CALIFORNIA DEPARTMENT OF PUBLIC HEALTH

OCCUPATIONAL HEALTH BRANCH

CALIFORNIA SAFE COSMETICS PROGRAM
September 1, 2009

CHEMICALS KNOWN OR SUSPECTED TO CAUSE

CANCER OR REPRODUCTIVE TOXICITY
The California Safe Cosmetics Act of 2005 requires cosmetic manufacturers to disclose to the California Department of Public Health (CDPH) all products containing chemicals known
or suspected to cause cancer, birth defects, or other reproductive toxicity. To assist companies with reporting, CDPH compiled this list of chemicals in consultation with the Office of
Environmental Health Hazard Assessment. CDPH used lists and reports available from the authoritative scientific bodies cited in California Health and Safety Code Section 111791.5
(see the last page of this list for details). It should be noted that not all listed chemicals will be found in cosmetic products.

The “INCI Name” (International Nomenclature of Cosmetic Ingredients) is provided for those chemicals that are listed in the International Cosmetic Ingredient Dictionary (11th ed.).
The CAS number is the Chemical Abstract Service (CAS) Registry Number. Not all listed chemicals will include CAS numbers or INCI names. The “Basis for ID” (basis for
identification) cites the authoritative body that listed the chemical. In cases where the chemical was listed under Proposition 65 as well as by other authoritative bodies, only
Proposition 65 was noted.

Note to consumers: Some cosmetic products may not contain any of these chemicals. Also note, the likelihood of a cosmetic product leading to cancer or reproductive harm depends
on many factors, including but not limited to the amount and type of exposure to chemicals in the product. The chemicals are listed here because of findings from research on the
chemicals and not on cosmetic products.

Chemical INCI Name CAS # Type of Toxicity Basis for ID

1 A-alpha-C (2-Amino-9H-pyrido[2,3-b]indole) 26148-68-5 cancer Proposition 65
2 Acetaldehyde Acetaldehyde 75-07-0 cancer Proposition 65
3 Acetamide 60-35-5 cancer Proposition 65
4 Acetazolamide 59-66-5 developmental Proposition 65
5 Acetochlor 34256-82-1 cancer Proposition 65
6 Acetohydroxamic acid 546-88-3 developmental Proposition 65
7 2-Acetylaminofluorene 53-96-3 cancer Proposition 65
8 Acifluorfen 62476-59-9 cancer Proposition 65
cancer Proposition 65
9 Acrylamide 79-06-1 developmental
CERHR
male reproductive
10 Acrylonitrile 107-13-1 cancer Proposition 65
cancer
11 Actinomycin D 50-76-0 Proposition 65
developmental
12 AF-2;[2-(2-furyl)-3-(5-nitro-2-furyl)]acrylamide 3688-53-7 cancer Proposition 65
13 Aflatoxins ---------- cancer Proposition 65
-1-
14 Alachlor 15972-60-8 cancer Proposition 65
Alcoholic beverages, when associated with alcohol
15 ---------- cancer Proposition 65
abuse
16 Aldrin 309-00-2 cancer Proposition 65
17 All-trans retinoic acid Retinoic Acid 302-79-4 developmental Proposition 65
18 Alprazolam 28981-97-7 developmental Proposition 65
developmental
19 Altretamine 645-05-6 Proposition 65
male reproductive
20 Amantadine hydrochloride 665-66-7 developmental Proposition 65
21 Amikacin sulfate 39831-55-5 developmental Proposition 65
22 2-Aminoanthraquinone 117-79-3 cancer Proposition 65
23 p-Aminoazobenzene 60-09-3 cancer Proposition 65
24 o-Aminoazotoluene 97-56-3 cancer Proposition 65
25 4-Aminobiphenyl (4-amino-diphenyl) 92-67-1 cancer Proposition 65
26 1-Amino-2,4-dibromoanthraquinone 81-49-2 cancer Proposition 65
27 3-Amino-9-ethylcarbazole hydrochloride 6109-97-3 cancer Proposition 65
28 2-Aminofluorene 153-78-6 cancer Proposition 65
29 Aminoglutethimide 125-84-8 developmental Proposition 65
30 Aminoglycosides ---------- developmental Proposition 65
31 1-Amino-2-methylanthraquinone 82-28-0 cancer Proposition 65
32 2-Amino-5-(5-nitro-2-furyl)-1,3,4-thiadiazole 712-68-5 cancer Proposition 65
33 4-Amino-2-nitrophenol 4-Amino-2-nitrophenol 119-34-6 cancer Proposition 65
developmental
34 Aminopterin 54-62-6 Proposition 65
female reproductive
developmental
35 Amiodarone hydrochloride 19774-82-4 female reproductive Proposition 65
male reproductive
36 Amitraz 33089-61-1 developmental Proposition 65
37 Amitrole 61-82-5 cancer Proposition 65
38 Amoxapine 14028-44-5 developmental Proposition 65
39 Amphetamine 300-62-9 developmental CERHR
40 Amsacrine 51264-14-3 cancer IARC
female reproductive
Proposition 65
41 Anabolic steroids ---------- male reproductive
cancer IARC

-2-
42 Analgesic mixtures containing Phenacetin ---------- cancer Proposition 65
43 Angiotensin converting enzyme (ACE) inhibitors ---------- developmental Proposition 65
44 Aniline 62-53-3 cancer Proposition 65
45 Aniline hydrochloride 142-04-1 cancer Proposition 65
46 o-Anisidine 90-04-0 cancer Proposition 65
47 o-Anisidine hydrochloride 134-29-2 cancer Proposition 65
48 Anisindione 117-37-3 developmental Proposition 65
49 Antimony oxide (Antimony trioxide) 1309-64-4 cancer Proposition 65
50 Aramite 140-57-8 cancer Proposition 65
51 Areca nut ---------- cancer Proposition 65
52 Aristolochic acids ---------- cancer Proposition 65
53 Arsenic (inorganic arsenic compounds) ---------- cancer Proposition 65
54 Arsenic (inorganic oxides) ---------- developmental Proposition 65
55 Asbestos 1332-21-4 cancer Proposition 65

Aspirin (NOTE: It is especially important not to use

developmental
aspirin during the last three months of pregnancy,
56 unless specifically directed to do so by a physician 50-78-2 Proposition 65
because it may cause problems in the unborn child
female reproductive
or complications during delivery.)

57 Atenolol 29122-68-7 developmental Proposition 65

58 Auramine 492-80-8 cancer Proposition 65
59 Auranofin 34031-32-8 developmental Proposition 65
60 Azacitidine 320-67-2 cancer Proposition 65
61 Azaserine 115-02-6 cancer Proposition 65
cancer
62 Azathioprine 446-86-6 Proposition 65
developmental
63 Aziridine 151-56-4 cancer IARC
64 Azobenzene 103-33-3 cancer Proposition 65
65 AZT (Zidovudine) 30516-87-1 cancer IARC
66 Barbiturates ---------- developmental Proposition 65
67 Beclomethasone dipropionate 5534-09-8 developmental Proposition 65
developmental
68 Benomyl 17804-35-2 Proposition 65
male reproductive
69 Benthiavalicarb-isopropyl 177406-68-7 cancer EPA
70 Benzal chloride 98-87-3 cancer IARC

