PATHOPHYSIOLOGY

Precipitating Factors:
Hypertension Predisposing Factors:
Hyperlipidemia Life style (sedentary)
VASOCONSTRICTION
Diabetes Mellitus Vices (Alcohol, smoke)
Heart Diseases Age
Atherosclerosis Diet
Arteriosclerosis Sex
Thrombosis Heredity
Severe dehydration Blockage of the blood Self-medication
vessel
Embolism

Lack of oxygen & High blood pressure, smoking, heart

nutrients supply Ischemic diseases, diabetes, narrowing of arteries
Stroke supplying the brain, high cholesterol and
an unhealthy lifestyle.

Cerebral Ischemia
Hypoxia
Subarachnoid High blood pressure, smoking, and a
Hemorrhage family history of burst aneurysms.

- Cell death Altered cerebral

- Decreased metabolism Severe dehydration, severe infection in
Oxygen level the sinuses of the head and medical or
Venous Stroke genetic conditions that increase a person’s
tendency to form blood clots.

Intracerebral Decreased cerebral

hemorrhage perfusion
Large Artery Hypertension, diabetes, smoking and high
Strokes cholesterol levels.

P Local
Acidosis
A
Transient
R Ischemic Same with Ischemic stroke
A Cytotoxic Attack
L Edema
Y Small Artery Hypertension, diabetes and
S Stroke smoking.
Aneurysm
I Rupture
S Irregular heart beat (atrial fibrillation), a
Embolic heart attack (myocardial infarction), heart
strokes failure or a small hole in the heart called a
PFO (Patent Foramen Ovale).

Brain tissue
Necrosis

D EAT H Severe Cases