Brand Name: Cozaar

Generic Name: Losartan Potassium

Indications: Hypetension, Nephepatically in type 2 daibetic patients, to reduce risk of
CVA in patients with hypertension and left ventricular hypertrophy
Drug Classification: Anti-hypertensives
Mechanism of Action: Inhibits vasoconstrictive and aldosterone-secreting action of
angiotensin II by blocking angiotensin II receptor on the surface of vascular
smooth muscle and other tissue cells.
Dosage: For Hypertension: Adults- Initially 25-50mg PO daily, For Nephropahty:
Adults-50mg PO od.
Special Precaution: Impaired renal or hepatic function
Pregnancy Risk: C; D in 2nd and 3rd trimesters
Adverse Reaction: CNS-dizziness, asthenia, fatigue, headache, insomia. CV-edema,
chest pain. EENT-nasal congestion, sinusitis, pharyngitis, sinus disorder. GI-Abdominal
pain, nausea, diarrhea, dyspepsia. Musculoskeletal-muscle cramps, myalgia, back or leg
pain. Respiratory-cough, upper respiratory infection.
Contraindications: Patients hypersensitive to drug, breast-feeding is not recommended,
causes fetal and neonatal morbidity and death when administered in the 2nd and 3rd
trimester of pregnancy.
Form: Tablet
Nursing Responsibilities:
 Monitor patients BP.
 Monitor patients who are also taking diuretics for symptomatic hypotension.
 Assessmpatients renal function
 Tell patient to avoid salt substitutes