-3-
71 Benz[j]aceanthrylene 202-33-5 cancer IARC
72 Benz[a]anthracene 56-55-3 cancer Proposition 65
cancer
73 Benzene 71-43-2 developmental Proposition 65
male reproductive
74 Benzidine [and its salts] 92-87-5 cancer Proposition 65
75 Benzidine-based dyes ---------- cancer Proposition 65
76 Benzodiazepines ---------- developmental Proposition 65
77 Benzo[b]fluoranthene 205-99-2 cancer Proposition 65
78 Benzo[j]fluoranthene 205-82-3 cancer Proposition 65
79 Benzo[k]fluoranthene 207-08-9 cancer Proposition 65
80 Benzofuran 271-89-6 cancer Proposition 65
81 Benzo[c]phenanthrene 195-19-7 cancer IARC
82 Benzo[a]pyrene 50-32-8 cancer Proposition 65
83 Benzotrichloride 98-07-7 cancer Proposition 65
Benzoyl chloride combined with α-chlorinated
84 ---------- cancer IARC
toluene
85 Benzphetamine hydrochloride 5411-22-3 developmental Proposition 65
86 Benzyl chloride 100-44-7 cancer Proposition 65
87 Benzyl violet 4B 1694-09-3 cancer Proposition 65
88 Beryllium and beryllium compounds 7440-41-7 cancer Proposition 65
89 Betel quid with tobacco ---------- cancer Proposition 65
90 Betel quid without tobacco ---------- cancer Proposition 65
91 2,2-Bis(bromomethyl)-1,3-propanediol 3296-90-0 cancer Proposition 65
92 Bis(2-chloroethyl)ether 111-44-4 cancer Proposition 65
N,N-Bis(2-chloroethyl)-2-naphthylamine
93 494-03-1 cancer Proposition 65
(Chlornapazine)
cancer
94 Bischloroethyl nitrosourea (BCNU) (Carmustine) 154-93-8 Proposition 65
developmental
95 Bis(chloromethyl)ether 542-88-1 cancer Proposition 65
96 Bis(2-chloro-1-methylethyl)ether, technical grade ---------- cancer Proposition 65
97 Bitumens, extracts of steam-refined and air refined ---------- cancer Proposition 65
98 Bleomycins 11056-06-7 cancer IARC
99 Bracken fern ---------- cancer Proposition 65
developmental
100 Bromacil lithium salt 53404-19-6 Proposition 65
male reproductive
-4-
101 Bromate 15541-45-4 cancer Proposition 65
102 Bromodichloromethane 75-27-4 cancer Proposition 65
103 Bromoethane 74-96-4 cancer Proposition 65
104 Bromoform 75-25-2 cancer Proposition 65
developmental
105 1-Bromopropane 106-94-5 female reproductive Proposition 65
male reproductive
female reproductive
106 2-Bromopropane 75-26-3 Proposition 65
male reproductive
107 Bromoxynil 1689-84-5 developmental Proposition 65
108 Bromoxynil octanoate 1689-99-2 developmental Proposition 65
109 Butabarbital sodium 143-81-7 developmental Proposition 65
cancer IARC
cancer
110 1,3-Butadiene 106-99-0 developmental
Proposition 65
female reproductive
male reproductive
cancer
111 1,4-Butanediol dimethanesulfonate (Busulfan) 55-98-1 Proposition 65
developmental
112 Butylated hydroxyanisole BHA 25013-16-5 cancer Proposition 65
developmental Proposition 65
113 Butyl benzyl phthalate (BBP) Butyl benzyl phthalate 85-68-7
male reproductive CERHR
114 beta-Butyrolactone 3068-88-0 cancer Proposition 65
115 Cacodylic acid 75-60-5 cancer Proposition 65
developmental
116 Cadmium 7440-43-9 Proposition 65
male reproductive
117 Cadmium and cadmium compounds 7440-43-10 cancer Proposition 65
118 Caffeic acid Caffeic acid 331-39-5 cancer Proposition 65
119 Captafol 2425-06-1 cancer Proposition 65
120 Captan Captan 133-06-2 cancer Proposition 65
121 Carbamazepine 298-46-4 developmental Proposition 65
122 Carbazole 86-74-8 cancer Proposition 65
123 Carbaryl 63-25-2 cancer EPA
Carbon black (airborne, unbound particles of
124 Black 2 1333-86-4 cancer Proposition 65
respirable size)

-5-
 developmental
125 Carbon disulfide 75-15-0 female reproductive Proposition 65
male reproductive
126 Carbon monoxide 630-08-0 developmental Proposition 65
127 Carbon tetrachloride 56-23-5 cancer Proposition 65
128 Carbon-black extracts ---------- cancer Proposition 65
129 Carboplatin 41575-94-4 developmental Proposition 65
130 N-Carboxymethyl-N-nitrosourea 60391-92-6 cancer Proposition 65
131 Catechol Pryocatechol 120-80-9 cancer Proposition 65
132 Ceramic fibers (airborne particles of respirable size) ---------- cancer Proposition 65
133 Certain combined chemotherapy for lymphomas ---------- cancer Proposition 65
134 Chenodiol 474-25-9 developmental Proposition 65
cancer
135 Chlorambucil 305-03-3 Proposition 65
developmental
136 Chloramphenicol 56-75-7 cancer Proposition 65
137 Chlorcyclizine hydrochloride 1620-21-9 developmental Proposition 65
138 Chlordane 57-74-9 cancer Proposition 65
cancer
139 Chlordecone (Kepone) 143-50-0 Proposition 65
developmental
140 Chlordiazepoxide 58-25-3 developmental Proposition 65
141 Chlordiazepoxide hydrochloride 438-41-5 developmental Proposition 65
142 Chlordimeform 6164-98-3 cancer Proposition 65
143 Chlorendic acid 115-28-6 cancer Proposition 65
Chlorinated paraffins (Average chain length,
144 108171-26-2 cancer Proposition 65
C12;approximately 60 percent chlorine by weight)
145 p-Chloroaniline 106-47-8 cancer Proposition 65
146 p-Chloroaniline hydrochloride 20265-96-7 cancer Proposition 65
147 Chloroethane (Ethyl chloride) 75-00-3 cancer Proposition 65
1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) cancer
148 13010-47-4 Proposition 65
(Lomustine) developmental
1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-
149 13909-09-6 cancer Proposition 65
nitrosourea (Methyl-CCNU)
150 Chloroform Chloroform 67-66-3 cancer Proposition 65
151 Chloromethyl methyl ether (technical grade) 107-30-2 cancer Proposition 65
152 3-Chloro-2-methylpropene 563-47-3 cancer Proposition 65
153 1-Chloro-4-nitrobenzene 100-00-5 cancer Proposition 65
-6-
154 4-Chloro-o-phenylenediamine 95-83-0 cancer Proposition 65
155 Chloroprene 126-99-8 cancer Proposition 65
156 Chlorothalonil 1897-45-6 cancer Proposition 65
157 p-Chloro-o-toluidine 95-69-2 cancer Proposition 65
158 p-Chloro-o-toluidine, strong acid salts of ---------- cancer Proposition 65
159 5-Chloro-o-toluidine and its strong acid salts 95-79-4 cancer Proposition 65
160 Chlorotrianisene 569-57-3 cancer Proposition 65
161 Chlorozotocin 54749-90-5 cancer Proposition 65
developmental
162 Chlorsulfuron 64902-72-3 female reproductive Proposition 65
male reproductive
cancer EPA
cancer
163 Chromium (hexavalent compounds) ---------- developmental
Proposition 65
female reproductive
male reproductive
164 Chrysene 218-01-9 cancer Proposition 65
165 C.I. Acid Red 114 6459-94-5 cancer Proposition 65
166 C.I. Basic Red 9 monohydrochloride 569-61-9 cancer Proposition 65
167 C.I. Direct Blue 15 2429-74-5 cancer Proposition 65
168 C.I. Direct Blue 218 28407-37-6 cancer Proposition 65
169 C.I. Solvent Yellow 14 842-07-9 cancer Proposition 65
59865-13-3
170 Ciclosporin (Cyclosporin A; Cyclosporine) cancer Proposition 65
79217-60-0
cancer
developmental
171 Cidofovir 113852-37-2 Proposition 65
female reproductive
male reproductive
172 Cinnamyl anthranilate 87-29-6 cancer Proposition 65
173 Cisplatin 15663-27-1 cancer Proposition 65
174 Citrus Red No. 2 6358-53-8 cancer Proposition 65
175 Cladribine 4291-63-8 developmental Proposition 65
176 Clarithromycin 81103-11-9 developmental Proposition 65
developmental
177 Clobetasol propionate 25122-46-7 Proposition 65
female reproductive

