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Statement of Purpose
I would like to apply to the Master’s Program in Bioinformatics in the University of
Memphis. My career vision is to be a researcher in biotechnology industry. In graduate school, I
would like to work on problems around gene expression and its regulation analysis.
My interest in Bioinformatics started with my undergraduate thesis. Title of the thesis was
"Finding motif in biological sequences using unique binary encoding scheme". This problem is also
known as "Planted motif finding problem (l, d)" where l is the motif-length, d is the maximum
number of mutation, and L is the length of the full sequence to search. The objective was to design
a computationally efficient but simple algorithm. As a result, we designed an algorithm employing
some unique techniques such as Unique Binary Encoding scheme, very fast comparison and
mismatch calculation by exploiting bit-level operations and using simple data structures like array
and linked-list. Complexity analysis of the resulted algorithm's shows it is O(4d) whereas
complexity of exact algorithm proposed by Buhler and Tompa is O(4l). Due to close submission
deadline, we could not do exhaustive performance benchmarking. Rather, we tested with some
sample L=600 datasets where this algorithm shown expected performance. However, my interest
for research in Bioinformatics started along this thesis.
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Khaled Monsoor :: Statement of purpose :: Master’s in Bioinformatics Program
I found the Bioinformatics master’s program and its contents fit in my profile. I would like
to work in Bioinformatics research group under supervision of Dr. Vinhthuy Phan, as I found my
research interest has significant overlap with his. In his continuing research in field of gene
expression and regulation analysis problems, I am eager to synthesize data mining and artificial
intelligence techniques. That will enable high performance solutions for those problems.
Moreover, I am very interested to work in multi-disciplinary teams. I learnt that Memphis has
a large medical center, which may be a live source of multi-disciplinary research collaborations. I
believe that if I can be a part of the Bioinformatics program, I will achieve my best as well as
enrich my research group. Furthermore, I believe that cultural diversity of University of Memphis
with its almost 70 percent international students creates a great learning scenario.
With all of my personal abilities and great zeal for research, I strongly believe that I will
be able to make fundamental contribution in the field of Bioinformatics. I hope best that the MS
Program in Bioinformatics will provide me a great foundation. Therefore, I am looking forward to
hear positive from you.
Best regards,
______________
Khaled Monsoor
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