Virus Type Infections Caused Site of infection Characteristics Drugs

Localized Naked
Rhinoviruses Colds, sore throat, runny Replicates @ 33°C; Sore throat caused by
nose Confined to upper release of bradykinins
respiratory tract that stimulate nerve
endings. Lytic virus
with tissue destruction
Coronaviruses Colds, sore throat, runny Replicates @ 33°C; Sore throat caused by No antiviral
nose Confined to upper release of bradykinins drugs/preventive
respiratory tract that stimulate nerve measures available
endings.
Localized Enveloped
Parainfluenza virus Bronchiolitis, croup Replicates @37°C; Killed by Cytotoxic T
Lower respiratory tract cells
Influenza virus Colds, pneumonia Replicates @37°C; Lytic with tissue Prevention – vaccine,
Lower respiratory tract destruction Amantadine/Rimantadine
Respiratory Syncytial Colds, pneumonia Replicates @37°C; Forms syncytia Aerosol ribavirin and
Virus Lower respiratory tract (multinucleated hyperimmune globulins
epithelial giant cells);
causes inflammatory
reaction
 Virus Type Infections Caused Site of infection Characteristics Drugs
Systemic Naked
Adenovirus Ex. Sore throat, Respiratory tract, GI 3 live attenuated
pneumonia, pharyngo- tract, Eyes vaccines for military
conjunctivitis
Coxsackie A Sore throat, GI, Respiratory tract, GI, Can move from Resp. none
(enteroviruses) meningitis meninges, muscle tract to GI via
swallowing; cause of
Herpangina(vesicles in
oral mucosa); Moves via
blood stream; Lytic with
tissue destruction
Systemic Enveloped
Epstein-Barr virus Infectious Throat, Lymphocytes Splenomegaly, is a none
mononucleosis, sore herpes virus; confirmed
throat (initial infection) with Monospot Test or
EBV Titer
Herpes Simplex Virus Cold-sores/blister-like Oral or urogenital Remains latent in neural acyclovir
lesions, sore throat ganglia between
(initial infection) episodes