PATHOPHYSIOLOGY OF PEDIATRIC COMMUNITY-ACQUIRED PNEUMONIA ( c )

Etiology:

Predisposing factor:

Virus ( Streptococcus Pneumoniae,

* Age (11 months)

S. Aureus)

Precipitating factor:
*Environment
Affected Part:
LUNGS

Aspiration of secretion containing microbes

Failure of defense mechanisms
Invasion of lower respiratory tract
Activation of B cells
Release of antibodies
Antigen-antibody reaction

Antigen antibody complexes adhere to the

mucosal lining

Infection lodges stimulates in the

parenchyma

Lung invasion

Narrowing air passage (pallor, tachypnea)

Leukocytes increased (fever)

Mucosal irritation (cough)

Ineffective airway clearance