriously ill after

taking contaminated cardiac medicines. The patients showed signs of bleeding from mouth and gastrointestinal tract, strange dark marks on skin and extremely low levels of white blood cells and platelets. On 31 January, the United Kingdom Medicines and Healthcare Products Regulatory Agency announced that it had identified the contaminant. Large quantities of antiparasitic drug pyrimethamine were discovered in a batch of cardiovascular medication called Isotab. The drug had been manufactured by Efroze, a wellestablished manufacturer in Pakistan that makes both cardiovascular and antimalarial medications at its facility in Karachi.
World Health Organization visited the manufacturing site of Isotab where it was established that a 25kg drum of pyrimethamine had gone missing and had accidently been mixed into a batch of the cardiac medicine.