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  • Bone Marker Tests for Bone Resorption & Formation

    Загружено:

    Aniket Mittal
    10 просмотров1 страница
    This document discusses biochemical markers of bone cell activity that can be measured to assess bone formation and resorption. It lists common abbreviations and names of bone turnover markers, including collagen-based markers like NTX, CTX, PYD, and DPD that indicate bone resorption. It also lists markers of bone formation, such as Bone ALP, PICP, PINP, and Osteocalcin, which are secreted by osteoblasts during bone formation. Many of these markers are measured by commercial diagnostic test kits.

    Исходное описание:

    About osteogenesis

    Оригинальное название

    Bone Turnover Markers

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    This document discusses biochemical markers of bone cell activity that can be measured to assess bone formation and resorption. It lists common abbreviations and names of bone turnover markers, including collagen-based markers like NTX, CTX, PYD, and DPD that indicate bone resorption. It also lists markers of bone formation, such as Bone ALP, PICP, PINP, and Osteocalcin, which are secreted by osteoblasts during bone formation. Many of these markers are measured by commercial diagnostic test kits.

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    © All Rights Reserved
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    10 просмотров1 страница

    Bone Marker Tests for Bone Resorption & Formation

    Загружено:

    Aniket Mittal
    This document discusses biochemical markers of bone cell activity that can be measured to assess bone formation and resorption. It lists common abbreviations and names of bone turnover markers, including collagen-based markers like NTX, CTX, PYD, and DPD that indicate bone resorption. It also lists markers of bone formation, such as Bone ALP, PICP, PINP, and Osteocalcin, which are secreted by osteoblasts during bone formation. Many of these markers are measured by commercial diagnostic test kits.

    Авторское право:

    © All Rights Reserved
    Скачайте в формате PDF, TXT или читайте онлайн в Scribd
    Отметить как неприемлемый контент
    из 1

    Biochemical markers of bone cell activity

    BIOCHEMICAL MARKERS OF BONE RESORPTION


    Abbr

    Name

    Mechanism

    Company

    NTX

    Aminoterminal cross-linking telopeptide of


    bone collagen

    Collagen-based

    Ostex (Osteomark)

    CTX

    Carboxyterminal cross-linking telopeptide of


    bone collagen

    Collagen-based

    Cross-laps
    (Osteometer)

    PYD

    Pyridinoline

    Collagen-based

    DPD

    Free Lysyl-pyridinoline (deoxypyridinoline)

    Collagen-based

    TRACP

    Tartrate-resistant acid phosphatase

    Secreted by
    osteoclasts

    Hyp

    Hydroxy-proline (not very specific)

    Collagen-based

    Metra (PyrilinksD)

    BIOCHEMICAL MARKERS
    OF BONE FORMATION

    Abbr

    Name

    Mechanism

    Company

    Bone ALP, BAP

    Bone-specific alkaline
    phosphatase

    Secreted by
    osteoblasts

    Hybritech (Ostase),
    Metra (Alkphase-B)

    PICP

    Procollagen type I C
    propeptide

    Collagen-based Orion, Metra (Prolagen)

    PINP

    Procollagen type I N
    propeptide

    Collagen-based

    Incstar

    OC

    Osteocalcin (bone glaprotein)

    Secreted by
    osteoblasts

    Nichols, Cis
    Biointernational

    ALP

    Alkaline phosphatase
    (not very specific)

    Secreted by
    osteoblasts

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