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Jon Brown
Leonard Bagwala
WHAT IS EBOLA
- Ebola hemorrhagic fever:
Named after a river in the Congo
where it was first found
- Often-fatal
-Family: Filoviridae
-Order: Mononegavirales
-5 distinct sub-species
-Cote dIvorie(Ivory Coast)
ebolavirus
-Reston ebolavirus
-Sudan ebolavirus
-Zaire ebloavirus
-Bundibugyo ebolavirus
- Characteristics of Filoviruses:
- Filamentous form with a uniform
diameter of approximately 80 nm but
display great variation in length.
- Nonsegmented negative-stranded
RNA genome containing 7 structural
and regulatory genes.
Zoonotic (animal-borne)
Four of the 5 subtypes occur in an animal host native to
Africa 1 occurs in Philippine monkeys .
Origination: Africa...The virus is not known to be native to
other continents, such as North America.
Modes of Infection
Early Symptoms
During the incubation period, (2 to 21
days),
symptoms include:
Arthritic pain
Backache (low-back pain)
Chills
Diarrhea
Fatigue
Fever
Headache
Malaise (general feeling of being unwell)
Nausea
Sore throat
Vomiting
Late Symptoms
Late symptoms include:
How it works
Tetherin: A human cellular protein
which inhibits retrovirus infection
by preventing the diffusion of virus
particles after budding from
infected cells