-7-
178 Clofibrate 637-07-0 cancer Proposition 65
179 Clomiphene citrate 50-41-9 developmental Proposition 65
180 Clorazepate dipotassium 57109-90-7 developmental Proposition 65
IARC (under P65 as
181 Coal tars ---------- cancer soots, tars and
mineral oils)
182 Cobalt metal powder 744048-4 cancer Proposition 65
183 Cobalt [II] oxide 1307-96-6 cancer Proposition 65
184 Cobalt sulfate 10124-43-3 cancer Proposition 65
185 Cobalt sulfate heptahydrate 10026-24-1 cancer Proposition 65
developmental
186 Cocaine 50-36-2 Proposition 65
female reproductive
187 Cocamide diethanolamine Cocamide DEA 68603-42-9 cancer EPA
188 Codeine phosphate 52-28-8 developmental Proposition 65
189 Coffee ---------- cancer IARC
190 Coke oven emissions ---------- cancer Proposition 65
developmental
191 Colchicine 64-86-8 Proposition 65
male reproductive
cancer
192 Conjugated estrogens ---------- Proposition 65
developmental
193 Creosotes ---------- cancer Proposition 65
194 p-Cresidine 120-71-8 cancer Proposition 65
195 Cupferron 135-20-6 cancer Proposition 65
196 Cyanazine 21725-46-2 developmental Proposition 65
197 Cycasin 14901-08-7 cancer Proposition 65
198 Cycloate 1134-23-2 developmental Proposition 65
199 Cycloheximide 66-81-9 developmental Proposition 65
200 Cyclopenta[cd]pyrene 27208-37-3 cancer IARC
cancer
developmental
201 Cyclophosphamide (anhydrous) 50-18-0 Proposition 65
female reproductive
male reproductive
cancer
developmental
202 Cyclophosphamide (hydrated) 6055-19-2 Proposition 65
female reproductive
male reproductive

-8-
203 Cyhexatin 13121-70-5 developmental Proposition 65
204 Cyproconazole 94361-06-5 cancer EPA
205 Cytarabine 147-94-4 developmental Proposition 65
206 Cytembena 21739-91-3 cancer Proposition 65
207 D&C Orange No. 17 Daidai203 3468-63-1 cancer Proposition 65
208 D&C Red No. 8 Aka203 2092-56-0 cancer Proposition 65
209 D&C Red No. 9 Aka204 5160-02-1 cancer Proposition 65
210 D&C Red No. 19 Aka213 81-88-9 cancer Proposition 65
cancer
211 Dacarbazine 4342-03-4 Proposition 65
developmental
212 Daminozide 1596-84-5 cancer Proposition 65
213 Danazol 17230-88-5 developmental Proposition 65
214 Dantron (Chrysazin; 1,8-Dihydroxyanthraquinone) 117-10-2 cancer Proposition 65
215 Daunomycin 20830-81-3 cancer Proposition 65
216 Daunorubicin hydrochloride 23541-50-6 developmental Proposition 65
217 2,4-D butyric acid 94-82-6 male reproductive Proposition 65
218 DDD (Dichlorodiphenyl-dichloroethane) 72-54-8 cancer Proposition 65
219 DDE (Dichlorodiphenyl-dichloroethylene) 72-55-9 cancer Proposition 65
220 DDT (Dichlorodiphenyl-trichloroethane) 50-29-3 cancer Proposition 65
developmental
221 o,p'-DDT 789-02-6 female reproductive Proposition 65
male reproductive
developmental
222 p,p'-DDT 50-29-3 female reproductive Proposition 65
male reproductive
223 DDVP (Dichlorvos) 62-73-7 cancer Proposition 65
224 N,N'-Diacetylbenzidine 613-35-4 cancer Proposition 65
225 2,4-Diaminoanisole 615-05-4 cancer Proposition 65
226 2,4-Diaminoanisole sulfate 39156-41-7 cancer Proposition 65
227 4,4'-Diaminodiphenyl ether (4,4'-Oxydianiline) 101-80-4 cancer Proposition 65
228 2,4-Diaminotoluene 95-80-7 cancer Proposition 65
229 Demeclocycline hydrochloride (internal use) 64-73-3 developmental Proposition 65
230 Diaminotoluene (mixed) ---------- cancer Proposition 65
231 Diazepam 439-14-5 developmental Proposition 65
232 Diazoaminobenzene 136-35-6 cancer Proposition 65

-9-
233 Diazoxide 364-98-7 developmental Proposition 65
234 Dibenz[a,h]acridine 226-36-8 cancer Proposition 65
235 Dibenz[a,j]acridine 224-42-0 cancer Proposition 65
236 Dibenz[a,h]anthracene 53-70-3 cancer Proposition 65
237 7H-Dibenzo[c,g]carbazole 194-59-2 cancer Proposition 65
238 Dibenzo[a,e]pyrene 192-65-4 cancer Proposition 65
239 Dibenzo[a,h]pyrene 189-64-0 cancer Proposition 65
240 Dibenzo[a,i]pyrene 189-55-9 cancer Proposition 65
241 Dibenzo[a,l]pyrene 191-30-0 cancer Proposition 65
cancer
242 1,2-Dibromo-3-chloropropane (DBCP) 96-12-8 Proposition 65
male reproductive
243 2,3-Dibromo-1-propanol 96-13-9 cancer Proposition 65
244 Dichloroacetic acid 79-43-6 cancer Proposition 65
245 p-Dichlorobenzene 106-46-7 cancer Proposition 65
246 3,3'-Dichlorobenzidine 91-94-1 cancer Proposition 65
247 3,3'-Dichlorobenzidine dihydrochloride 612-83-9 cancer Proposition 65
248 1,4-Dichloro-2-butene 764-41-0 cancer Proposition 65
249 3,3'-Dichloro-4,4'-diamino-diphenyl ether 28434-86-8 cancer Proposition 65
250 1,1-Dichloroethane 75-34-3 cancer Proposition 65
251 Dichloromethane (Methylene chloride) 75-09-2 cancer Proposition 65
252 Dichlorophene Dichlorophene 97-23-4 developmental Proposition 65
253 Dichlorphenamide 120-97-8 developmental Proposition 65
254 Diclofop methyl 51338-27-3 developmental Proposition 65
255 1,2-Dichloropropane 78-87-5 cancer Proposition 65
256 1,3-Dichloropropene 542-75-6 cancer Proposition 65
257 Diclofop-methyl 51338-27-3 cancer EPA
258 Dicumarol 66-76-2 developmental Proposition 65
259 Dieldrin 60-57-1 cancer Proposition 65
260 Dienestrol 84-17-3 cancer Proposition 65
261 Diepoxybutane 1464-53-5 cancer Proposition 65
262 Diesel engine exhaust ---------- cancer Proposition 65
263 Diesel fuel, marine ---------- cancer IARC
developmental
264 Di-n-butyl phthalate (DBP) Dibutyl phthalate 84-74-2 female reproductive Proposition 65
male reproductive

- 10 -
 cancer
265 Di(2-ethylhexyl)phthalate Diethylhexyl phthalate 117-81-7 developmental Proposition 65
male reproductive
female reproductive
266 Di-n-hexyl phthalate (DnHP) 84-75-3 Proposition 65
male reproductive
267 1,2-Diethylhydrazine 1615-80-1 cancer Proposition 65
cancer
268 Diethylstilbestrol (DES) 56-53-1 Proposition 65
developmental
269 Diethyl sulfate 64-67-5 cancer Proposition 65
developmental
270 Diflunisal 22494-42-4 Proposition 65
female reproductive
271 Diglycidyl resorcinol ether (DGRE) 101-90-6 cancer Proposition 65
272 Dihydroergotamine mesylate 6190-39-2 developmental Proposition 65
273 Dihydrosafrole 94-58-6 cancer Proposition 65
68515-49-1
274 Di-isodecyl phthalate (DIDP) developmental CERHR
26761-40-0
275 Diisononylphthalate 28553-12-0 developmental CERHR
276 Diisopropyl sulfate 2973-10-6 cancer Proposition 65
277 Diltiazem hydrochloride 33286-22-5 developmental Proposition 65
278 3,3'-Dimethoxybenzidine (o-Dianisidine) 119-90-4 cancer Proposition 65
279 3,3'-Dimethoxybenzidine dihydrochloride 20325-40-0 cancer Proposition 65
3,3'-Dimethoxybenzidine-based dyes metabolized to
280 ---------- cancer Proposition 65
3,3'-dimethoxybenzidine
281 4-Dimethylaminoazobenzene 60-11-7 cancer Proposition 65
trans-2-[(Dimethylamino)methylimino]-5-[2-(5-nitro-2-
282 55738-54-0 cancer Proposition 65
furyl)vinyl]-1,3,4-oxadiazole
283 7,12-Dimethylbenz(a)anthracene 57-97-6 cancer Proposition 65
284 3,3'-Dimethylbenzidine (ortho-Tolidine) 119-93-7 cancer Proposition 65
285 3,3'-Dimethylbenzidine dihydrochloride 612-82-8 cancer Proposition 65
3,3'-Dimethylbenzidine-based dyes metabolized to
286 ---------- cancer Proposition 65
3,3'-dimethylbenzidine
287 Dimethylcarbamoyl chloride 79-44-7 cancer Proposition 65
288 1,1-Dimethylhydrazine (UDMH) 57-14-7 cancer Proposition 65
289 1,2-Dimethylhydrazine 540-73-8 cancer Proposition 65
290 Dimethyl sulfate 77-78-1 cancer Proposition 65

