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Dr. Crandalls
exam. I interview my patient about his or her work environment, trying to determine how much stress the person may be under. Then I order a full lab work-up: Cholesterol counts, triglycerides, markers related to renal and thyroid function, homocysteine, C-reactive protein the works. Patients generally take a stress test, either a regular EKG stress test (walking on a treadmill) or a nuclear stress test, in which radioisotopes are introduced into their bloodstream. A nuclear test allows us to see the blood flow as well as track the hearts rhythm. The amount of time a patient can spend on a treadmill is remarkably predictive of their nearterm prognosis. If a patient can spend 10 minutes on a treadmill thats being gradually elevated, the incidence of a fatal myocardial infarction (heart attack) over the next year is likely close to zero. We do an echocardiogram to establish the size of the heart and check for murmurs. We perform a
In This Issue...
Hitting Initial Targets.............................................. 2 Diet and Exercise, Avoiding Drugs.......................... 3 Case Study: Eternal Vigilance ................................. 4 Can You Change Your Life?.................................... 5 Better Sex, Better Heart Health . ............................ 6 The Ultimate Change.............................................. 7 Ask Dr. Crandall..................................................... 8
carotid ultrasound to look at the thickness of the artery and specifically the intima the lining of the artery. The carotid artery is often a window to what is happening in the heart and the rest of the circulatory system; the thicker the carotid artery, the greater the underlying disease. Why am I telling you all this? Because its the start of the reeducation process, the first and most important step in the battle against heart disease. You will be far more prone to listen to the doctors advice if the tests he cites are meaningful to you. Your doctor should guide you along this path by seeing you regularly. I want to see my patients once a month for the first six months, then once every two months for the next six months, then three times the following year. If your doctor thinks such a schedule is overkill, consider changing physicians. See me in six months doesnt work in the battle against heart disease. Believe me. Counseling is imperative because a cardiac patient goes through an often predictable cycle. At first, he is willing to do just about anything. Over time, though, the patients resistance to change inevitably increases. Unless your doctor is in front of you on a regular basis, your odds of beating heart disease are poor.
Total cholesterol count under 150 HDL cholesterol should be greater than 45 LDL cholesterol should be less than 70 The particle number for LDL should be less than 1,000 LDL should be described as Pattern A, meaning your LDL cholesterol particles are large and buoyant Triglyceride count less than 150 A fasting glucose, serum (sugar) count between 65 and 99 Body mass index (BMI), the percentage of body weight that comes from fat, should be under 25 Thyroid, C-reactive protein, and homocysteine all within the normal range I try as soon as possible to start using natural substances. Niacin (vitamin B3) is terrific at lowering LDL and boosting HDL. Most significantly, it changes dense, small LDL particles into larger, more buoyant particles that do not embed as easily in arterial lining. Niacin has the unhappy side effect of causing flushing an uncomfortable rush of blood to the face. This feels like breaking out in a sudden heat rash: hot and prickly. For this reason, the patient needs to start with a low dose of niacin, 250 milligrams, and build up the amount slowly. The dosage should be increased by 250 milligrams every three months. Its best to take the dose at night with aspirin, which mitigates the flushing. If you are asleep and experience minor flushing you probably wont even wake up. It usually takes a patient one to two years to arrive at the maximum dosage that can be tolerated. Ideally, Id like to see a patient take between 1,500 and 3,000 milligrams daily, but few can reach this level. Any dosage the patient tolerates is a plus.
Dr. Crandalls Heart Health Report is a publication of Newsmax Media, Inc., and Newsmax.com. It is published monthly at a charge of $54.00 per year and is offered online and in print through Newsmax.com. Our editorial ofces are located at 560 Village Blvd., Ste. 120, West Palm Beach, FL 33409. The owner, publisher, and editor are not responsible for errors and omissions. Rights of reproduction and distribution of this newsletter are reserved. Any unauthorized reproduction or distribution of information contained herein, including storage in retrieval systems or posting on the Internet, is expressly forbidden without the consent of Newsmax Media. For permission, contact the publisher at : PO Box 20989, West Palm Beach, FL 33416. CEO Christopher Ruddy Health Publisher Travis Davis Author Chauncey Crandall, M.D. Contributing Editor Harold Fickett Production/Art Director Elizabeth Dole To contact Dr. Crandalls Heart Health Report send e-mail to: askdrcrandall@newsmax.com. Subscription/Customer Service contact 1-800-485-4350 or heartreport@newsmax.com. Send e-mail address changes to heartreport@newsmax.com. 2010 Newsmax Media, all rights reserved. Please note that this advice is generic and not specic to any individual. You should consult with your doctor before undertaking any medical or nutritional course of action.
