L i D C O

CONTINUOUS, REAL-TIME CARDIOVASCULAR MONITORING

Normal Hemodynamic Parameters

Equation
Systolic (SBP) Diastolic (DBP) SBP + (2 x DBP)/3 (SPmax-SPmin)

Normal Hemodynamic Parameters - Adult

Parameter
Arterial Blood Pressure (BP) Mean Arterial Pressure (MAP) Systolic Pressure Variation (SPV)

Normal Range
90 - 140 mmHg 60 - 90 mmHg 70 - 105 mmHg <5 mmHg unlikely to be preload responsive >5mmHg likely to be preload responsive <10% unlikely to be preload responsive >13-15% likely to be preload responsive <10% unlikely to be preload responsive >13-15% likely to be preload responsive 2 - 6 mmHg

Pulse Pressure Variation (PPV)

(PPmax-PPmin)/[(PPmax + PPmin)/2] x100

Stroke Volume Variation (SVV)

(SVmax-SVmin)/[(SVmax + SVmin)/2] x100

= averaged over 10 sec. of BP data updated every 4 beats

Right Atrial Pressure (RAP) Right Ventricular Pressure (RVP) Pulmonary Artery Pressure (PAP) Mean Pulmonary Artery Pressure (MPAP) Pulmonary Artery Wedge Pressure (PAWP) Left Atrial Pressure (LAP) Cardiac Output (CO) Cardiac Index (CI) Stroke Volume (SV) Stroke Volume Index (SVI) Systemic Vascular Resistance (SVR) Systemic Vascular Resistance Index (SVRI) Pulmonary Vascular Resistance (PVR) Pulmonary Vascular Resistance Index (PVRI) Systolic (RVSP) Diastolic (RVDP) Systolic (PASP) Diastolic (PADP) [PASP + (2 x PADP)]/3

15 - 25 mmHg 0 - 8 mmHg 15 - 25 mmHg 8 - 15 mmHg 10 - 20 mmHg 6 - 12 mmHg 6 - 12 mmHg 4.0 - 8.0 l/min 2.5 - 4.0 l/min/m2 60 - 100 ml/beat 33 - 47 ml/m2/beat 800 - 1200 dynes sec/cm5 1970 - 2390 dynes sec/cm5/m2 <250 dynes sec/cm5 255 - 285 dynes sec/cm5/m2

HR x SV/1000 CO/BSA CO/HR x 1000 CI/HR x 1000 80 80 80 80 x x x x (MAP - RAP)/CO MAP - RAP)/CI (MPAP - PAWP)/CO (MPAP - PAWP)/CI

Hemodynamic Parameters - Adult

Parameter
Left Ventricular Stroke Work (LVSW) Left Ventricular Stroke Work Index (LVSWI) Right Ventricular Stroke Work (RVSW) Right Ventricular Stroke Work Index (RVSWI) Coronary Artery Perfusion Pressure (CPP) Right Ventricular End-Diastolic Volume (RVEDV) Right Ventricular End-Systolic Volume (RVESV) Right Ventricular Ejection Fraction (RVEF)

Equation
SV x (MAP - PAWP) x 0.0136 SVI x (MAP - PAWP) x 0.0136 SV x (MPAP - RAP) x 0.0136 SVI x (MPAP - RAP) x 0.0136 Diastolic BP - PAWP SV/EF EDV - SV SV/EDV

Normal Range
58 - 104 gm-m/beat 50 - 62 gm-m/m2/beat 8 - 16 gm-m/beat 5 - 10 gm-m/m2/beat 60 - 80 mmHg 100 - 160 ml 50 - 100 ml 40 - 60%

Oxygenation Parameters - Adult

Parameter
Partial Pressure of Arterial Oxygen (PaO2) Partial Pressure of Arterial CO2 (PaCO2) Bicarbonate (HCO3) pH Arterial Oxygen Saturation (SaO2) Mixed Venous Saturation (SvO2) Arterial Oxygen Content (CaO2) Venous Oxygen Content (CvO2) A-V Oxygen Content Difference (C(a-v)O2) Oxygen Delivery (DO2) Oxygen Delivery Index (DO2I) Oxygen Consumption (VO2) Oxygen Consumption Index (VO2I) Oxygen Extraction Ration (O2ER) Oxygen Extraction Index (O2EI) (0.0138 x Hgb x SaO2) + (0.0031 x PaO2) (0.0138 x Hgb x SvO2) + (0.0031 x PvO2) CaO2 - CvO2 CaO2 x CO x 10 CaO2 x CI x 10 (C(a - v)O2) x CO x 10 (C(a - v)O2 x CI x 10 [(CaO2 - CvO2)/CaO2] x 100 [SaO2 - SvO2)/SaO2 x 100

Equation

Normal Range
80 - 100 mmHg 35 - 45 mmHg 22 - 28 mEg/1 7.38 - 7.42 95 - 100% 60 - 80% 17 - 20 ml/dl 12 - 15 ml/dl 4 - 6 ml/dl 950-1150 ml/min 500 - 600 ml/min/m2 200 -250 ml/min 120 - 160 ml/min/m2 22 - 30% 20 - 25%

02/03BM1462

LiDCO Ltd, as the manufacturer and supplier of PulseCO and LiDCOplus medical devices, does not practice medicine and does not recommend these normal parameter metrics for use on a specific patient. The medical practitioner who performs any procedure is responsible for determining and utilizing the appropriate techniques, devices and treatments for each individual patient. LiDCO Ltd is not responsible for selection of the appropriate device or treatment to be utilized on an individual patient.