Scribd Logo
Загрузить

Добро пожаловать в Scribd!

  • Arrdc3 β4: M GFP Arrdc3 M GFP β4

    Загружено:

    thalianguyen
    12 просмотров1 страница
    ARRDC3 promotes the degradation of p27, a cell cycle inhibitor, by interacting with β-arrestin and targeting p27 for ubiquitination and proteasomal degradation. ARRDC3 recruits the deubiquitinating enzyme SIRT2, which removes ubiquitin from ARRDC3, allowing it to continuously transport p27 to the proteasome for degradation and promote cell cycle progression. Overexpression of ARRDC3 promotes cell proliferation by degrading p27.

    Исходное описание:

    new results

    Оригинальное название

    11.20.14

    Авторское право

    © © All Rights Reserved

    Доступные форматы

    PPTX, PDF, TXT или читайте онлайн в Scribd

    Этот документ был вам полезен?

    Это неприемлемый материал?

    Пожаловаться на этот документ
    ARRDC3 promotes the degradation of p27, a cell cycle inhibitor, by interacting with β-arrestin and targeting p27 for ubiquitination and proteasomal degradation. ARRDC3 recruits the deubiquitinating enzyme SIRT2, which removes ubiquitin from ARRDC3, allowing it to continuously transport p27 to the proteasome for degradation and promote cell cycle progression. Overexpression of ARRDC3 promotes cell proliferation by degrading p27.

    Авторское право:

    © All Rights Reserved
    Скачайте в формате PPTX, PDF, TXT или читайте онлайн в Scribd
    Отметить как неприемлемый контент
    12 просмотров1 страница

    Arrdc3 β4: M GFP Arrdc3 M GFP β4

    Загружено:

    thalianguyen
    ARRDC3 promotes the degradation of p27, a cell cycle inhibitor, by interacting with β-arrestin and targeting p27 for ubiquitination and proteasomal degradation. ARRDC3 recruits the deubiquitinating enzyme SIRT2, which removes ubiquitin from ARRDC3, allowing it to continuously transport p27 to the proteasome for degradation and promote cell cycle progression. Overexpression of ARRDC3 promotes cell proliferation by degrading p27.

    Авторское право:

    © All Rights Reserved
    Скачайте в формате PPTX, PDF, TXT или читайте онлайн в Scribd
    Отметить как неприемлемый контент
    из 1

    M

    GFP

    GFP

    ARRDC3

    GFP

    ARRDC3

    p27

    Actin

    ARRDC3

    Actin

    GFP

    SIRT2-1

    SIRT2-2

    SIRT2
    myc

    myc

    11/20/14

    Вам также может понравиться