A Lewis acid is aIso caIIed an eIectrophiIe. When a Lewis base reacts with an eIectrophiIe other than a proton, the Lewis base is aIso caIIed a nucIeophiIe. In this exampIe, BF 3 is the eIectrophiIe and H 2 O is the nucIeophiIe. eIectrophiIe nucIeophiIe Acids and Bases Two other exampIes are shown beIow. Note that in each reaction, the eIectron pair is not removed from the Lewis base. Instead, it is donated to an atom of the Lewis acid and one new covaIent bond is formed. Lewis Acids and Bases Acids and Bases
International ERS - ESICM - ESCMID - ALAT Guidelines For The Management of Hospital-Acquired Pneumonia and Ventilator-Associated Pneumonia - European Respiratory Society