I.

PATHOPHYSIOLOGY (CLIENT BASED )

Precipitating Factor:
-trigger effect

Predisposing Factors:
-female
-age: 30-50
-genetic defect
Hx of goiter

Genetic malfunction causing

auto immune response

Recognition of TSI in
extra ocular muscles

Accumulation of fluids and fats

in the extra ocular muscles
Swelling behind the
eyeballs
Exophthalmos

Blurring of vision

Impaired visual
acuity

Drug Therapy
-Furosemide
-spironolactone
Increase production
of T3 hormone

Decrease in TSH

Legend:
Production of thyroid stimulating
immunoglobulins(TSI)

TSI binds in thyrotrpin

receptors(TSH) receptors

Over stimulation of thyroid

gland

Green Disease
Process
Violet Signs and
Symptoms
Blue - Desired
Treatment
Yellow-Management
Red- Disease
Pink- NCP
Orange- Laboratory

Diffuse enlarge ment of the

thyroid gland

Graves Disease

Drug Therapy
Antithyroid
drugs
propylthiouracil
(PTU)

Increase in thyroid function

Hyperthyroidism

November 18, 2014

T3:300 ng/dl
(52-85 ng/dl)
T4:11.4 Ug/dl
(4-11 Ug/dl )

Increase production
of T4 hormone

Increase in BMR

Increase production
of T3 hormone

Decrease in TSH
Drug Therapy
-Adrenergic receptor
blockers
propranolol
atenolol
Cardiovascular System
Increased rate
and force of
cardiac
contractions
Bounding,
rapid
pulse
Increased cardiac
output
November 17, 2014
CHEST X-RAY
IMPRESION:
CARDIOMEGALY

Hyperthyroidism

Increase production
of T4 hormone

Increase in Basal
Metabolic Rate

Over Stimulation of
metabolic rate

Increase the body's sensitivity

to Catecholamine

Integumentary System
Warm,
smooth,
moist
skin
Premature graying
(in men)

Risk for impaired skin

integrity

Activity intolerance

Ineffective tissue
perfusion

Nervous System
Nervousness
Fine tremor (of
fingers
and
tongue)
Restlessness
Exhaustion
Imbalanced nutrition :
less than body
requirements

Gastrointestinal System
Increased
appetite,
thirst
Weight
loss
Increased
peristalsis
Increased bowel
sounds
Hepatomegaly

Liver enzymes November

21, 2014

Fatigue

AST43.7 U/L(0-40)
ALT49.6 U/L(0-41)
Self-care deficit

Musculoskeletal System
Fatigue
Muscle
weakness
Proximal
muscle
wasting

Respiratory System
Increased respiratory
rate
Dyspnea on mild
exertion

Ineffective breathing
pattern
Risk for fall