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  • Photodynamic Therapy: BY Prashant Gianani Yogesh Athale

    Загружено:

    Yogesh Athale
    30 просмотров8 страниц
    Photodynamic therapy is a non-thermal technique that uses a photosensitizing agent, light source, and oxygen to destroy cancer cells. It involves injecting a photosensitizing agent that is absorbed by cancer cells, then exposing the tumor to light which activates the photosensitizer and oxygen molecules to destroy the cancer cells. PDT can accurately target affected areas, allow repetition, and has few side effects. However, it is less effective on large, deep tumors. Interstitial PDT and nanoparticle self-lighting PDT were developed to treat thicker tumors by inserting light fibers or using nanoparticles activated by radiation instead of external light. Side effects depend on the treatment area, photosensitizing drug, and

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    Оригинальное название

    Photo Dynamic Therapy

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    © Attribution Non-Commercial (BY-NC)

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    Photodynamic therapy is a non-thermal technique that uses a photosensitizing agent, light source, and oxygen to destroy cancer cells. It involves injecting a photosensitizing agent that is absorbed by cancer cells, then exposing the tumor to light which activates the photosensitizer and oxygen molecules to destroy the cancer cells. PDT can accurately target affected areas, allow repetition, and has few side effects. However, it is less effective on large, deep tumors. Interstitial PDT and nanoparticle self-lighting PDT were developed to treat thicker tumors by inserting light fibers or using nanoparticles activated by radiation instead of external light. Side effects depend on the treatment area, photosensitizing drug, and

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    Attribution Non-Commercial (BY-NC)
    Скачайте в формате PPT, PDF, TXT или читайте онлайн в Scribd
    Отметить как неприемлемый контент
    30 просмотров8 страниц

    Photodynamic Therapy: BY Prashant Gianani Yogesh Athale

    Загружено:

    Yogesh Athale
    Photodynamic therapy is a non-thermal technique that uses a photosensitizing agent, light source, and oxygen to destroy cancer cells. It involves injecting a photosensitizing agent that is absorbed by cancer cells, then exposing the tumor to light which activates the photosensitizer and oxygen molecules to destroy the cancer cells. PDT can accurately target affected areas, allow repetition, and has few side effects. However, it is less effective on large, deep tumors. Interstitial PDT and nanoparticle self-lighting PDT were developed to treat thicker tumors by inserting light fibers or using nanoparticles activated by radiation instead of external light. Side effects depend on the treatment area, photosensitizing drug, and

    Авторское право:

    Attribution Non-Commercial (BY-NC)
    Скачайте в формате PPT, PDF, TXT или читайте онлайн в Scribd
    Отметить как неприемлемый контент
    из 8

    PHOTODYNAMIC THERAPY

    BY PRASHANT GIANANI YOGESH ATHALE

    INTRODUCTION
    PDT is a non thermal technique for local treatment of tumours. Used for both benign and malignant tumours. COMPONENTS Photosensitizer Light source Tissue Oxygen

    MECHANISM OF PDT
    Injection of photosensitizing agent. Absorption by Cancer cells. Exposure of tumour to light. Excitation of Oxygen molecules. Destruction of Cancer cells.

    ADVANTAGES OF PDT
    Used for past 30 years and is a treatment that works. Takes very little time. Does not affect healthy cells. Affected area can be accurately targeted. Repetition possible. No long term side effects. Less expensive as compared to other treatments.

    DRAWBACKS OF PDT
    Light used to activate most photosensitizers cannot pass through more than one centimeter of tissue. Less effective in treatment of large and deep tumours. To eliminate these drawbacks two other techniques are used Interstitial Photodynamic Therapy Nanoparticle Self-lighting Photodynamic Therapy

    INTERSTITIAL PHOTODYNAMIC THERAPY


    Thin optical fibres are inserted into the tumour mass. Used to provide the therapeutic light to the tumour mass. Allows treatment of solid, thicker and deeper lying tumours. Treatment depends on composition of tumour.

    NANOPARTICLE SELFLIGHTING PHOTODYNAMIC THERAPY


    Nanoparticle photosensitizer conjugates are targeted to tumours. Stimulated by X ray or other radiation sources No external light is necessary.

    POSSIBLE SIDE EFFECTS OF PDT


    The side effects that it may cause vary, according to: The area of the body affected by the cancer The type of photosensitizing drug given The time between drug administration and applying the light The amount of skin sensitivity to light following treatment

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