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Ciencia Análisis de homogeneidad a los datos climatológicos'
Malariais a public health problem worldwide due to their morbidity and mortality. It is a
leading parasite disease in the tropics and subtropics including Latin America. Most cases
of malaria are due to Plasmodium vivax y Plasmodium falciparum. Current treatments are
becoming less effective due to the development of resistance by the protozoan; therefore it
is necessary to search for new effective therapeutic alternatives. In this studyweevaluated
the biocide activity of threealkamidesandborneolesterfromH. longipesroots against
P.falciparumin vitro.TheN-isobutyl-2E, 6Z, 8Edecatrienamide showedbiocide activity at
72.39μM, while its partially reducedmoleculeN-isobutyl-2Edecamonoenamidewas at
133.3μM.For theN-isobutyl-2Z-monoen-8, 10-diinundecamide the biocide activity was at
17.02μMand2E,6Z,8Ebornyldecatrienoatewasat52.98μM.The resultssuggestthatalkamides
of H. longipesA.BlakeGrayhavebiocide activity, which is influenced bythe presence ofNisobutyl
substituent, double bondsat 6Z, 8Epositionsand long chain.
Ciencia Análisis de homogeneidad a los datos climatológicos'
Malariais a public health problem worldwide due to their morbidity and mortality. It is a
leading parasite disease in the tro…