wares oa % q = Pnge ios Canine Health Boat oow) Hyporyroism HEALTH TESTING RESOURCES SIGN UP Stay iformed ofthe latest progress mn eannereath research, ‘Aveady register? LOGIN Fanconi Synarome | AKC Canine Healtn Foundation CONTACTUS FUNDED RESEARCH FORRESEAROWERS NEWS DONATE ‘sean Fanconi Syndrome Fanconi Syndrome: An Overview Fanconi syndiome isa condton where the lubules ofthe kidneys do nat {reten propor. Inthe normal kinoys the tubulos there func to reabsor> ‘taming, minerals, and sugars back info te Boy fo be reused. In Fancans fected dogs the reabsorpion ofthese soktes does not occur and ae Consequerdly dumped ite the wine and excited. The sles affected Include scam, eucose, phosphorus, amine acl, potassium. and Deafbooate. The lst of hese glues can lea Io deyeratin and eectralyle imbalaneo along wth ator problems as wel, The diseate is progressive ‘hough rate of progression is variable, ‘Te most common bred afected by his tease i the Basen. genetic in nature and there is curry a nkage test avaiable to Oveders. The test ‘es rat locate the specie gene for Fancon’s fut sa tool breeders can use {omprove ine breeding program. Cine breeds when havea high prevalence ofthe condition are Norwegian Elkhounds and Schnauzer. Causes of Fanconi Syndrome In some breeds, primarily the Basen, Fancorssyrome is genetic meaning it's passed down from parents fo offspring. There are cases however where ‘ne dsease Is aoqures ue o llopatue (unknown) means or fom medeaton sie affects In mary cates shard oierentate between ‘genetic and idiopathic causes. ‘Symptoms of Fanconi Syndrome ‘Toa most commen signs associated with Fancon syndrome ae ply and palyuta or excessive aking ana winsting respective. Th 8 do ‘he irably ofthe dogs to concertrate ther rine. Weight oss and overall oor contin ae also seen in Fanconi affected dogs. Ae the condton progresses electryte imbalances and metabo aeiosis may occu ls. Diagnosing Fanconi Syndromo Feanceni syndrome is dagnosed by testing the levels of sols inthe urine andthe bod, Dogs with Fancon syne wl have gh amounts of the oles normaly reabsorbed back int the body inclsing glucose, som Phospnons, amino acids, potassium, and bicarbonate, Ary comin of ‘hese can be present One ofthe more common signs of Fancans is igh levels of glucose inte urine wth normal levels of glucose in he blood, Along th une fests, blog tests ae also performed Io determine tne level of the Soles inthe boo Troating Fanconi Syndrome ‘Tare curenty no treatment which can the tubular defect which causes Fanconi?s. The tealment suggested isto cortal the ease allowing the ‘9 ole along, Pappy Ie, Fresh watrshodd alvaye be avaiale, Ts reduces the chance ofthe dog becoming dehyeratea. Research done by Steve Gonio has lead (0a polocal wich spenes wal supplements can be ‘vena help regulate the dog solute eves, The Gono protocol, or Fancor prstocal, canbe found st Fits ww bsser. ra Clsbdocs!tanconprotecai2003 pt or ‘wn zaraebasenjs comipotocl Him, Thete ste give an in depth ook a ‘he protocol an how f canbe agmiistere. The most important objective in ‘vestments to preven melabole sedoss which canbe fla. Each dog ‘thule evalated on a ividal bakes a8 ro one case isthe same Care for Dogs with Fanconi Syndrome ‘Once Fancon! Syndrome Is under eortl the dog an be teated ke ary ‘lhe’ dog ae willbe able to participate in normal famly actives such 95 Fiking runing. Supplmarts shouldbe gvan routinely as rected by your ‘Veteran and anual tests hous be done to cont ta the Fanconi Sti une cont Its suggestes that in dogs which area a great ok ta develop Fancon's manly a8 Basen, be tested for glucose nthelrurne once a marth staring fl age 3. This canbe done using lest eis which ae avalale at most pharmacies. negative fect doesnot mean tat your dog does not Nave hipudranakect rotaninehealiyour-cogs-ealhiseas:nfrmonfancan-syniromeltinl HELP FUTURE GENERATIONS OF DOGS needed Ror hea dogs and dogs Stace by speci eseases [BROWSE OUR RESEARCH ‘Search ou resestch portato see whalroscarch we we funding en Darian disease, MAKE A TRIBUTE, onaton we wllposta pot of your (dog our Calbraon Wal galley TELL US YOUR STORY researen? whatmabuntes youn he fgntaganstcanine dsease? We 42wares Fanconi Synarome | AKC Canine Healtn Foundation Fanconi. High risk dogs shout cortinue tobe tested every month as the synarome can develop at any pot. Just as a negative fest doesnot moan ‘he dog doesnot have the condition, posve urine glucose test does not indeate tat to dg has Fanconi, but san incaton that further esting Should oe dana. Eay detection ofthe disease decreases the isk of kdnoy ‘Semage. With proper management these dogs can veto oges sim to hose witout Faneon syrtome, ‘The AKC Canine Health Foundation and Fanconi Syndrome ‘The AKG Canine Healy Foundtin has funded 4 projects from the Unversity of Missouri on researching Fancon! syrome inthe Basen. The funds, ‘ah oa $52 000, nave been used to develop a gens inkage test ta help Basen breeders. Reseach corms wt the hope that eventually the Specie gone associat wth the contin wl bo defi RELATED GRANTS + Q0801-A Charctriaton oft Mulan Response for Fanon Sinden i Bsssnia yconvio hipudranakect rotaninehealiyour-cogs-ealhiseas:nfrmonfancan-syniromeltinl 22