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Deep vein thrombosis (DVT) is a condition where a blood clot forms in the deep veins of the body, most commonly in the legs. It affects about 80 out of every 100,000 people per year in the United States. Risk factors include prolonged inactivity, surgery, travel, genetic factors, pregnancy, oral contraceptives, and cancer. Symptoms can include pain, swelling, redness, and discoloration in the legs. Diagnosis involves blood tests, ultrasound imaging, and MRI. Without treatment, DVT can cause pulmonary embolism, long-term leg damage, and other complications.
Deep vein thrombosis (DVT) is a condition where a blood clot forms in the deep veins of the body, most commonly in the legs. It affects about 80 out of every 100,000 people per year in the United States. Risk factors include prolonged inactivity, surgery, travel, genetic factors, pregnancy, oral contraceptives, and cancer. Symptoms can include pain, swelling, redness, and discoloration in the legs. Diagnosis involves blood tests, ultrasound imaging, and MRI. Without treatment, DVT can cause pulmonary embolism, long-term leg damage, and other complications.
Deep vein thrombosis (DVT) is a condition where a blood clot forms in the deep veins of the body, most commonly in the legs. It affects about 80 out of every 100,000 people per year in the United States. Risk factors include prolonged inactivity, surgery, travel, genetic factors, pregnancy, oral contraceptives, and cancer. Symptoms can include pain, swelling, redness, and discoloration in the legs. Diagnosis involves blood tests, ultrasound imaging, and MRI. Without treatment, DVT can cause pulmonary embolism, long-term leg damage, and other complications.
Definition Condition in which a blood clot (thrombus) forms in or more of the deep veins that returns the blood from heart. Most commonly in veins of calves, femoral, popliteal, and iliac vessels
Epidemiology - 80/100 000 cases/year - Up to 2 million people in US suffer from DVT/year - Out of 200 000 people with DVT, 50 000 will be complicated by pulmonary embolism
Etiology - Prolonged inactivity/stasis of blood flow - Post surgery (vascular damage) - Long travel hour - Hyperviscosity syndrome
Risk factor - Antithrombin III deficiency - Protein C/S deficiency - Smoking - Pregnancy and oral contraceptive use - A pacemaker catheter that has been passed through the vein in the groin - Bedrest - Family history of blood clots - Fracture is the pelvis;legs - Giving birth within the last 6 months - Obesity - Recent surgery (most commonly hip, knee, or female pelvic surgery) - Too many blood cells being made by the bone marrow, causing the blood to be thicker and slower than normal
Clinical Manifestation - Asymptomatic - Symptomatic o Pain during dorsiflexion of foot (Homans sign) o Tenderness, erythema, edema of lower limb o Intermittent claudication o Cyanosis/painful blue inflammation (phlegmasia cerulea dolens)
Diagnosis - Serum D-Dimer test: (+) not specific - Coagulation profile: evaluate hypercoagulable state, prolonged PT/APTT doesnt imply lower risk of DVT - USG: venous compression duplex, 95% sensitivity for symptomatic DVT - MRI