HOMOLOGOUS SERA

INCLUDES IMMUNOGLOBIN AND HYPERIMMUNE SERA CONTAINS SPECIFIC ANTIBODIES

SOURCE: POOLED PLASMA OF ADULT DONORS

CONDITIONS: FREE FROM HEPA B ANTIGEN : FREE FROM ANTIBODIES TO HIV

PROCESSING STEPS:
1. FRACTIONAL PRECIPITATION
2. CONTROL OF pH AND IONIC STRENGTH 3. FURTHER PURIFICATION

EXCEPTIONS: VARICELLA-ZOSTER IMMUNOGLOBINS (VZIGs)

HOMOLOGOUS SERA ARE ADMINISTERED INTRAMASCULAR INJECTION

HOWEVER, SOME ARE ADMINISTERED INTRAVENOUSLY

SERA HAVE THE GREATEST VALUE FOR THE

TREATMENT OF ACUTE DISEASES.

HOWEVER, THESE SERA LASTS ONLY FOR A FEW

WEEKS.

HETEROLOGOUS SERA PREPARED BY THE IMMUNIZATION OF HORSES AGAINST SPECIFIC IMMUNOGEN. EXAMPLES: TOXIN AND VENOM PROCEDURE: 1. HARVEST THE PLASMA

2. SEPARATE THE IMMUNOLOGICALLY ACTIVE AND

INACTIVE COMPONENTS USING FRACTIONAL PRECIPITATION 3. THE ACTIVE COMPONENT IS TREATED WITH PEPSIN 4. THROUGH DIALYSIS AND CETRIFUGATION, THE ACTIVE COMPONENT IS RECOVERED

HETEROLOGOUS SERA ARE CATEGORIZED TO ANTITOXINS AND ANTIVENINS.

CATEGORY

PRODUCED BY

ANTITOXINS

INCREASE DOSAGE OF TOXOIDS AND EXOTOXINS OF HORSES

ANTIVENINS

INOCULATING THE HORSES WITH THE SPECIFIC VENOM

EXAMPLES OF OFFICIAL BIOLOGIC PRODUCTS

I. VACCINES AND VACCINES COMBINATION

ANTHARAX ABSORBED

EXAMPLES OF OFFICIAL BIOLOGIC PRODUCTS

I. VACCINES AND VACCINES COMBINATION

BCG

EXAMPLES OF OFFICIAL BIOLOGIC PRODUCTS

I. VACCINES AND VACCINES COMBINATION

HEPA B

EXAMPLES OF OFFICIAL BIOLOGIC PRODUCTS

I. VACCINES AND VACCINES COMBINATION

HUMAN PAPILLOMA VIRUS VACCINE

EXAMPLES OF OFFICIAL BIOLOGIC PRODUCTS

I. VACCINES AND VACCINES COMBINATION

INFLUENZA

EXAMPLES OF OFFICIAL BIOLOGIC PRODUCTS

I. TOXOIDS TETANUS

EXAMPLES OF OFFICIAL BIOLOGIC PRODUCTS

I. VACCINES AND VACCINES COMBINATION

TETANUS, ADSORBED

EXAMPLES OF OFFICIAL BIOLOGIC PRODUCTS

I. VACCINES AND VACCINES COMBINATION

TETANUS, DIPHTHERIA ADSORBED FOR ADULT USE

EXAMPLES OF OFFICIAL BIOLOGIC PRODUCTS

I. VACCINES AND VACCINES COMBINATION
ANTITOXINS

BOTULISM

EXAMPLES OF OFFICIAL BIOLOGIC PRODUCTS

I. VACCINES AND VACCINES COMBINATION
IMMUNE SERA
IMMUNOGLOBIN IM

EXAMPLES OF OFFICIAL BIOLOGIC PRODUCTS

I. VACCINES AND VACCINES COMBINATION
MISCELLANEOUS BIOLOGIC PRODUCT
ANTIVENIN POLYVALENT

EXAMPLES OF OFFICIAL BIOLOGIC PRODUCTS

I. VACCINES AND VACCINES COMBINATION