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Lactation
4.Eliminasi
Increased renal blood flow (RBF)
Drugs in Pregnancy
The FDA classifies drugs into 5 categories of
safety for use during pregnancy :
1. Category A: safe
Ex : antacids, Bisacodyl, methyl dopa,
paracetamol
2. Category B: unlimited usage
Ex : salmeterol, Gol.Sefalosporin, prazosin
Drugs in Labor
1. Oxytocic
Drugs that increase the strength of uterine
contractions
a. Oxytocin
b. Ergot alkaloids
c. Prostaglandins E and F
2. Tocolytic
Drugs that reduce / inhibit uterine contractions
Purpose: Prevent premature labor, so that the
fetus can be prepared aterm born
Adrenergic 2: Pitodrin, terbutaline
Pitrodine will stimulate 2 receptors on uterine
smooth muscle
L1 (safest)
L2 (safer)
L3 (moderately safe)
L4 (possibly hazardous)
L5 (contraindicated)