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Inflammation is the reaction of vascularizd living tissue to local injury. It is evoked by microbial infections,
physical agents, chemicals necrotic tissue and immunologic reactions. Inflammation and repair may be potentially
harmful.
Exudation:
The escape of fluid, proteins and blood cells from vascular system into the interistial tissue or body cavities.
Exudates:
It is an inflammatory extra vascular fluid that has a high protein concentration much cellular debris and high
specific gravity about (1.020).
Transudate:
It is a non inflammatory fluid with low protein content and specific gravity less than 1.012. It is essentially and
ultra filtrate of blood plasma and results from by drostatic imbalance.
Edema:
It is an excess or abnormal accumulation of fluid in the interistial tissue or serous cavities. It can be either
Exudate or Transudate.
Pus:
It is a purulent inflammatory exudate rich in leukocytes and cell debris.
Function:
1. Dilution of irritant.
2. Transport of protective antibodies.
3. Transport of micro-organisms and toxins.
4. Fibrin formation.
5. Transport of nutrient to the cell thus helping regeneration.
Systemic effect of inflammation:
1. Fever
2. Sleepiness, poor appetite and increased muscle protein catabolism.
3. Blood changes.
a. Leukocytosis.
b. Neutrophilia.
. E leukocytosis
. Lymphocytosis.
c. Leucopenia
d. Leaku reaction.
. Thrombocytopenia
. E.S.R.
. Anemia.