DRUG ANALYSIS Nursing

Drug Action Dosage Indications Contraindication Adverse Effects

Responsibilities

Analgesics (Non- 4 ml every 4

Opioid) & hours with
Paracetamol Antipyretics Temp greater Symptomatic · Contraindicated in · Use liquid form for
Nausea, allergic
than or equal relief of pain and patients children and
fever. hypersensitive to drug. reactions, skin patients who have
Paracetamol to 37.5 C · Use cautiously in rashes, acute renal difficulty
exhibits analgesic patients with long tubular necrosis. swallowing.
action by peripheral term alcohol use Potentially · In children, don’t
blockage of pain because therapeutic Fatal: Very rare, exceed five doses
doses cause in 24 hours.
impulse generation. blood dyscrasias
hepatotoxicity in these · Advise patient that
It produces patients. (e.g. drug is only for
antipyresis by thrombocytopenia, short term use and
inhibiting the leucopenia, to consult the
hypothalamic heat- neutropenia, physician if giving to
regulating centre. agranulocytosis); children for
longer than 5 days
Its weak anti- liver damage. or adults for
inflammatory longer than 10 days.
activity is related to · Advise patient or
inhibition of caregiver that
prostaglandin many over the
synthesis in the counter products
contain
CNS. acetaminophen; be
aware
of this when
calculating total
daily
dose.
· Warn patient that
high doses or
unsupervised long
term use can
cause liver damage.
Analgesics (Non- ¾ supp every -Assess for allergic
Symptomatic relief Nephropathy. Hematological
Opioid) & 4 hours for reactions
Opigesic of fever associated reactions, rashes &
Antipyretics Temperature
w/ common other allergic -Assess patient’s
greater than
Paracetamol exhibits childhood infections. reactions. anus after
or equal to
analgesic action by Relief of minor pains administering the
39C
peripheral blockage of eg headache, tootha drug
pain impulse che & earache.
generation. It -Monitor urinalysis if
produces antipyresis any signs of
by inhibiting the Nephropathy
hypothalamic heat-