Академический Документы
Профессиональный Документы
Культура Документы
Questions
1.Amyloidplaquesandneurofibrillarytanglesarethehallmarksof:
a.Alzheimer'sdisease
b.Amyotrophiclateralsclerosis
c.AtaxiaTelengiectasia
d.Autism
2.Difficultyspeakingandunderstandingspeechistermed:
a.Apnea
b.Ataxia
c.Aphasia
d.Dyslexia
3.Themostcommonformoftransientfacialparalysisis:
a.Alzheimer'sdisease
b.Transientischemicattack
c.Bell'spalsy
d.Erb'spalsy
4.Graduallyincreasingpainandweaknessandnumbnessinthehandorwristthat
radiatesupthearmsuggest:
a.Amyotrophiclateralsclerosis
b.Carpaltunnelsyndrome
c.BlochSulzbergerSyndrome
d.Dystonia
5.AllofthefollowingmaybeassociatedwithGuillainBarreSyndromeexcept:
a.Weakeningortinglingsensationinthelegs
b.Weaknessinthearmsandupperbody
c.Nearlycompleteparalysis
d.Firstsymptomisalteredmentalstatus
6.Whichofthefollowingstatementaboutherpeszosterisnottrue?
a.Itiscausedbythevaricellazostervirus
b.Itcausesburning,tinglingpainandlesions,generallyononesideofthebody
c.Anyonewhohashadchickenpoxisatriskofpostherpeticneuralgia
d.Itisasexuallytransmitteddisease
7.Diagnostictestsforepilepsyincludeallofthefollowingexcept:
a.Simplebloodtests
b.EEG
c.Brainscan
d.Wadatest
8.Treatmentforepilepsytoeliminateorsharplyreducethefrequencyofseizuresmay
involveallofthefollowingexcept:
a.Cognitivebehavioraltherapy
b.Narrowspectrumandbroadspectrumantiepilepticdrugs
c.Vagusnervestimulation
d.Surgery
9.Themostcommoninheritedneurologicaldisorderis:
a.BlochSulzbergerSyndrome
b.CharcotMarieToothdisease
c.Alper'sdisease
d.AspergerSyndrome
10.Asevereformofepilepsythatappearsduringthefirstyearoflifeiscalled:
a.DandyWalkersyndrome
b.Devic'ssyndrome
c.Dravetsyndrome
d.Fabrydisease
11.Lackofceramidetrihexosidase,alsoknownasalphagalactosideAcauses:
a.Fahr'ssyndrome
bFabrydisease
c.Fishersyndrome
d.Gaucher'sdisease
12.Symptomsoftrigeminalneuralgiamayincludeallofthefollowingexcept:
a.Extreme,intermittentfacialpaininthejaworcheek
b.Tinglingornumbnessononesideoftheface
c.Paintriggeredbycontactwiththefaceorfacialmovements
d.Inabilitytoswallow
13.AllofthefollowingaretrueaboutTourettesyndromeexcept:
a.Drugtreatmentcompletelyeliminatessymptoms
b.Itisinvoluntaryandmaybeachroniccondition
c.Symptomsaregenerallymostsevereduringadolescence
d.Symptomsaregenerallydetectedinchildren
14.Huntington'sdiseaseisaheritabledisorderthatinvolves:
a.Suddenparalysis
b.Chorea,lossofcognitiveabilities,andemotionaldisturbance
c.Uncontrollableswearingandrepetitiveactions
d.Inabilitytorecognizefaces
15.Allofthefollowingstatementsaboutamyotrophiclateralsclerosisaretrueexcept:
a.Itcausesdegenerationanddeathofupperandlowermotorneurons
b.Patientslosestrengthandcontrolofvoluntarymuscles
c.Itimpairscognitionandsenses
d.Itprogressesrapidlyandisfatal
16.ChildrenwithAngelmansyndromegenerallydisplayallofthefollowingexcept:
a.Developmentaldelaysandspeechimpairment
b.Feedingproblems
c.Seizures
d.Lossofhearingandsenseofsmell
17.Allofthefollowingaretrueaboutautismexcept:
a.Affectedpersonshavecommunication,interpersonal,andbehavioralproblems
b.Affectedpersonsdisplayobsessiveorrepetitivebehaviorsandinterests
c.Itisthedirectresultofimmunizationwiththimerosalcontainingvaccines
d.Earlyinterventionisassociatedwithimprovedoutcomes
18.Brainandspinaltumorsmaybetreatedwithanyorallofthefollowingmodalities
except:
a.Surgery
b.Radiation
c.Chemotherapy
d.Positronemissiontomography
19.SymptomsofParkinson'sdiseaseincludeallofthefollowingexcept:
a.Tremorsofthehands,arms,legs,jaw,andface
b.Stifflimbs
c.Bradykinesiaandimpairedbalance
d.Impairedcognition
20.Narcolepsyisadisordercharacterizedby:
a.Narcoticabuse
b.Grandmalseizures
c.Relianceonsoporificdrugs
d.Inabilitytoregulatesleepwakecycles
AnswersandExplanations
1.A:Alzheimer'sdisease(AD)isaspecifictypeofdementiaandthemostcommonformof
dementiainpersonsage65andolder.Itisaprogressiveneurologicaldiseasethatproducesa
declineincognitivefunctionandmemoryandchangesinbehavior.Inadditiontotheabove
mentionedfeaturesofAD,thereisalossofconnectionsbetweentheneuronsinvolvedwith
learningandmemory.
