Pathophysiology

Precipitating Factors:Predisposing Factor:

High Fat, Low Vegetable Diet
Age
Occupation: Field Worker

DNA damage to semensecreting glands of Prostate

Expression of altered gene

products and loss of
regulation

Malignant Neoplasm of the

Prostate

PSA levels

Slo
wly
gro
ws
ove
r
time

Stage I
Stage II

Asymptomatic

Stage III

Stage IV (Tumor grows big

enough)

Metastasize to Spine

Spinal Cord
Compression
Constriction of Urethra

Low Back
Pain
Weakness and
Hypoesthesia of
Lower Extremities

Dysuria, Weak urine stream,

Urinary Retention

Constipation