- 11 -
291 Dimethylvinylchloride 513-37-1 cancer Proposition 65
292 m-Dinitrobenzene 99-65-0 male reproductive Proposition 65
293 o-Dinitrobenzene 528-29-0 male reproductive Proposition 65
294 p-Dinitrobenzene 100-25-4 male reproductive Proposition 65
295 3,7-Dinitrofluoranthene 105735-71-5 cancer Proposition 65
296 3,9-Dinitrofluoranthene 22506-53-2 cancer Proposition 65
297 1,6-Dinitropyrene 42397-64-8 cancer Proposition 65
298 1,8-Dinitropyrene 42397-65-9 cancer Proposition 65
female reproductive
299 Dinitrotoluene (technical grade) ---------- Proposition 65
male reproductive
300 Dinitrotoluene mixture, 2,4-/2,6- ---------- cancer Proposition 65
cancer
301 2,4-Dinitrotoluene 121-14-2 Proposition 65
male reproductive
cancer
302 2,6-Dinitrotoluene 606-20-2 Proposition 65
male reproductive
303 Dinocap 39300-45-3 developmental Proposition 65
developmental
304 Dinoseb 88-85-7 Proposition 65
male reproductive
305 1,4-Dioxane 123-91-1 cancer Proposition 65
cancer
306 Diphenylhydantoin (Phenytoin) 57-41-0 Proposition 65
developmental
307 Diphenylhydantoin (Phenytoin), sodium salt 630-93-3 cancer Proposition 65
308 Di-n-propyl isocinchomeronate (MGK Repellent 326) Dipropyl Pyridinedicarboxylate 136-45-8 cancer Proposition 65
309 Direct Black 38 (technical grade) 1937-37-7 cancer Proposition 65
310 Direct Blue 6 (technical grade) 2602-46-2 cancer Proposition 65
311 Direct Brown 95 (technical grade) 16071-86-6 cancer Proposition 65
312 Disodium cyanodithioimidocarbonate 138-93-2 developmental Proposition 65
313 Disperse Blue 1 Disperse Blue 1 2475-45-8 cancer Proposition 65
314 Diuron 330-54-1 cancer Proposition 65
cancer
315 Doxorubicin hydrochloride (Adriamycin) 25316-40-9 developmental Proposition 65
male reproductive
316 Doxycycline (internal use) 564-25-0 developmental Proposition 65
317 Doxycycline calcium (internal use) 94088-85-4 developmental Proposition 65
318 Doxycycline hyclate (internal use) 24390-14-5 developmental Proposition 65

- 12 -
319 Doxycycline monohydrate (internal use) 17086-28-1 developmental Proposition 65
320 Endrin 72-20-8 developmental Proposition 65
321 Environmental tobacco smoke (ETS) ---------- developmental Proposition 65
cancer
322 Epichlorohydrin 106-89-8 Proposition 65
male reproductive
323 Epoxiconazole 135319-73-2 cancer EPA
324 1,2-Epoxybutane 106-88-7 cancer IARC
325 Ergotamine tartrate 379-79-3 developmental Proposition 65
12510-42-8
326 Erionite cancer Proposition 65
66733-21-9
327 Estradiol 17beta Estradiol 50-28-2 cancer Proposition 65
328 Estragole 140-67-0 cancer Proposition 65
329 Estrogens, nonsteroidal ---------- cancer IARC
330 Estrogens, steroidal ---------- cancer Proposition 65
331 Estrone 53-16-7 cancer Proposition 65
cancer
332 Estropipate 7280-37-7 Proposition 65
developmental
333 Ethinylestradiol Ethinylestradiol 57-63-6 cancer Proposition 65
334 Ethionamide 536-33-4 developmental Proposition 65
335 Ethoprop 13194-48-4 cancer Proposition 65
336 Ethyl acrylate Ethyl acrylate 140-88-5 cancer Proposition 65
337 Ethyl alcohol in alcoholic beverages ---------- developmental Proposition 65
338 Ethylbenzene 100-41-4 cancer Proposition 65
339 Ethyl dipropylthiocarbamate 759-94-4 developmental Proposition 65
340 Ethyl-4,4'-dichlorobenzilate 510-15-6 cancer Proposition 65
cancer
341 Ethylene dibromide 106-93-4 developmental Proposition 65
male reproductive
342 Ethylene dichloride (1,2-Dichloroethane) Ethylene dichloride 107-06-2 cancer Proposition 65
343 Ethylene glycol Glycol 107-21-1 developmental CERHR
developmental
344 Ethylene glycol monoethyl ether Ethoxyethanol 110-80-5 Proposition 65
male reproductive
developmental
345 Ethylene glycol monoethyl ether acetate Ethoxyethanol acetate 111-15-9 Proposition 65
male reproductive
developmental
346 Ethylene glycol monomethyl ether Methoxyethanol 109-86-4 Proposition 65
male reproductive
- 13 -
 developmental
347 Ethylene glycol monomethyl ether acetate Methoxyethanol acetate 110-49-6 Proposition 65
male reproductive
348 Ethyleneimine 151-56-4 cancer Proposition 65
cancer IARC
349 Ethylene oxide 75-21-8 cancer
Proposition 65
female reproductive
cancer
350 Ethylene thiourea 96-45-7 Proposition 65
developmental
351 Ethyl methanesulfonate 62-50-0 cancer Proposition 65
developmental
352 Etodolac 41340-25-4 Proposition 65
female reproductive
developmental Proposition 65
353 Etoposide 33419-42-0
cancer IARC
354 Etretinate 54350-48-0 developmental Proposition 65
355 Fenoxaprop ethyl 66441-23-4 developmental Proposition 65
356 Fenoxycarb 72490-01-8 cancer Proposition 65
357 Filgrastim 121181-53-1 developmental Proposition 65
358 Fluazifop butyl 69806-50-4 developmental Proposition 65
developmental
359 Flunisolide 3385-03-3 Proposition 65
female reproductive
360 Fluorouracil 51-21-8 developmental Proposition 65
developmental
361 Fluoxetine 54910-89-3 male reproductive CERHR
female reproductive
59333-67-4 developmental
362 Fluoxetine hydrochloride (Prozac) male reproductive CERHR
56296-78-7
female reproductive
363 Fluoxymesterone 76-43-7 developmental Proposition 65
364 Flurazepam hydrochloride 1172-18-5 developmental Proposition 65
developmental
365 Flurbiprofen 5104-49-4 Proposition 65
female reproductive
366 Flutamide 13311-84-7 developmental Proposition 65
367 Fluticasone propionate 80474-14-2 developmental Proposition 65
368 Fluvalinate 69409-94-5 developmental Proposition 65
369 Folpet 133-07-3 cancer Proposition 65

