Nama Kelompok : 1. Annisa Luthfritayanti 2. Eko Nur Setiawan 3. Fila Del ia !. Kartika Damasanti "amonto #. Kusnul Nurhi$ayah %.

"eilisa Athiyah &. Sattrio Destrianto ' (. Siti )asanah ADVERSE REACTIONS AND GASTROINTESTINAL TRACT Pendarahan GI *+at : non streroi$al anti,inflammatory $an antiplatelet-anti.oa/ulants Angka Penyebab : 1. 01 +lee$in/ An/ka penye+a+ : /astri. erosions 2a+out !3.2456 .om+ination of /astri. ul.er an$ /astri. erosions 21%.1456 /astri. ul.er 21#.3456 $uo$enal ul.er 213.(456 normal 213.(45 an$ $uo$enal erosions 21.145. *+at : aspirin6 a.eno.umarol6 .lopi$o/rel6 .om+ination of aspirin an$ .lopi$o/rel 2. Diarrhea An/ka penye+a+ : 1t7s estimate$ that $iarrhoea a..ounts for the &4 of AD8s. *+at : metformin6 some .hemotherapies6 anti+ioti.s6 mainly .la ulani.6 .lin$ami.in6 immunosuppressant6 anti+ioti.s6 hipomotility $ru/s6 steroi$s6 proton pump inhi+itors +e.ause of the possi+ility of 9lostri$ium $iffi.ile $iarrhea. 3. 9onstipation an$ hypomotility An/ka penye+a+ : 1n the settin/ of 19: patients hipomotility an$ .onstipation appears in #3,(3 4 *+at : Anti.holiner/i. $ru/s !. )ypomotility An/ka penye+a+ : , *+at : E;o/enous .athe.olamines6 opioi$s #. 9onstipation An/ka penye+a+ : ,

 *+at : *pioi$s6 antihistamines6 .al.ium .hannel +lo.kers6 $iureti.s6 tri.y.li. anti$epressants. %. 'an.reatitis An/ka penye+a+ : Dru/ in$u.e$ pan.reatitis a..ounts for 3.1,24 *+at : A9E inhi+itors6 A8A,26 loop $iureti.s an$ thia<i$es6 statins6 +e<afi+rate6 some anti+ioti.s6 pentami$ine6 a<athioprine6 mer.aptopurine6 aminosali.ylates6 anti.on ulsi antsan$ antipsy.hoti.s6 estro/ens6 .ar+ima<ole6 some antineoplasti.s6 .o$eine6 sulin$a..