Академический Документы
Профессиональный Документы
Культура Документы
rectal cancer
Pathophysiology of Moderately Differentiated
Heredity Polyps
Adenocarcinoma, Ano- Rectal Mass, Stage IV
Inflammatory Bowel Disease Diet (high fat, low
fiber)
Negatively affects the DNA repair Cells grow and divide very quickly Allows unchecked cellular replication
at the crypt surface
Inability to control proliferation of affected cells Increases survival and proliferation of cancer cells causes further mutations
P53 mutations
Prevent apoptosis
Regenerates
Activated oncogenes
Mutation and inactivation of p53 gene crypt cells migrate from the base
To the surface
Anus
ANO-RECTAL MASS biopsy was done revealing well –
differentiated adenocarcinoma of the
ano-rectalmass
Endoscopy reveals circumferential Affects the rectum rectal exam was done
Ulcerating,friable mass measuring 9cm
Length starting from the anal verge
Affects adjacent structures enters the lymphatic vessels spreads to regional and
local lymph nodes
Endoscopy was done showing extension vaginal bleeding chest x-ray was done with impression
of calcified
Of tumor in the post vaginal wall Extends to the vaginal wall pulmonary nodule in the
right lower lobe
Speculum exam was done revealing 1 cm Foul smelling discharges
Ulceration on post vaginal wall
Changes in diet tumor tends to bleed or bowel obstruction invades or compresses nerve trunks
Due to ulcerating mass
Body weakness Loss of blood CBC, typing, platelet count was done
Loose bowel movement
Pallor
Legend:
- Manifestations/signs and
symptoms
- Procedures/ Diagnostic Tests
- Management / interventions
- Predisposing factors / causes
- Affectations of Ano – Rectal
Mass