- 14 -
370 Formaldehyde (gas) Formaldehyde 50-00-0 cancer Proposition 65
371 2-(2-Formylhydrazino)-4-(5-nitro-2-furyl)thiazole 3570-75-0 cancer Proposition 65
372 Fuel oils, residual (heavy) ---------- cancer IARC
373 Fumonisin B1 116355-83-0 cancer Proposition 65
374 Furan 110-00-9 cancer Proposition 65
375 Furazole (Mon 13900) 121776-33-8 cancer EPA
376 Furazolidone 67-45-8 cancer Proposition 65
377 Furmecyclox 60568-05-0 cancer Proposition 65
378 Fusarin C 79748-81-5 cancer Proposition 65
IARC (under P65 as
379 Gallium arsenide 1303-00-0 cancer inorganic arsenic
compounds)
82410-32-0 cancer
380 Ganciclovir sodium developmental Proposition 65
107910-75-8
male reproductive
381 Gasoline ---------- cancer IARC
382 Gasoline engine exhaust (condensates/extracts) ---------- cancer Proposition 65
cancer
383 Gemfibrozil 25812-30-0 female reproductive Proposition 65
male reproductive
developmental
384 Genistein (purified) ---------- female reproductive CERHR
male reproductive
Glasswool fibers (airborne particles of respirable
385 ---------- cancer Proposition 65
size)
Glu-P-1 (2-Amino-6-methyldipyrido[1,2- a:3',2'-
386 67730-11-4 cancer Proposition 65
d]imidazole)
387 Glu-P-2 (2-Aminodipyrido[1,2-a:3',2'-d]imidazole) 67730-10-3 cancer Proposition 65
388 Glycidaldehyde 765-34-4 cancer Proposition 65
389 Glycidol 556-52-5 cancer Proposition 65
developmental
390 Goserelin acetate 65807-02-5 female reproductive Proposition 65
male reproductive
391 Griseofulvin 126-07-8 cancer Proposition 65

392 Gyromitrin (Acetaldehyde methylformylhydrazone) 16568-02-8 cancer Proposition 65

- 15 -
393 Halazepam 23092-17-3 developmental Proposition 65
Proposition 65
394 Halobetasol propionate 66852-54-8 developmental
8/20/1999
developmental Proposition 65
395 Haloperidol 52-86-8
female reproductive 1/29/1999
Proposition 65
396 Halothane 151-67-7 developmental
9/1/1996
397 Haloxyfop-methyl (Verdict) 69806-40-2 cancer EPA
398 HC Blue 1 2784-94-3 cancer Proposition 65
cancer
399 Heptachlor 76-44-8 Proposition 65
developmental
400 Heptachlor epoxide 1024-57-3 cancer Proposition 65
Herbal remedies containing plant species of the
401 ---------- cancer Proposition 65
genus Aristolochia
cancer
402 Hexachlorobenzene 118-74-1 Proposition 65
developmental
403 Hexachlorocyclohexane (technical grade) ---------- cancer Proposition 65
404 Hexachlorodibenzodioxin 34465-46-8 cancer Proposition 65
405 Hexachloroethane 67-72-1 cancer Proposition 65
2,4-Hexadienal (89% trans, trans isomer; 11% cis,
406 ---------- cancer Proposition 65
trans isomer)
cancer
407 Hexamethylphosphoramide 680-31-9 Proposition 65
male reproductive
408 Histrelin acetate ---------- developmental Proposition 65
developmental
409 Hydramethylnon 67485-29-4 Proposition 65
male reproductive
410 Hydrazine 302-01-2 cancer Proposition 65
411 Hydrazine sulfate 10034-93-2 cancer Proposition 65
412 Hydrazobenzene (1,2-Diphenylhydrazine) 122-66-7 cancer Proposition 65
413 1-Hydroxyanthraquinone 129-43-1 cancer Proposition 65
developmental Proposition 65
414 Hydroxyurea 127-07-1 female reproductive
CERHR
male reproductive
developmental
415 Idarubicin hydrochloride 57852-57-0 Proposition 65
male reproductive
416 Ifosfamide 3778-73-2 developmental Proposition 65

- 16 -
417 Iodine-131 10043-66-0 developmental Proposition 65
418 Imazalil 35554-44-0 cancer EPA
419 Indeno [1,2,3-cd]pyrene 193-39-5 cancer Proposition 65
420 Indium phosphide 22398-80-7 cancer Proposition 65
421 IQ (2-Amino-3-methylimidazo[4,5-f] quinoline) 76180-96-6 cancer Proposition 65
422 Iprodione 36734-19-7 cancer Proposition 65
140923-17-7
423 Iprovalicarb cancer EPA
140923-25-7
424 Iron dextran complex 9004-66-4 cancer Proposition 65
425 Isobutyl nitrite 542-56-3 cancer Proposition 65
426 Isoprene 78-79-5 cancer Proposition 65
427 Isotretinoin 4759-48-2 developmental Proposition 65
428 Isoxaflutole 141112-29-0 cancer Proposition 65
429 Kresoxim-methyl 143390-89-0 cancer EPA
430 Lactofen 77501-63-4 cancer Proposition 65
431 Lasiocarpine 303-34-4 cancer Proposition 65
developmental
432 Lead 7439-92-1 female reproductive Proposition 65
male reproductive
433 Lead and lead compounds 7439-92-1 cancer Proposition 65
434 Lead acetate Lead acetate 301-04-2 cancer Proposition 65
435 Lead phosphate 7446-27-7 cancer Proposition 65
436 Lead subacetate 1335-32-6 cancer Proposition 65
developmental
437 Leuprolide acetate 74381-53-6 female reproductive Proposition 65
male reproductive
438 Levodopa 59-92-7 developmental Proposition 65
439 Levonorgestrel implants 797-63-7 female reproductive Proposition 65
440 Lindane and other hexachlorocyclohexane isomers ---------- cancer Proposition 65
441 Linuron 330-55-2 developmental Proposition 65
442 Lithium carbonate 554-13-2 developmental Proposition 65
443 Lithium citrate 919-16-4 developmental Proposition 65
444 Lorazepam 846-49-1 developmental Proposition 65
445 Lovastatin 75330-75-5 developmental Proposition 65
446 Lynestrenol 52-76-6 cancer Proposition 65

- 17 -
447 Mancozeb 8018-01-7 cancer Proposition 65
448 Maneb 12427-38-2 cancer Proposition 65
449 Marijuana smoke ---------- cancer Proposition 65
Me-A-alpha-C (2-Amino-3-methyl-9H-pyrido[2,3-
450 68006-83-7 cancer Proposition 65
b]indole)
451 Mebendazole 31431-39-7 developmental Proposition 65
cancer
452 Medroxyprogesterone acetate 71-58-9 Proposition 65
developmental
453 Megestrol acetate 595-33-5 developmental Proposition 65
454 MeIQ (2-Amino-3,4-dimethylimidazo[4,5-f]quinoline) 77094-11-2 cancer Proposition 65
MeIQx (2-Amino-3,8-dimethylimidazo[4,5-
455 77500-04-0 cancer Proposition 65
f]quinoxaline)
cancer
456 Melphalan 148-82-3 Proposition 65
developmental
457 Menotropins 9002-68-0 developmental Proposition 65
458 Mepanipyrim 110235-47-7 cancer EPA
459 Meprobamate 57-53-4 developmental Proposition 65
460 Mercaptopurine 6112-76-1 developmental Proposition 65
461 Mercury and mercury compounds 7439-97-6 developmental Proposition 65
462 Merphalan 531-76-0 cancer Proposition 65
463 Mestranol 72-33-3 cancer Proposition 65
464 Methacycline hydrochloride 3963-95-9 developmental Proposition 65
cancer
465 Metham sodium 137-42-8 Proposition 65
developmental
466 Methamphetamine 537-46-2 developmental CERHR
467 Methanol Methyl alcohol 67-56-1 developmental CERHR
468 Methazole 20354-26-1 developmental Proposition 65
469 Methimazole 60-56-0 developmental Proposition 65
470 Methotrexate 59-05-2 developmental Proposition 65
471 Methotrexate sodium 15475-56-6 developmental Proposition 65
472 5-Methoxypsoralen with ultraviolet A therapy 484-20-8 cancer Proposition 65
473 8-Methoxypsoralen with ultraviolet A therapy 298-81-7 cancer Proposition 65
474 2-Methylaziridine (Propyleneimine) 75-55-8 cancer Proposition 65
475 Methylazoxymethanol 590-96-5 cancer Proposition 65
476 Methylazoxymethanol acetate 592-62-1 cancer Proposition 65