2.C:Aphasiaresultsfromdamagetotheportionofthebraininvolvedincreatingand
interpretinglanguage.Aphasiaisnotadisease.Itisasymptomofaneurologicaldisorderor
injury,suchasstroke,braintumor,orheadinjury.Expressiveaphasiaisthetermforproblems
communicatingusingspokenorwrittenlanguage.Receptiveaphasiareferstoproblems
understandinglanguage.
3.C:Bell'spalsyisatemporaryparalysisthatgenerallyaffectsonesideoftheface.Itresults
fromdamageortraumatofacialnerves.Bell'spalsyhassuddenonsetwithsymptomsthatmay
includevaryingdegreesofweaknessorparalysis,droopingeyelidorcornerofthemouth,
drooling,dryeyeormouth,impairedsenseoftaste,excessivetearing,andfacialdistortion.
4.B:Carpaltunnelsyndromeiscausedbycompressionofthemediannerveinthewrist.Asthe
disorderprogresses,thereisalossofgripstrengthandmanualdexteritymaydecrease.Resting
theaffectedwrist,immobilization,icepacks,andnonsteroidalantiinflammatoryagentsmay
providereliefbyreducingswellingandpressureonthemediannerve.
5.D:GuillainBarreSyndromeisarareautoimmunediseasethatoftenfollowsarespiratoryor
gastrointestinalviralillness.Italsomayoccurfollowingsurgeryorimmunization.Thereisno
cureforGuillainBarreSyndrome;however,treatment,includingplasmapheresisandhighdose
immunoglobulintherapyadministeredintravenously,aimstoreducetheseverityofsymptoms.
6.D:Herpeszoster,commonlyknownasshingles,occursalongadermatomeandproduces
characteristicitching,burning,blisters,andpain.Itiscausedbyareactivationofthevaricella
zostervirusthatcauseschickenpox.Theseverityanddurationofanoutbreakcanbereducedby
prompttreatmentwithantiviralagents.Olderadultswhohavehadchickenpoxmaybegivena
varicellazostervirusvaccinetosignificantlyreducetheriskofdevelopingshingles.
7.A:Thediagnosisofepilepsymaybeestablishedusingtheabovementionedtestsaswellas
continuousvideoEEGmonitoring,magneticresonanceimaging(MRI)andfunctionalMRI,and
singlephotonemissioncomputedtomography(SPECT),whichtracescerebralbloodflowto
detectabnormalitiesduringandbetweenseizures.
8.A:Becausepeoplewithepilepsy,especiallychildrenandadolescents,maydevelopbehavioral
oremotionaldifficultiesinresponsetostigmatization,cognitivebehavioraltherapymaybe
consideredasadjunctivetherapy.Itisnot,however,atreatmentfortheseizuredisorder,which
forthemajorityofaffectedpersonsiscontrollablewiththeuseofantiepilepticdrugs.
9.B:CharcotMarieToothdiseaseaffectsanestimated1in2,500personsintheUnitedStates.It
isahereditarymotorandsensoryneuropathythataffectstheperipheralnerves.Assuch,
symptomsincludeweaknessofthefeetandlegsandfootdeformitiesresultingfromweak
muscles,whichinturnmayproducefootdrop,tripping,andfalls.
10.C:Dravetsyndrome,alsoknownasseveremyoclonicepilepsyofinfancy,presentswith
frequentfeverrelatedseizuresduringthefirstyearoflife.Othertypesofseizuresgenerally
occurovertime,andchildrenwithDravetsyndromeareoftendevelopmentallydelayedin
language,motor,andinterpersonalskills.
