Glomerulonefritis Akut

Dewasa

Non Farmakologi
Restrict your salt intake to prevent or
minimize fluid retention, swelling and
hypertension
Cut back on protein and potassium
consumption to slow the buildup of wastes
in your blood
Maintain a healthy weight
Control your blood sugar level if you have
diabetes
Quit smoking

Farmakologi
1.
2.
3.
4.

Antibiotik
Loop diuretik
Vasodilator
Calsium channel blocker

1. Antibiotik
Pennicilin V
500 mg PO q12hr or 250 mg PO q6hr for
10 days
Inhibits the biosynthesis of cell wall
mucopeptide

Erythromyin
400 mg PO divided q12hr for 10 days
Inhibits bacterial growth, possibly by
blocking dissociation of peptidyl tRNA
from ribosomes,

2. Loop Diuretik
Furosemide
20-80 mg PO once daily; may be
increased by 20-40 mg q6-8hr; not to
exceed 600 mg/day
Inhibits reabsorption of sodium and
chloride ions at proximal and distal renal
tubules and loop of Henle; by interfering
with chloride-binding cotransport
system, causes increases in water,
calcium, magnesium, sodium, and
chloride

3. Vasodilator
Hydralazine
10 mg PO q6hr for 2-4 days
Direct vasodilator; dilates arterioles with
little effect on vein; decreases systemic
resistance, which subsequently
decreases blood pressure.

4. Calcium channel blocker

Nifedipine
30-60 mg PO once daily
inhibits transmembrane influx of
extracellular calcium ions across
myocardial and vascular smooth muscle;
this results in inhibition of cardiac and
vascular smooth muscle contraction,
there by dilating main coronary and
systemic arteries