Name________Jawan Browder_______

Date___4/12/16____

Genomes, Chromosomes, and DNA Web Quest

Topic: Genomes and Chromosomes
Go to: http://ghr.nlm.nih.gov/handbook/hgp/genome
1. What is a genome?
A genome is an organisms complete set of DNA, including all of its genes.

2. On the left hand side, click on cells and DNA. Explore this site to answer the
following questions:
a. What is a chromosome?
A chromosome is a DNA molecule that is packaged into thread-like
structures

b. When are chromosomes visible?

A chromosome is visible under a microscope when it becomes more
tightly packed during cell division

c. What is a centromere?
A constriction point in a chromosome, which divides the chromosome into
two sections, or arms.

d. How many chromosomes do people have?

23 pairs of chromosomes, which total 46

Go to: http://learn.genetics.utah.edu/content/begin/traits/karyotype/
3. What is a karyotype?
A karyotype is an organized profile of a person's chromosomes

Modeling Instruction AMTA 2012

Unit 6 Growth and Reproduction

Name________Jawan Browder_______

Date___4/12/16____

4. Match the chromosomes to complete the karyotype (turn on hints for help). Is the
karyotype from a male or female? How do you know?
For a male, X and Y chromosomes
5. Predict what would happen if a person has the incorrect number of
chromosomes. Write your prediction here.
Disease or die

6. Do a quick google search to find the answer to question 5.

If its incorrect, one cell may get two copies of a chromosome, while another cell
gets none. Incorrect distribution of chromosomes is called nondisjunction

As a class you determined that chromosomes must be duplicated before the cell can
divide. This process is called DNA Replication.
Topic: DNA Replication
Go to: http://www.pbs.org/wgbh/aso/tryit/dna/shockwave.html
Click: DNA replication (upper left) and then click unzip Read the script, answer the
questions below, and then, click OK.
1.

In a real cell, what does the DNA molecule do before it unzips?

2.

What molecules break the rungs (bases) apart?

Drag the correct bases over to synthesize the new DNA halves.
Read script, answer questions, and then click OK.
3.

How many base pairs are in the real human genome?

Modeling Instruction AMTA 2012

Unit 6 Growth and Reproduction

Name________Jawan Browder_______

Date___4/12/16____

Go to: http://nobelprize.org/educational_games/medicine/dna_double_helix/
Click on Play DNA Game; Click next and reading each page, continue to click next
until you come to the game.; Click on organism #1 and match the base pairs as fast as
you can! It is hard.
Click next and then click on each organism until you identify the one that belongs to
chromosome #1; continue playing the game with the other two chromosomes, filling in
the chart below.
Be careful, other teams may get different results.
Chromosome #
1

How many
chromosomes?
5

How many
base pairs?
125

How many
genes?
25000

What is the
organism?
Thale cress

14

22.7

5300

Malaria
parasite

16

11.7

6300

Bakers yeast

Topic: Mutations
Go to: http://evolution.berkeley.edu/evolibrary/article/mutations_03
Read the information and fill out the table below:
Type of mutation
Substitution

Description
is a mutation that exchanges one
base for another

Insertion

mutations in which extra base pairs

are inserted into a new place in the
DNA.
Mutations in which a section of DNA

Deletion

Modeling Instruction AMTA 2012

Effect on resulting protein

change a codon to one that encodes a
different amino acid and cause a small
change in the protein produced

Unit 6 Growth and Reproduction

Name________Jawan Browder_______

Date___4/12/16____

is lost, or deleted.
Frameshift

A change that alters a gene so that its

message is no longer correctly
parsed

Modeling Instruction AMTA 2012

Unit 6 Growth and Reproduction