May 2010
Fish oils (omega- 3 and 6 fatty acids) can provide exceptional benefits to patients who have trouble controlling their triglycerides (another form of fat in the blood). Fish such as salmon, trout, mackerel, and sardines contain large amounts of these fatty acids. For those who want to make sure they get enough fish oil by taking supplements, I recommend 2 grams daily. Some doctors recommend as much as 4 grams. Fish oils are commonly sold in IU units, so youll have to consult the label or ask your provider how many IU units translate into 2 grams. (IU units are based on effect, not weight, and so the number of units in a substance varies with the substance.) Then there are common foods and substances that help reduce cholesterol. Its important to realize, though, that each of these has only a marginal effect. They have nothing like the potency of, say, statin drugs. They should be used only once the patients cholesterol is well under control. Oat bran and oatmeal are good. I start each day with a bowl of cooked oat bran with blueberries. I put a little maple syrup, nutmeg, and cinnamon on top. I prefer this concoction cold and will boil up a batch and save it in the refrigerator for the next two to three days. (If you find this peculiar, so does my wife.) Oat bran and oatmeal work like this: They both bind cholesterol in the small intestine, causing the system to eliminate it rather than reabsorb it into the liver. Red rice yeast has effects similar to statins. Its hard to know, though, whether you are getting the real thing or a counterfeit. Some Chinese producers were found to be heightening its statin-like effects by adding a statin into the mix. Be sure you are buying from a reliable provider. Garlic and vitamin C supplementation also can provide some minor benefit. When first treating my patients for heart disease, however, Im most concerned with getting their cholesterol and blood pressure to target as fast as possible. Although my goal is to get a patient to supplements soon, and eventually off of even
May 2010
supplements, in most cases I start off by prescribing a statin drug, starting with a low dose and increasing it as needed as we track the results of subsequent blood tests. Statins are the most effective means of reducing LDL cholesterol. Some, such as Crestor, also elevate the good HDL cholesterol. They are also vasodilators, meaning they expand the arteries and improve blood flow. Statins, like every medication, carry risks. Im concerned most immediately that my patients dont experience any muscle breakdown from the CPK enzyme and accompanying muscle and joint pain. Usually, these negative side effects can be remedied by switching to another statin. Theres good evidence that a supplement called CoQ10, taken along with a statin, helps alleviate cramping. The biggest worry with statins, however, is that they can impair liver function. Thats unusual, though. (Next months issue will be about statins, and we will get into this in much more detail then.) Standard tests for liver function are needed, of course.
him off statins and substitute natural supplements, including niacin and sh oil. His plant-based diet gave his body the chance to cleanse itself of extra fat, not only around the patients waist but within his arteries as well. His improved blood ow allowed him to exercise more actively, which kept improving his blood ow. The engineer even became more mentally sharp and better able to contribute to his increasingly successful business. The fact is, a lot of the mental drop-off that we often attribute to growing older is actually the effect of growing heavier and more sedentary. Both the engineer and his wife looked like they were 25 years younger. They kept to their new way of living for four years.
Dangerous Times
The next year, though, they didnt come in for their follow-up appointments. Even I tended to dismiss this as not being terribly signicant, as I did not want to imagine my best patient ceasing to be a shining example. The following year the engineer and his wife did nd their way back to my ofce, and the engineer was back in sorry shape. What had happened to them? Oddly enough, success happened. Let me explain: The troubled times of the last decade, with global terrorism on the upswing, were driving the engineers business to ever greater heights. Meanwhile, the couples children had grown up and left the house. As empty nesters, the couple felt less need to be accountable. His achievements had tricked the engineer into believing that he was immune to heart disease. He fell back into his old ways, drinking a six-pack a night. He was honest about it, though. The engineer simply said he had failed and needed to get back on the program. I didnt let him off that lightly, though. I pointed out that he was in the business of helping governments recognize terrorism in every far-ung corner of the world. Why couldnt he have recognized the terror that was as close as his next can of beer? It is said that the price of freedom is eternal vigilance. The price of freedom from heart disease is no less. Once you begin the program, stay on track!