11.B:PersonswithFabrydiseasecannotefficientlymetabolizelipidsandasaresult,excessive
lipiddepositionoccursintheeyes,kidneys,cardiovascularsystem,andautonomicnervous
system.Symptomsofthisheritablediseaseincludeburningsensationsinthehands,raisedskin
lesions,andinboysespecially,cornealchanges.PersonswithFabrydiseaseareatincreasedrisk
ofheartdiseaseandstroke.
12.D:Trigeminalneuralgiaischaracterizedbysuddenonsetofseverepainthatlastslessthana
minute.Itpresentsmostcommonlyinpersonsage50andolderandamongwomen.The
frequencyandseverityofattacksrecursandremits,progressivelyworseningovertime.While
thedisordermaybedebilitating,itisnotlifethreatening.
13.A:TouretteSyndromeischaracterizedbyticsrepetitive,involuntarybehaviors,
vocalizationsandmovementssuchaseyeblinking,grimacing,andshruggingorjerkymuscle
movements.Ticsalsomayincludeselfharmsuchasrepetitivelypunchingoneselfaswellas
coprolaliaandecholalia.PersonswithTourettesyndromefrequentlysufferbehavioralproblems
suchashyperactivity,impulsivity,attentiondisorders,andrepetitivebehaviors.
14.B:Huntington'sdiseaseisaprogressivebraindisorderthatcausesthedegenerationofcellsin
apairofnerveclustersdeepinthebrain.Thediseaseaffectsboththebodyandthemind.HDis
causedbyasingledominantgeneandaffectsmenandwomenofallracesandethnicgroups.It
generallybeginsduringthethirdandfourthdecadesoflife;however,thereisaformofthe
diseasethatcanaffectchildrenandadolescents.
15.C:Amyotrophiclateralsclerosis(ALS),alsoknownasLouGehrig'sdisease,causesmuscle
weaknessandatrophy.AsitprogressesALSpatientshavedifficultymoving,swallowing,
speaking,andultimately,breathingontheirown.ManyALSpatientsrequiremechanical
ventilationandmostdiefromrespiratoryfailurethreetofiveyearsfromthetimeinitial
symptomsaredetected.
16.D:Angelmansyndromeisageneticdisorderthatcausesdevelopmentaldelaysandmultiple
neurologicalproblemssuchasmotordifficultiesthatimpairfunctions.ChildrenwithAngelman
syndromeareoftenhyperactiveandsufferfrommovement,balance,andsleepdisorders.They
havecharacteristicsmall,flatheadsandprotrudingtongues.Jerkymovementsarealso
characteristicofthedisorder.
17.C:Althoughtheetiologyofautismremainsunknown,itisthoughttoarisefroma
combinationofgeneticpredispositionandenvironmentaltriggers.Areviewoftheevidence
conductedbytheInstituteofMedicineconcludedthatthereisnocausalrelationshipbetween
thimerosalcontainingvaccinesandautism.
18.D:Brainandspinaltumorsmaybebenignormalignantandbenigntumorsmaybe
asymptomaticdependingontheirlocation.Symptomsofbraintumorsincludethefollowing:
headache;seizures;nauseaandvomiting;vision,hearing,andmotorproblems;andsensoryand
cognitivechanges.Symptomsofspinalcordtumorsincludepain,sensorychanges,andmotor
problems.
19.D:SymptomsofParkinson'sdiseaseoftenbeginononesideofthebodyandovertimeaffect
theentirebody.ThefourcharacteristicsymptomsofParkinson'sdiseasearetremor,rigidity,
slownessofmovement,andposturalinstability.Tremorisgenerallymostapparentatrestor
whenthepatientisstressedandimproveswithdeliberatemovement.
20.D:Narcolepsyisaneurologicaldisorderthatcausesaffectedindividualstoexperience
irresistibleboutsofsleep,causingthemtofallasleepforperiodsrangingfromsecondsto
minutesthroughouttheday.Alongwithexcessivedaytimesleepiness,personswithnarcolepsy
alsosufferfromcataplexy,hallucinationsattheonsetofsleepand/oruponawakening,and
transientcompleteparalysisattheonsetorendofsleep.
1.
2.
3.
5.
6.
Which of the following could be seen with the chronic use of phenytoin
(Dilantin)?
(A) Leukocytosis
(B) Increased liver function levels
(C) Hyponatremia
(D) Hypovitaminosis D
(E) Hypercalcemia