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  • Pathophysiology Dengue Hemorrhagic Fever

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    shiramu
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    Pathophysiology: Age, Heredity, Sex, Age Precipitating Factors: Aedes Aegypti Mosquito bite virus enters into the host's blood stream platelet will provide a shield for the virus from exposure and binding to neutralize pre-existing antibody Infects cells and replicates in sufficient amount Initiates an immune response activation of memory T-cell response during re-exposure Stimulates release of cytokines High fever

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    Pathophysiology Dengue hemorrhagic fever

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    Pathophysiology: Age, Heredity, Sex, Age Precipitating Factors: Aedes Aegypti Mosquito bite virus enters into the host's blood stream platelet will provide a shield for the virus from exposure and binding to neutralize pre-existing antibody Infects cells and replicates in sufficient amount Initiates an immune response activation of memory T-cell response during re-exposure Stimulates release of cytokines High fever

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    Attribution Non-Commercial (BY-NC)
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    12K просмотров1 страница

    Pathophysiology Dengue Hemorrhagic Fever

    Загружено:

    shiramu
    Pathophysiology: Age, Heredity, Sex, Age Precipitating Factors: Aedes Aegypti Mosquito bite virus enters into the host's blood stream platelet will provide a shield for the virus from exposure and binding to neutralize pre-existing antibody Infects cells and replicates in sufficient amount Initiates an immune response activation of memory T-cell response during re-exposure Stimulates release of cytokines High fever

    Авторское право:

    Attribution Non-Commercial (BY-NC)
    Скачайте в формате DOC, PDF, TXT или читайте онлайн в Scribd
    Отметить как неприемлемый контент
    из 1

    Pathophysiology

    Predisposing
    Precipitating Bite of a virus carrying Factors:
    Factors: mosquito Age, Heredity, Sex,
    Aedes Aegypti Age
    Mosquito
    Mosquito injects fluid into
    patient’s skin

    Virus enters into the host’s blood


    Platelet will provide a stream
    shield for the virus from
    exposure and binding to Infects cells and replicate in sufficient
    neutralize pre-existing
    amount
    antibody
    Initiates an immune
    response

    Activation of memory T-cell Stimulates


    Macrophages or monocytes response during re-exposure ---
    release of
    engulfed the virus having
    cytokines
    the platelet (phagocytosis)
    Virus- anti body complex High fever, body
    (Binding of ab-virus) weakness,
    headache and
    dizziness
    AB- enhance uptake

    Cytokines destroy cell


    membrane and cell wall
    Cytolysis
    (viral antigens found in
    monocytes)

    Complement system
    activation
    Coagulopa Thrombocytope Vasculopathy
    thy nia (plasma Vascular endothelial
    (PT/APTT) (< 100x109/L) leakage) activation

    Fluid shifting ICF to Management:


    ECF Promote bedrest
    Medication
    Rapid replacement of body
    fluids
    Blood transfusion
    Precautions

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