May 2010
blood pressure. I often wait three months, until a patients hypertension is no longer acute, to see how much improvement can be brought about through diet and exercise. Losing 10 pounds works as well as or better than a typical dose of a blood pressure medication, for instance. If the patients blood pressure demands it, though, I usually begin slowly with a once-aday medication, typically an ACE inhibitor such as Lisinopril. Over time I may add two more, a beta blocker and a medication from the class of drugs called ARBs. There are other types of blood pressure medications to consider as well. Along with these prescriptions, I ask the patient to cut out stimulants such as caffeine and alcohol, and to reduce salt intake drastically. Cutting the amount of salt consumed demands more than putting down the shaker. Processed foods are loaded with salt. Freshly cooked meals from a diet thats plant-based are a must. For patients who have had cardiac events or have been diagnosed with underlying heart disease, I prescribe a radical six-month, plantbased, oil-free diet. This diet concentrates on eating whole grains, potatoes and other starches, legumes (beans) vegetables, and fruit. Ill expand on the ideal diet in future newsletters. The patient and his or her spouse must prepare to implement it by studying what you can eat, clearing the house of junk food, and restocking the larder with plenty of good food. Its important that you not become too hungry, that you eat good but modest meals three times a day, and choose only healthy snacks. Most patients find my plant-based diet the toughest part to accept of the seven-step plan to reverse heart disease. It works, though. And you have to adhere to it strictly for only six months. Isnt your life worth a six-month change in your eating pattern? Ideally, Id like my patients to restrict themselves to 1,800 calories per day. A plant-based diet makes this easy, as you can eat a lot of food if you cut out dairy, sugar, and oils, which have high calorie counts. As for exercise, I want my patients to
walk, swim, or cycle for one hour a day. Ballroom dancing and tennis are excellent, too. I stress walking more than anything else because beyond age 50 men and women can have trouble maintaining their balance on a bicycle, and jogging or running is hard on the knees, spine, and back. Walking is something most can do for a lifetime. The walking can be varied according to what I call the God formula. Think of how we lived before the industrial era before four wheels came to replace our two feet. Men went out hunting, which was mostly walking. During the hunt, they ran in bursts to close on their prey or jogged at a steady pace while tracking a wounded animal. Then they walked home. We were not created to run hard mile after mile like marathoners. We were created to walk and then run and then walk. I dont want to deny you the exhilaration of running or jogging if you are able; Id just advise you to do this during stretches of a good long walk. When you think about it, the God formula applies equally to my plant-based diet: Throughout human history, most of our ancestors ate a diet that was plant-based. The consumption of meat would have been reserved for times of feasting and it would have been part of a life that was active from sunup to sundown.
May 2010
Quick Takes
Better Sex May Mean a Better Heart
Men who have sex at least twice a week are up to 45 percent less likely to have heart disease than men who have sex once a month or less. So says a study conducted on 1,000 men since 1987 by the New England Research Institute. The study tracked the sexual activity of men between ages 40 and 70, checking them at regular points over a 16-year period for both sexual activity and signs of heart disease. Taking into account risk factors such as age, weight, blood pressure and cholesterol levels, the results showed that the benets of sex could be due to its physical as well as emotional effects. It seems that men with the desire for frequent sexual activity and who are able to engage in it are likely to be healthier. One reason for this might be that men who have frequent sex are more likely to be in a supportive relationship, which improves health through stress reduction. Sex also has a physical activity component that might improve heart health. An earlier study at the National Cancer Institute also showed that men who had sex at least ve times a week were much less likely to get prostate cancer. And a study at Wilkes University in Pennsylvania showed that sex once or twice a week in winter can boost the immune system, reducing the chances of catching colds and u. plenty of time to get healthy before you get into the high-risk years. In other words, stopping smoking, eating right, losing weight, and exercising now can prevent heart disease as you age. Early screening, including blood pressure, pulse, waist circumference, and body mass index (BMI) the amount of weight attributable to fat should be checked every two years. Some other factors to consider: Women over 35 who use contraceptive birth control should consider stopping if they have high cholesterol, uncontrolled high blood pressure, a BMI over 30, or a smoking habit. Older oral contraceptives with high doses of estrogen have been shown to create risk factors for heart disease and to increase the chance of blood clots. Women with histories of irregular menstrual cycles at age 35 have a 50 percent greater chance of eventually having a heart attack, possibly because erratic cycles are frequently linked with obesity. Medication and weight loss can get symptoms under control and should reduce heart risk later in life. It is believed that the correlation between ARB use and decreases in dementia stems from increased blood ow to the brain. The effectiveness of these drugs was even greater among men who used them in conjunction with another blood-pressure treatment called angiotensin converting enzyme (ACE) inhibitors.
