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  • Mesoderm Endoderm Ectoderm Germ Cells: Pluripotency

    Загружено:

    Dharmendra Maurya
    22 просмотров1 страница
    This document outlines the biological pathways involved in pluripotency and differentiation. It shows that pluripotency is regulated by genes such as OCT4, SOX2, Nanog, and Lin28. These genes allow stem cells to differentiate into the three germ layers - ectoderm, endoderm, and mesoderm - and subsequently into specific adult cell types like neurons, pancreatic cells, heart muscle, and more. Arrows and labels indicate genes, transcription factors, ligands, and cell functions involved in each differentiation pathway.

    Исходное описание:

    STEM CELL

    Оригинальное название

    Pluri Potency

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    This document outlines the biological pathways involved in pluripotency and differentiation. It shows that pluripotency is regulated by genes such as OCT4, SOX2, Nanog, and Lin28. These genes allow stem cells to differentiate into the three germ layers - ectoderm, endoderm, and mesoderm - and subsequently into specific adult cell types like neurons, pancreatic cells, heart muscle, and more. Arrows and labels indicate genes, transcription factors, ligands, and cell functions involved in each differentiation pathway.

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    © All Rights Reserved
    Скачайте в формате PDF, TXT или читайте онлайн в Scribd
    Отметить как неприемлемый контент
    22 просмотров1 страница

    Mesoderm Endoderm Ectoderm Germ Cells: Pluripotency

    Загружено:

    Dharmendra Maurya
    This document outlines the biological pathways involved in pluripotency and differentiation. It shows that pluripotency is regulated by genes such as OCT4, SOX2, Nanog, and Lin28. These genes allow stem cells to differentiate into the three germ layers - ectoderm, endoderm, and mesoderm - and subsequently into specific adult cell types like neurons, pancreatic cells, heart muscle, and more. Arrows and labels indicate genes, transcription factors, ligands, and cell functions involved in each differentiation pathway.

    Авторское право:

    © All Rights Reserved
    Скачайте в формате PDF, TXT или читайте онлайн в Scribd
    Отметить как неприемлемый контент
    из 1

    ePath

    SOX2

    Nanog

    OCT 4

    Lin28

    BIOLOGICA L PAT H WAY M A P S

    Pluripotency

    DAZL

    DDX4

    Teratome

    PLAP

    Female
    germ cells

    Ectoderm

    EN1

    IFITM3

    Male
    germ cells

    Cripto 1

    Neural

    Islet-1

    Endoderm

    GFAP

    Gata4

    FOXA2

    PDX1

    Mesoderm

    AFP

    LEF1

    Lung

    Pancreas

    P -P
    Transcription
    Factor

    Ligand

    Other

    Receptor

    Phospho
    Activation/
    Deactivation

    Heart

    Vessel

    BMP4

    Intestine

    Bone

    Phosphatase

    CD34

    Skin
    Liver

    Kinase

    CD31

    Membrane

    Cell Function

    Activation

    Inhibition

    Indirect Effect

    Dissociation

    Binding/
    Association

    Blood

    Epitomics.Inc.
    All rights
    reser
    ved ved
    2012 Epitomics
    All rights
    reser
    Ver. ID: 46.1.1111
    48.1.1111

    www.epitomics.com /pathways

    Pluripotency Pathway

    Germ Cells

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