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AP: CHAPTER 16: THE MOLECUSI~I~~’IIIIIIIIIID

1. After Morgan and fellow scientists developed the Chromosomal Theory of Inheritance, the
search was on for the chemical mechanism of inheritance. What are the two components of
the chromosome?

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2. From initial logic, which componenuwould be the most likely candidate for the genetic
material and why?

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3. What did Griffith, Avery, and others accomplish with bacteria?

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5. What did the experiments done by Alfred Hershey and Martha Chase show?

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6, What are Chargaff’s rules?

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7. If a species has 35% adenine in its DNA. determine the percent of the other three bases.

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8. What was the role of Maurice Wilkins and Rosalind Franklin in determining the structure of
DNA?

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9. Use the diagram to describe the structure of DNA. Include several comments.
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DNA structure

10. What is the advantage of the double stranded aspect of the DNA? TYU. douJ,L -

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11. Which model of DNA replication is accepted? /u42tJi cn’i 3€ru LI41 ~c

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12. What happens at the DNA replication fork?

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13. Make a list of the enzymes involved in replication and their role.

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14. Why does the DNA have to add nucleotid~i1nthe 5’ to 3’ direction? ~ nn~ 6~ ki—t La St.

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15. Label the diagram of DNA replication. Include the directions and the terms.

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16. Describe the “priming of the DNA” before replication. 2~-Wrcac &*-t sbtrf— st~-ck-cW~~

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17. List some of the steps involved in DNA repair. h/U 4\ nnno-St& yrvo-trea d

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18. What is the problem that occurs at the ends of the chromosome during replication?

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19. What is a telomere and its role in cell division. A I-dblnt¾-e ~c, a t~A St~ict

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20. Why was there no se~~ion

pressure for prokaryotes to evolve a telomere-Iike solution on

theirchromosome? ‘~~wV.&4ty-~I’eshiw€ (tc (L&ic.C rt~U,A 0~

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21. Why is telomerase an active area in cancer research? TktrnuA-OSC LC-t1’Ah3 ~1&1

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