is a method of achieving action potential when the neurotransmitter does not generate enough V change

to achieve the

EPSP THRESHOLD of 25mV to produce an ACTION POTENTIAL

1. SPATIAL SUMMATION

2. TEMPORAL

SUMMATION

2 OR MORE

SEPARATE INPUTS ARRIVE SIMULTANEOUSLY ON THE POST-SYNAPTIC NEURON

 2 OR MORE

ACTION POTENTIALS APPLIED FROM A SINGLE NEURON IN RAPID SUCCESSION

enzymes in the synapse that

serve to chemically alter the neurotransmitter, making it nonfunctional

ie. ACETYLCHOLINESTERASE

REABSORPTION OF A

NEUROTRANSMITTER FOR RECYCLING & REGULATION OF THE LEVEL OF NEUROTRANSMITTER PRESENT

MAKE USE OF

TRANSPORTERS, WHICH IS SODIUM DEPENDENT

ie. choline

REDUCTION OF THE

NUMBER OF RECEPTORS TO ALTER ITS SENSITIVITY TO THE NEUROTRANSMITTER