change, often called male menopause. In both cases, hormones decline: estrogen in women and testosterone in men. (Testosterone also declines in women, and the declines have an impact on libido in both sexes.) As a result of these hormonal changes, the fuel that drives the engine of cholesterol control runs low. Muscle mass decreases. These changes often lead to weight gain. Additional pounds and our sedentary lifestyle exacerbate muscle loss a vicious cycle sets in. And, people over 50 simply cannot bounce back from overwork or stressful situations as well as younger folks. You have to begin to adjust your schedule because you cannot go at the same pace you once did. When I played middle linebacker, for instance, I could pick up the front end of a Volkswagen. At 55, I cannot, and I dont expect to for the rest of my life. Its likely youll feel nervous and anxious more. Think of a 14-year-old standing over a three-foot putt to make par. Now imagine yourself in the same situation. Who would you bet on? Even if you are ready to admit you dont suffer from the delusion of invincibility you once had, you might find it hard to think of the ways your schedule might be changed to cut stress. Recently, President Clinton had two stents inserted. His staff spoke of trimming his schedule around the edges. Hed better do more than that. Once again, I find spouses are my greatest allies in helping their mates implement stress reduction. I often ask couples to go away for a long weekend together and make a list of the ways the patient can alter his (or her) lifestyle. A spouse can usually point out how late the patient stays at work, for example. Spouses can also be more candid about a patients drinking and smoking habits. In my own case, I had to give up working until 11:30 p.m. every day. I had to come home at dinnertime in order to have a decent, modest meal, instead of waiting until I was famished then vacuuming up cafeteria food. Working shorter hours decreased my income, but that was a necessary adjustment as part of my recovery program. You must realize that you need a balance in
May 2010
your life between work and recreation. You need to draw closer to your family members and spend more time talking to them. Talking to ones spouse is my No. 1 stress reducer and, for most, the easiest to implement. Take time dedicated time to pray. Concentrate on all the things for which you are grateful. It is impossible to feel stressed when you are feeling grateful. I mean literally impossible: The two emotions are polar opposites. Stressful events inevitably will come to every person and household. But if you modify your schedule, youll be able to handle it better. I find, for instance, that I need to start the day with exercise. The rest of the day is beyond my control and once it starts exercise time seems to go out the window. Some people are at a place in life where they can take a long lunch break. Instead of going out to eat, I recommend that they walk.
exercise actually increases the brains capacity to experience pleasure. Finally, get to bed on time. Those who do not get enough sleep are much more likely to be overweight. Research has shown that good shut-eye prevents the disruption of some of the hormones that control appetite.
A friend told me he takes resveratrol as part of keeping his heart healthy. I understand it has antioxidants, like in red wine. Is resveratrol, or red wine for that matter, helpful in preventing heart disease, as my friend claims? Max S., Decatur, Illinois
A glass of red wine per day is recommended by the American Heart Association. It helps boost the levels of good cholesterol (HDL). It also helps reduce blood clot formation and helps prevent artery damage caused by high levels of low-density lipoprotein cholesterol (LDL). Red wine also contains antioxidants called polyphenols that help protect the lining of blood vessels in your heart. Resveratrol is an antioxidant found in red wine as well as in other foods, including grapes, peanuts, blueberries, and cranberries. Research on resveratrol indicates that it could be linked to a reduced risk of inflammation and blood clotting, both of which could lead to heart disease. If you presently drink red wine in moderation, you may be receiving some health benefits, but remember that alcohol intake also has a lot of drawbacks, including increased cancer risk.