- 18 -
477 Methyl bromide, as a structural fumigant 74-83-9 developmental Proposition 65
478 Methyl carbamate 598-55-0 cancer Proposition 65
479 Methyl chloride 74-87-3 developmental Proposition 65
480 3-Methylcholanthrene 56-49-5 cancer Proposition 65
481 5-Methylchrysene 3697-24-3 cancer Proposition 65
482 4,4'-Methylene bis(2-chloroaniline) 101-14-4 cancer Proposition 65
483 4,4'-Methylene bis(N,N-dimethyl)benzenamine 101-61-1 cancer Proposition 65
484 4,4'-Methylene bis(2-methylaniline) 838-88-0 cancer Proposition 65
485 Methylene bis (thiocyanate) 6317-18-6 cancer EPA
486 4,4'-Methylenedianiline 101-77-9 cancer Proposition 65
487 4,4'-Methylenedianiline dihydrochloride 13552-44-8 cancer Proposition 65
488 Methyleugenol Methyl eugenol 93-15-2 cancer Proposition 65
489 Methylhydrazine and its salts 60-34-3 cancer Proposition 65
490 Methyl iodide 74-88-4 cancer Proposition 65
491 Methyl isothiocyanate 556-61-6 cancer EPA
492 Methyl mercury 22967-92-6 developmental Proposition 65
493 Methylmercury compounds ---------- cancer Proposition 65
494 Methyl methanesulfonate 66-27-3 cancer Proposition 65
495 2-Methyl-1-nitroanthraquinone (of uncertain purity) 129-15-7 cancer Proposition 65
496 N-Methyl-N'-nitro-N-nitrosoguanidine 70-25-7 cancer Proposition 65
497 N-Methylolacrylamide 924-42-5 cancer Proposition 65
498 N-Methylpyrrolidone Methyl pyrrolidone 872-50-4 developmental Proposition 65
499 Methyltestosterone 58-18-4 developmental Proposition 65
500 Methylthiouracil 56-04-2 cancer Proposition 65
cancer
501 Metiram 9006-42-2 Proposition 65
developmental
502 Metronidazole 443-48-1 cancer Proposition 65
503 Michler's ketone 90-94-8 cancer Proposition 65
504 Microcystin-LR ---------- cancer IARC
505 Midazolam hydrochloride 59467-96-8 developmental Proposition 65
IARC (under P65 as
506 Mineral oils, untreated and mildly treated ---------- cancer soots, tars and
mineral oils)
507 Minocycline hydrochloride (internal use) 13614-98-7 developmental Proposition 65
508 Mirex 2385-85-5 cancer Proposition 65

- 19 -
509 Misoprostol 59122-46-2 developmental Proposition 65
510 Mitomycin C 50-07-7 cancer Proposition 65
developmental Proposition 65
511 Mitoxantrone hydrochloride 70476-82-3
cancer IARC
MON 4660 (4-(dichloroacetyl)-1-oxa-4-
512 71526-07-3 cancer EPA
azaspiro[4.5]decane)
513 Monocrotaline 315-22-0 cancer Proposition 65
5-(Morpholinomethyl)-3-[(5-nitrofurfurylidene)-amino]-
514 139-91-3 cancer Proposition 65
2-oxazolidinone
515 Mustard Gas 505-60-2 cancer Proposition 65
MX (3-chloro-4-dichloromethyl-5-hydroxy-2(5H)-
516 77439-76-0 cancer Proposition 65
furanone)
developmental
517 Myclobutanil 88671-89-0 Proposition 65
male reproductive
518 Nabam 142-59-6 developmental Proposition 65
519 Nafarelin acetate 86220-42-0 developmental Proposition 65
520 Nafenopin 3771-19-5 cancer Proposition 65
521 Nalidixic acid 389-08-2 cancer Proposition 65
522 Naphthalene 91-20-3 cancer Proposition 65
523 1-Naphthylamine 134-32-7 cancer Proposition 65
524 2-Naphthylamine 91-59-8 cancer Proposition 65
525 Neomycin sulfate (internal use) 1405-10-3 developmental Proposition 65
526 Netilmicin sulfate 56391-57-2 developmental Proposition 65
527 Nickel (Metallic) 7440-02-0 cancer Proposition 65
528 Nickel acetate 373-02-4 cancer Proposition 65
529 Nickel carbonate 3333-67-3 cancer Proposition 65
cancer
530 Nickel carbonyl 13463-39-3 Proposition 65
developmental
531 Nickel compounds ---------- cancer Proposition 65
12054-48-7
532 Nickel hydroxide cancer Proposition 65
12125-56-3
533 Nickelocene 1271-28-9 cancer Proposition 65
534 Nickel oxide 1313-99-1 cancer Proposition 65
Nickel refinery dust from the pyrometallurgical
535 ---------- cancer Proposition 65
process
536 Nickel subsulfide 12035-72-2 cancer Proposition 65
- 20 -
537 Nicotine 54-11-5 developmental Proposition 65
developmental
538 Nifedipine 21829-25-4 female reproductive Proposition 65
male reproductive
539 Nimodipine 66085-59-4 developmental Proposition 65
540 Niridazole 61-57-4 cancer Proposition 65
cancer
541 Nitrapyrin 1929-82-4 Proposition 65
developmental
Nitrate or nitrite, ingested under conditions that result
542 ---------- cancer IARC
in endogenous nitrosation
543 Nitrilotriacetic acid 139-13-9 cancer Proposition 65
544 Nitrilotriacetic acid trisodium salt monohydrate 18662-53-8 cancer Proposition 65
545 5-Nitroacenaphthene 602-87-9 cancer Proposition 65
546 o-Nitroanisole 91-23-6 cancer Proposition 65
Proposition 65
547 Nitrobenzene 98-95-3 cancer
EPA
548 4-Nitrobiphenyl 92-93-3 cancer Proposition 65
549 6-Nitrochrysene 7496-02-8 cancer Proposition 65
550 Nitrofen (technical grade) 1836-75-5 cancer Proposition 65
551 2-Nitrofluorene 607-57-8 cancer Proposition 65
552 Nitrofurantoin 67-20-9 male reproductive Proposition 65
553 Nitrofurazone 59-87-0 cancer Proposition 65
554 1-[(5-Nitrofurfurylidene)-amino]-2-imidazolidinone 555-84-0 cancer Proposition 65
555 N-[4-(5-Nitro-2-furyl)-2-thiazolyl]acetamide 531-82-8 cancer Proposition 65
cancer
556 Nitrogen mustard (Mechlorethamine) 51-75-2 Proposition 65
developmental
Nitrogen mustard hydrochloride (Mechlorethamine cancer
557 55-86-7 Proposition 65
hydrochloride) developmental
558 Nitrogen mustard N-oxide 126-85-2 cancer Proposition 65
559 Nitrogen mustard N-oxide hydrochloride 302-70-5 cancer Proposition 65
560 Nitromethane Nitromethane 75-52-5 cancer Proposition 65
561 2-Nitropropane 79-46-9 cancer Proposition 65
562 1-Nitropyrene 5522-43-0 cancer Proposition 65
563 4-Nitropyrene 57835-92-4 cancer Proposition 65
564 N-Nitrosodi-n-butylamine 924-16-3 cancer Proposition 65

