NAME_________________________________________

(PRINT YOUR NAME)

EBME 306- Introduction to Biomaterials Quiz #10 - 10

POINTS
DIRECTIONS: Choose the BEST answer that follows each question or statement. (1 point each).
Clearly print your answer in the blank space at the left.

_____A____1. Another name or term for a molecule that binds to an antibody is an:

A. antigen
B. enzyme
C. immunogen
D. immunoglobulin

_____A____2. Which of the following is only associated with the Classical, but not Alternative
Pathway of complement activation?

A. antigen-antibody mediated activation

B. biomaterial mediated activation
C. formation of terminal complex (MAC)
D. release of C3a and C5a

_____C____3. Proliferation of fibroblasts around biomaterials to cause fibrous encapsulation is

mediated by which group of molecules?

A. arachdonic acid pathway molecules

B. complement factors
C. growth factor family of molecules
D. major histocompatibility molecules

_____C____4. Which of the following complement factors dampen or help inhibit complement
activation on biomaterial surfaces?

A. Factors A and B
B. Factors B and D
C. Factors H and I
D. Factors V and VII

_____D____5. A transplant of a pig valve to a human is a/an:

A. allograft
B. autograft
C. isograft

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 D. xenograft

* * * NOTE CHANGE in QUESTION TYPE * * *

6-10. The structure of a typical antibody molecule (IgG) is depicted below. Fill in the blank with the
appropriate response with a word, words or phrase. A hint is given. (1 point each)

B
A

C E

6. At A: ______binds antigen_____________________(one biologic function of this binding region)

7. At B: ______light chain or kappa, lambda________(specific name of this chain type)

8. At C: ______disulfide or S-S____________________(name of this chemical bond)

9. At D: ______carbohydrates_____________________(molecules often associated with this chain type)

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10. At E: _______complement activation, binds to cells ___(one biologic function of this binding region)