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1-16-15
1st period
Muscle System Lab Report
1
The muscle structure is made up of three types of muscles: cardiac muscle, skeletal muscle, and smooth
muscle.
A skeletal muscle contains many long fibres arranged in bundles called fascicles. Each fibre
consists of smaller strands, called myofibrils. These contain yet smaller parts called myofilaments. A
muscle contracts when sets of these myofilaments slide past each other in response to nerve signals.
The
cardiac muscle
contracts tirelessly throughout life to pump blood from the heart to the lungs and around
the body. It is made up of a network of branching muscle fibres.
skeletal muscle are attached to bones
by tendons, so we are able to move our body parts to move around. the smooth muscle is found in the
walls of the internal organs.
Proteomic and metabolic analysis show abnormal oxidative metabolism in
PAH skeletal muscle. PAH means Polycyclic aromatic hydrocarbon.
EM of PAH patients reveals abnormal mitochondrial structure and distribution. Abnormal
mitochondrial health and function contribute to exercise impairments of PAH. PAH may be
considered a vascular affliction of heart and lungs with major impact on peripheral muscles. (
J
Mol Med (Berl).
2014 Dec 30. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/25548805?report=abstrac
t)
Historically, the term
tendonitis has been used to describe overuse tendon injuries. However, analysis of supposedly
inflamed tendons reveals an absence of inflammatory cells and chemicals, and the term
tendinopathy is now used to describe pathological changes associated with Achilles tendon
injury (13). Within the umbrella of tendinopathy, the majority of runners suffering Achilles pain
will exhibit pathological changes referred to as tendinosis.
(
http://www.pponline.co.uk/encyc/achilles-tendon-muscle-structure-and-injury-rehabilitation-40
869
)
Aurora Vargas
1-16-15
1st period
Muscle System Lab Report
2
figure 1: a skeletal muscle is composed of variety of tissues, including layers of connective tissue.
figure 2: relaxed. and figure 3 fully contracting. when a skeletal muscle contracts, individual
sarcomeres shorten as thick and thin and thin filaments slide past one another.
Aurora Vargas
1-16-15
1st period
Muscle System Lab Report
3
figure 4 and figure 5: transmission electron micrograph showing a sarcomere shortening during muscle
contraction.
Myofiber Length
2-4 length of
myofibers before
ATP solution
length of
myofibers after
ATP solution
Initial contracted
degree of
contraction
% contraction
Trial 1
15mm
10mm
5mm
33%
Trial 2
15mm
12mm
3mm
20%
Trail 3
22mm
15mm
7mm
32%
Trail 4
18mm
11mm
7mm
39%
Trail 5
13mm
8mm
5mm
33%
Aurora Vargas
1-16-15
1st period
Muscle System Lab Report
4
Myofiber Diameter
diameter before
ATP
diameter after
ATP
degree of
diameter change
% diameter
change
trial 1
7mm
14mm
-7
-100%
trial 2
3mm
7mm
-4
-133%
trial 3
4mm
6mm
-2
-.005%
-78%
DATA
Table 1
Continuous Grip
Time interval
10 s
99.4N
20
30 s
119.1N
-19.7N
40
50 s
77.8N
41.3N
60
70 s
55.1N
22.7N
80
90 s
132.8N
-55.1
Table 2
Repetitive Grip
Time interval
10 s
186.7N
20
30 s
148.3N
38.4N
40
50 s
243.2N
-94.9N
60
70 s
274.0N
-30.8N
80
90 s
240.8N
33.2N
Aurora Vargas
1-16-15
1st period
Muscle System Lab Report
5
slow oxidative
fast
oxidative-glycolytic
fast glycolytic
Fiber Diameter
smallest
intermediate
largest
Force
lowest
intermediate
greatest
Myosin ATPase
fastest
faster
slowest
Contraction Velocity
slow
faster
fastest
Methods of ATP
Generation
respiration
glycolysis
glycolysis
Glycogen stores
high
intermediate
low
Capillaries
many
few
few
Myogloblin Content
high
intermediate
low
Color
red brown
red-pink
white