- 21 -
565 N-Nitrosodiethanolamine 1116-54-7 cancer Proposition 65
566 N-Nitrosodiethylamine 55-18-5 cancer Proposition 65
567 N-Nitrosodimethylamine 62-75-9 cancer Proposition 65
568 p-Nitrosodiphenylamine 156-10-5 cancer Proposition 65
569 N-Nitrosodiphenylamine 86-30-6 cancer Proposition 65
570 N-Nitrosodi-n-propylamine 621-64-7 cancer Proposition 65
571 N-Nitroso-N-ethylurea 759-73-9 cancer Proposition 65
572 3-(N-Nitrosomethylamino) propionitrile 60153-49-3 cancer Proposition 65
573 4-(N-Nitrosomethylamino)-1-(3-pyridyl)1-butanone 64091-91-4 cancer Proposition 65
574 N-Nitrosomethylethylamine 10595-95-6 cancer Proposition 65
575 N-Nitroso-N-methylurea 684-93-5 cancer Proposition 65
576 N-Nitroso-N-methylurethane 615-53-2 cancer Proposition 65
577 N-Nitrosomethylvinylamine 4549-40-0 cancer Proposition 65
578 N-Nitrosomorpholine 59-89-2 cancer Proposition 65
579 N-Nitrosonornicotine 16543-55-8 cancer Proposition 65
580 N-Nitrosopiperidine 100-75-4 cancer Proposition 65
581 N-Nitrosopyrrolidine 930-55-2 cancer Proposition 65
582 N-Nitrososarcosine 13256-22-9 cancer Proposition 65
583 o-Nitrotoluene 88-72-2 cancer Proposition 65
cancer
584 Norethisterone (Norethindrone) 68-22-4 Proposition 65
developmental
585 Norethisterone acetate (Norethindrone acetate) 51-98-9 developmental Proposition 65
586 Norethynodrel 68-23-5 cancer Proposition 65
587 Norgestrel 6533-00-2 developmental Proposition 65
588 Ochratoxin A 303-47-9 cancer Proposition 65
589 Oil Orange SS Daidai403 2646-17-5 cancer Proposition 65
590 Oral contraceptives, combined ---------- cancer Proposition 65
591 Oral contraceptives, sequential ---------- cancer Proposition 65
592 Oryzalin 19044-88-3 cancer EPA
cancer
593 Oxadiazon 19666-30-9 Proposition 65
developmental
cancer
594 Oxazepam 604-75-1 Proposition 65
developmental
female reproductive
595 Oxydemeton methyl 301-12-2 Proposition 65
male reproductive
- 22 -
 cancer
596 Oxymetholone 434-07-1 Proposition 65
developmental
597 Oxytetracycline (internal use) 79-57-2 developmental Proposition 65
598 Oxytetracycline hydrochloride (internal use) 2058-46-0 developmental Proposition 65
cancer
599 Oxythioquinox (Chinomethionat) 2439-01-2 Proposition 65
developmental
developmental
600 Paclitaxel 33069-62-4 female reproductive Proposition 65
male reproductive
601 Palygorskite fibers (> 5mm in length) 12174-11-7 cancer Proposition 65
602 Panfuran S 794-93-4 cancer Proposition 65
603 Paramethadione 115-67-3 developmental Proposition 65
604 Penicillamine 52-67-5 developmental Proposition 65
605 Pentachlorophenol 87-86-5 cancer Proposition 65
606 Pentobarbital sodium 57-33-0 developmental Proposition 65
607 Pentostatin 53910-25-1 developmental Proposition 65
608 Permethrin Permethrin 52645-53-1 cancer EPA
609 Phenacemide 63-98-9 developmental Proposition 65
610 Phenacetin 62-44-2 cancer Proposition 65
611 Phenazopyridine 94-78-0 cancer Proposition 65
612 Phenazopyridine hydrochloride 136-40-3 cancer Proposition 65
613 Phenesterin 3546-10-9 cancer Proposition 65
614 Phenobarbital 50-06-6 cancer Proposition 65
615 Phenolphthalein 77-09-8 cancer Proposition 65
616 Phenoxybenzamine 59-96-1 cancer Proposition 65
617 Phenoxybenzamine hydrochloride 63-92-3 cancer Proposition 65
618 Phenprocoumon 435-97-2 developmental Proposition 65
619 o-Phenylenediamine and its salts 95-54-5 cancer Proposition 65
620 Phenyl glycidyl ether 122-60-1 cancer Proposition 65
621 Phenylhydrazine and its salts 100-63-0 cancer Proposition 65
622 o-Phenylphenate, sodium 132-27-4 cancer Proposition 65
623 o-Phenylphenol 90-43-7 cancer Proposition 65
PhiP(2-Amino-1-methyl-6-phenylimidazol[4,5-
624 105650-23-5 cancer Proposition 65
b]pyridine)
625 Pickled vegetables (traditional in Asia) ---------- cancer IARC

- 23 -
 developmental
626 Pimozide 2062-78-4 Proposition 65
female reproductive
627 Pipobroman 54-91-1 developmental Proposition 65
628 Pirimicarb 23103-98-2 cancer EPA
629 Plicamycin 18378-89-7 developmental Proposition 65
cancer
630 Polybrominated biphenyls ---------- Proposition 65
developmental
cancer
631 Polychlorinated biphenyls ---------- Proposition 65
developmental
Polychlorinated biphenyls (containing 60 or more
632 ---------- cancer Proposition 65
percent chlorine by molecular weight)
633 Polychlorinated dibenzo-p-dioxins ---------- cancer Proposition 65
634 Polychlorinated dibenzofurans ---------- cancer Proposition 65
635 Polygeenan 53973-98-1 cancer Proposition 65
636 Ponceau MX 3761-53-3 cancer Proposition 65
637 Ponceau 3R 3564-09-8 cancer Proposition 65
638 Potassium bromate 7758-01-2 cancer Proposition 65
639 Potassium dimethyldithiocarbamate 128-03-0 developmental Proposition 65
640 Pravastatin sodium 81131-70-6 developmental Proposition 65
641 Prednisolone sodium phosphate 125-02-0 developmental Proposition 65
642 Primidone 125-33-7 cancer Proposition 65
643 Procarbazine 671-16-9 cancer Proposition 65
cancer
644 Procarbazine hydrochloride 366-70-1 Proposition 65
developmental
645 Procymidone 32809-16-8 cancer Proposition 65
646 Progesterone 57-83-0 cancer Proposition 65
647 Pronamide 23950-58-5 cancer Proposition 65
648 Propachlor 1918-16-7 cancer Proposition 65
649 1,3-Propane sultone 1120-71-4 cancer Proposition 65
cancer
650 Propargite 2312-35-8 Proposition 65
developmental
651 beta-Propiolactone 57-57-8 cancer Proposition 65
652 Propoxur 114-26-1 cancer Proposition 65
653 Propylene glycol mono-t-butyl ether 57018-52-7 cancer Proposition 65
654 Propylene oxide 75-56-9 cancer Proposition 65

- 24 -
 cancer
655 Propylthiouracil 51-52-5 Proposition 65
developmental
656 Pyrimethamine 58-14-0 developmental Proposition 65
657 Pymetrozine 123312-89-0 cancer EPA
658 Pyraflufen-ethyl 129630-19-9 cancer EPA
659 Pyridine 110-86-1 cancer Proposition 65
660 Quazepam 36735-22-5 developmental Proposition 65
661 Quinoline and its strong acid salts 91-22-5 cancer Proposition 65
662 Quizalofop-ethyl 76578-14-8 male reproductive Proposition 65
663 Radionuclides ---------- cancer Proposition 65
664 Reserpine 50-55-5 cancer Proposition 65
665 Residual (heavy) fuel oils ---------- cancer Proposition 65
developmental
666 Resmethrin 10453-86-8 Proposition 65
cancer
Retinol/retinyl esters, when in daily dosages in
excess of 10,000 IU, or 3,000 retinol equivalents.
(NOTE: Retinol/retinyl esters are required and
667 ---------- developmental Proposition 65
essential for maintenance of normal reproductive
function. The recommended daily level during
pregnancy is 8,000 IU.)
developmental
668 Ribavirin 36791-04-5 Proposition 65
male reproductive
669 Riddelliine 23246-96-0 cancer Proposition 65
developmental
670 Rifampin 13292-46-1 Proposition 65
female reproductive
671 Safrole 94-59-7 cancer Proposition 65
672 Salted fish (Chinese-style) ---------- cancer IARC
673 Secobarbital sodium 309-43-3 developmental Proposition 65
674 Selenium sulfide 7446-34-6 cancer Proposition 65
675 Sermorelin acetate ---------- developmental Proposition 65
676 Shale-oils 68308-34-9 cancer Proposition 65
Silica, crystalline (airborne particles of respirable
677 ---------- cancer Proposition 65
size)
678 Sodium dimethyldithiocarbamate 128-04-1 developmental Proposition 65
679 Sodium fluoroacetate 62-74-8 male reproductive Proposition 65

