UNIT 1.

3: BLOOD CLOTTING MECHANISM

1. Thrombin, fibrin, prothrombin and fibrinogen are four types of protein.
Thrombin, fibrin, prothrombin dan fibrinogen adalah empat jenis protein.
Which of the following sequences is true for the involvement of these
proteins during blood clotting?
Antara urutan berikut, yang manakah betul dalam penglibatan proteinprotein itu semasa pembekuan darah?
A
B
C
D

Thrombin, fibrin, prothrombin, fibrinogen

Fibrin, prothrombin, fibrinogen, thrombin
Prothrombin, thrombin, fibrinogen, fibrin
Fibrinogen, fibrin, prothrombin, thrombin

2. Which of the following substances causes fibrinogen to change to fibrin?

Antara bahan berikut, yang manakah menyebabkan fibrinogen bertukar
kepada fibrin?
A
B
C
D

Vitamin K
Thrombin
Calcium ion
Thrombokinase

3. A gardener experiences non-stop bleeding after hurting his foot while

gardening. What will happen if his blood is unable to clot?
Seorang pekebun mengalami pendarahan tidak berhenti setelah kakinya
tercedera semasa berkebun. Apakah akan terjadi jika darahnya tidak
dapat membeku?
A
B
C
D

Blood pressure decrease

Tekanan darah menurun
Blood capillaries enlarge
Kapilari darah membesar
The rate of heart beat increase
Kadar denyutan jantung bertambah
The rate of respiration increase
Kadar respirasi bertambah

4. Rajah 8 menunjukkan mekanisme pembekuan darah manusia.

The schematic diagram in Figure 8 shows the mechanism of blood clotting
in humans.

PREPARED BY: NIK NURUL HASLINDA

Tisu darah
Blood tissue

Platlet
Platelets

Trombokinase
Thrombokinase
Vitamin X

Ion Y

Protrombin
Prothrombin

Trombin
Thrombin

Apakah vitamin X dan ion Y?

What are vitamin
X and ion Y?
Fibrinogen

Vitamin X
D

Fibrin

Ion Y
Besi
iron
Kalsium
Calcium
Natrium
Sodium
Kalsium
Calcium

5. Seseorang yang mengalami masalah dalam mekanisme pembekuan

darahnya dikatakan mengalami
A person who has impaired clotting mechanism is said to suffer from
A
C

Hemofilia
Embolisme

B
D

thrombosis
Angina

6. Rajah menunjukkan carta alir mekanisme pembekuan darah manusia.

Figure shows a flow chart of blood clotting mechanism.
Tisu darah
Blood tissue

Platlet
Platelets
P

Vitamin K

Protrombin
Apakah
P, Q dan R?
What Prothrombin
are P, Q and R?

PREPARED BY: NIK NURUL HASLINDA

Q

Ion kalsium
Calcium ion

Thrombin
Thrombin

A
B
C
D

P
Fibrinogen
Thrombokinase
Erythrocytes
Thrombokinase

Q
Fibrin
Collagen
Thrombokinase
Fibrinogen

R
Collagen
Fibrin
Collagen
Fibrin

7. Rajah menunjukkan mekanisme pembekuan darah manusia.

Diagram shows a blood clotting mechanism.
Gumpalan
platlet
Clumped
+
Sel-sel
tercedera
Damaged
+ cells
Factor
pembekuan
Clotting factor

Apakah P, Q dan R?
What are P, Q and R?
A
B
C
D

P
Tromboplastin
Thromboplastin
Trombin
Thrombin
Tromboplastin
Thromboplastin
Protrombin
Prothrombin

P
Ion
Kalsium

Vitamin
K

Fibrinoge
n

Q
Trombin
Thrombin
Protrombin
Prothrombin
Protrombin
Prothrombin
Tromboplastin
Thromboplastin

Fibrin

R
Protrombin
Prothrombin
Tromboplastin
Thromboplastin
Trombin
Thrombin
Trombin
Thrombin

8. Yang manakah antara bahan berikut, menyebabkan protrombin bertukar

kepada trombin?(TRIAL JOHOR 2011)
Which of the following substances causes prothrombin to change to
thrombin?
A
B
C

Vitamin K
Thrombin
Trombin
Ion kalsium

PREPARED BY: NIK NURUL HASLINDA

Trombokinase
Thrombokinase

9. Manakah berikut terlibat dalam proses pembekuan darah?(TRIAL KEDAH

2011)
Which of the following involved in blood clotting process?
A

Globulin, trombin, dan fibrin

B
C
D

Albumin, globulin dan fibrinogen

Trombin, thrombokinase dan fibrinogen
Albumin, protrombin dan trombokinase

10.Rajah menunjukkan satu peringkat dalam mekanisme pembekuan darah.

(TRIAL PAHANG 2009)
Diagram shows a stage in the blood clotting mechanism.

Antara berikut yang manakah menerangkan peringkat ini?

Which of the following statement explains this stage?
A
B
C
D

Tromboplastin menukarkan protrombin kepada trombin

Thromboplastin converts prothrombin to thrombin
Trombin menukarkan fibrinogen kepada fibrin
Thrombin converts fibrinogen kepada fibrin
Platlet merangsang pembentukan jaringan fibrin
Platelets stimulate the formation of meshwork of fibrin
Platlet membebaskan tromboplastin untuk membentuk jaringan fibrin
Platelets release the thromboplastin to form meshwork of fibrin

PREPARED BY: NIK NURUL HASLINDA