- 25 -
 Soots, tars, and mineral oils (untreated and mildly
680 ---------- cancer Proposition 65
treated oils and used engine oils)
Special-purpose fibres such as E-glass and '475'
681 ---------- cancer IARC
glass fibres
682 Spirodiclofen 14877-71-8 cancer EPA
683 Spironolactone 52-01-7 cancer Proposition 65
684 Stanozolol 10418-03-8 cancer Proposition 65
685 Sterigmatocystin 10048-13-2 cancer Proposition 65
686 Streptomycin sulfate 3810-74-0 developmental Proposition 65
cancer
developmental
687 Streptozocin (streptozotocin) 18883-66-4 Proposition 65
female reproductive
male reproductive
688 Strong inorganic acid mists containing sulfuric acid ---------- cancer Proposition 65
689 Styrene 100-42-5 cancer IARC
690 Styrene oxide 96-09-3 cancer Proposition 65
691 Sulfallate 95-06-7 cancer Proposition 65
cancer
692 Sulfasalazine (salicylazosulfapyridine) 599-79-1 Proposition 65
male reproductive
693 Sulfosulfuron 141776-32-1 cancer EPA
developmental
694 Sulindac 38194-50-2 Proposition 65
female reproductive
695 Talc containing asbestiform fibers ---------- cancer Proposition 65
696 Tamoxifen and its salts 10540-29-1 cancer Proposition 65
697 Tamoxifen citrate 54965-24-1 developmental Proposition 65
698 Temazepam 846-50-4 developmental Proposition 65
developmental Proposition 65
699 Teniposide 29767-20-2
cancer IARC
700 Terbacil 5902-51-2 developmental Proposition 65
701 Terrazole 2593-15-9 cancer Proposition 65
702 Testosterone and its esters 58-22-0 cancer Proposition 65
703 Testosterone cypionate 58-20-8 developmental Proposition 65
704 Testosterone enanthate 315-37-7 developmental Proposition 65
cancer
705 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) 1746-01-6 Proposition 65
developmental
- 26 -
706 1,1,2,2-Tetrachloroethane 79-34-5 cancer Proposition 65
707 Tetrachloroethylene (Perchloroethylene) 127-18-4 cancer Proposition 65
708 p-a,a,a-Tetrachlorotoluene 5216-25-1 cancer Proposition 65
709 Tetrachlorvinphos 961-11-5 cancer EPA
710 Tetraconazole 112281-77-3 cancer EPA
711 Tetracycline (internal use) 60-54-8 developmental Proposition 65
712 Tetracyclines (internal use) ---------- developmental Proposition 65
713 Tetracycline hydrochloride (internal use) 64-75-5 developmental Proposition 65
714 Tetrafluoroethylene 116-14-3 cancer Proposition 65
715 Tetranitromethane 509-14-8 cancer Proposition 65
716 Thalidomide 50-35-1 developmental Proposition 65
717 Thiabendazole 148-79-8 cancer EPA
718 Thialcorprid 111988-49-9 cancer EPA
719 Thioacetamide 62-55-5 cancer Proposition 65
720 4,4'-Thiodianiline 139-65-1 cancer Proposition 65
721 Thiodicarb 59669-26-0 cancer Proposition 65
722 Thioguanine 154-42-7 developmental Proposition 65
female reproductive
Proposition 65
723 Thiophanate methyl 23564-05-8 male reproductive
cancer EPA
724 Thiouracil 141-90-2 cancer Proposition 65
725 Thiourea 62-56-6 cancer Proposition 65
726 Thorium dioxide 1314-20-1 cancer Proposition 65
13463-67-7
727 Titanium dioxide 1317-70-0 cancer IARC
1317-80-2
728 Tobacco, oral use of smokeless products ---------- cancer Proposition 65
729 Tobacco smoke ---------- cancer Proposition 65
developmental
730 Tobacco smoke (primary) ---------- female reproductive Proposition 65
male reproductive
731 Tobramycin sulfate 49842-07-1 developmental Proposition 65
732 Toluene 108-88-3 developmental Proposition 65
733 Toluene diisocyanate 26471-62-5 cancer Proposition 65

- 27 -
734 o-Toluidine 95-53-4 cancer Proposition 65
735 o-Toluidine hydrochloride 636-21-5 cancer Proposition 65
736 Toxaphene (Polychlorinated camphenes) 8001-35-2 cancer Proposition 65
737 Toxins derived from Fusarium moniliforme ---------- cancer IARC
738 Tolyfluanid 731-27-1 cancer EPA
739 Treosulfan 299-75-2 cancer Proposition 65
developmental
740 Triadimefon 43121-43-3 female reproductive Proposition 65
male reproductive
741 Triazolam 28911-01-5 developmental Proposition 65
742 Tribufos 78-48-8 cancer EPA
743 Tributyltin methacrylate 2155-70-6 developmental Proposition 65
744 Trichlorfon 52-68-6 cancer EPA
745 Trichlormethine (Trimustine hydrochloride) 817-09-4 cancer Proposition 65
746 Trichloroethylene 79-01-6 cancer Proposition 65
747 2,4,6-Trichlorophenol 88-06-2 cancer Proposition 65
748 1,2,3-Trichloropropane 96-18-4 cancer Proposition 65
749 Trientine hydrochloride 38260-01-4 developmental Proposition 65
750 Triforine 26644-46-2 developmental Proposition 65
751 Trilostane 13647-35-3 developmental Proposition 65
752 Trimethadione 127-48-0 developmental Proposition 65
753 2,4,5-Trimethylaniline and its strong acid salts 137-17-7 cancer Proposition 65
754 Trimethyl phosphate 512-56-1 cancer Proposition 65
755 Trimetrexate glucuronate 82952-64-5 developmental Proposition 65
756 2,4,6 -Trinitritoluene (TNT) 118-96-7 cancer Proposition 65
cancer
757 Triphenyltin hydroxide 76-87-9 Proposition 65
developmental
758 Tris(1-aziridinyl)phosphine sulfide (Thiotepa) 52-24-4 cancer Proposition 65
759 Tris(2-chloroethyl) phosphate 115-96-8 cancer Proposition 65
760 Tris(2,3-dibromopropyl)phosphate 126-72-7 cancer Proposition 65
761 Trp-P-1 (Tryptophan-P-1) 62450-06-0 cancer Proposition 65
762 Trp-P-2 (Tryptophan-P-2) 62450-07-1 cancer Proposition 65
763 Trypan blue (commercial grade) 72-57-1 cancer Proposition 65
764 Unleaded gasoline (wholly vaporized) ---------- cancer Proposition 65

- 28 -
 cancer
developmental
765 Uracil mustard 66-75-1 Proposition 65
female reproductive
male reproductive
cancer
766 Urethane (Ethyl carbamate) 51-79-6 Proposition 65
developmental
767 Urofollitropin 97048-13-0 developmental Proposition 65
768 Valproate (Valproic acid) 99-66-1 developmental Proposition 65
769 Vanadium pentoxide (orthorhombic crystalline form) 1314-62-1 cancer Proposition 65
770 Vinblastine sulfate 143-67-9 developmental Proposition 65
cancer
771 Vinclozolin 50471-44-8 Proposition 65
developmental
772 Vincristine sulfate 2068-78-2 developmental Proposition 65
773 Vinyl acetate 108-05-4 cancer IARC
IARC
774 Vinyl bromide 593-60-2 cancer
Proposition 65
775 Vinyl chloride 75-01-4 cancer Proposition 65
776 4-Vinylcyclohexene 100-40-3 cancer Proposition 65
4-Vinyl-1-cyclohexene diepoxide (Vinyl
777 106-87-6 cancer Proposition 65
cyclohexenedioxide)
IARC
778 Vinyl fluoride 75-02-5 cancer
Proposition 65
779 Vinyl trichloride (1,1,2-Trichloroethane) 79-00-5 cancer Proposition 65
780 Warfarin 81-81-2 developmental Proposition 65
781 Welding fumes ---------- cancer IARC
782 Wood dust ---------- cancer IARC
783 2,6-Xylidine (2,6-Dimethylaniline) 87-62-7 cancer Proposition 65
784 Zalcitabine (ddC) 7481-89-2 cancer IARC
cancer
785 Zileuton 111406-87-2 developmental Proposition 65
female reproductive

- 29 -
Note: The California Safe Cosmetics Act of 2005 lists the following authoritative bodies, all of which were used as sources of information in creating this list:

• Proposition 65 List of Chemicals Known to Cause Cancer or Reproductive Toxicity – California Office of Environmental Health Hazard Assessment (OEHHA)

• U.S. Environmental Protection Agency (U.S. EPA)

• National Toxicology Program (NTP), including the Center for the Evaluation of Risks to Human Reproduction (CERHR)

• International Agency for Research on Cancer (IARC)

This list is current as of 8/1/09; review of the sources listed above was last conducted on 8/1/09.

California Safe Cosmetics Program:

(877) 325-3223
cosmetic@cdph.ca.gov

- 30 -