BackgroundandHistoryofLaminine

WHATISLAMININE?
Laminineisanaminoacidpeptidewhichhasalltherequirednourishmenttosustainlife.(Anaminoacidisthe buildingblockofproteininwhicheachislinkedtogetherthroughpeptidebonds;andapeptideisanamino acidcompoundthatconsistsof2ormoreaminoacids). Thereareover100aminoacidsthatoccurnaturally,butonlytwentyofthemareinvolvedinmakingupa protein,andareclassifiedaseithernonessentialoressential.Nonessentialaminoacidsaresonamed becausetheycanbesynthesizedinthebody.Theseincludealanine,arginine,asparticacid,asparagine, cysteine,glutamicacid,glutamine,glycine,proline,serine,andtyrosine.Essentialorindispensableaminoacids cannotbesynthesizedinthebodyandcanonlybeobtainedthroughfood.Thesebecometheratelimiting factorsforthesynthesisofcertainproteinsinthebody.Theessentialaminoacidsarehistidine,isoleucine, leucine,lysine,methionine,phenylalanine,threonine,tryptophan,andvaline. BeforetheproductionofthesupplementknownasLaminine,noothercompanieshaddevelopedand marketedacombinationofaminoacids,peptides,andgrowthfactorsrequiredtosustainrobusthealth. THEHISTORYOFLAMININE: In1929aCanadiandoctor,Dr.JohnRalstonDavison,theorizedthataninjectedextractfromfertilizedheneggs couldbehelpfulforanumberofhiscancerpatients.Davidsonspentwelloveradecadedevelopingand researchinghistheory.HepublishedanumberofstudiesonhisdiscoveryintheCanadianJournalof Medicine,however,whenDr.Davidsonpassedawayin1943,hisresearchonfertilizedheneggsquicklyand quietlycametoahaltandwaslost. Itwasntuntilalmost50yearslaterthatthepursuitoffertilizedheneggextractwas revivedbyNorwaysforemostexpertoneggresearch, Dr.BjodneEskeland.

Dr.Eskelandalsohypothesizedthatincubated,fertilizedheneggscontainedaspecialcombinationofamino acids,peptides,andproteinfractionsthatcouldhelpprovideanincrediblearrayofhealthbenefitswhen consumedbyhumans. Intheory,thesepartiallyincubated,fertilizedeggsspecifically9dayoldfertilizedeggscontainallthe nutrientsrequiredtostartanewlife.Thisincludesvitamins,mineralsandproteins,aswellasimportant defensefactors,growthfactors,hormonesandotherbiologicallyactivecomponents.Whilenotmuchwas knownaboutthegrowthfactoratthetime,thehighlevelofoligopeptides(smallpeptides)foundinLaminine allowsforrapidtransportacrossthemembranesofthegastrointestinaltractinordertoprovideeffective benefitsfromtheseaminoacids. ManufacturerofLaminine: Lamininesparentcompany,LifePharmInc.,researchedwhatwasbeingdonewiththiskeyingredient,also calledYTEorYoungTissueExtract,thathaddemonstratedsomanyhealthassociatedbenefits. LifePharmcontactedtheteamofscientistsinNorwayworkingwithYTE,andnowhaveexclusiverightsfor distributionofthisproductunderthebrandname"Laminine"andhaveitmanufacturedexclusivelyforthem. Apatentedprocessextractsthecriticalnutritionalfluidfromthewhiteofaneggattheprotoembryonicstage (onlytheeggyolkispresentandnodevelopingchicken),sothemanufacturercalleditProtoEmbryonicStage Extract(PESE).Theextractnotonlyprovidesamechanismofrapidtransportofverycriticalnutrients,butalso

containsBasicFibroblastGrowthFactor,whichisprobablyresponsiblefortheaminoacidsandpeptidesbeing utilizedintherightmanner,bydirectingtheirusebythebody.Thisgrowthfactorisalsoresponsiblefor nurturingthebodysownstemcellsbothdifferentiated,andundifferentiated(undifferentiatedstemcellscan rebuildanyofthetissuesofthebody).Commonaminoacidformulationsdonotcontainthisgrowthfactor, andmaynotbeutilizedbythebraininthemostefficientmanner. AteamofscientistsleadbyDr.AlexMartin,aleadingdoctorinthestudyofnutritionalsupplements,atthe LifePharminstituteoftechnologywenttoworktodevelopwhattheytermed"theperfectsupplement".Using PESEasabaseingredient,theylookedatthesymptomscauseddeficienciesinmostbyourdiets,andthe toxinsinourenvironment,andthenevaluatedmethodstosuperchargethePESEformoderndayuse.Skin andhair,health,moods(depression),memoryloss,fatigueandcardiovascularhealtharemostcommonly affectedbytodayslifestyle.ThesesymptomsandhowLaminineaddressesthemarecoveredlaterinthis booklet. Havingaperfectlybalanced,natural,transportmechanismwithPESELifePharmknewthattheaddedamino acidswillnotonlyfindtheirwaytotherightareasofthebody,butwouldbeguidedproperlytoperformtheir functionefficiently.Themanufacturerthenaddedtheaminoacidsmostcriticalforthehealthofyourskin, hair,memoryfunction,cardiovascularhealthandrestorationofenergy,fromnaturalplantproteinandmarine protein.Theseproteiningredientsfromland("phytoproteins"orplantproteinsfromtheyellowpea),sea (marineproteinsourcesfromsharkcartilage)combinetoformandenhancethepowerfulsymbiotic relationshipofthebaseingredientinLamininethatiscalledOPT9.

SPORTSNUTRITION OPT9andcreatinereinforceeachother(thereisnoaddedcreatineintheLaminineproduct).Thenetresultof usingthiscombinationisimprovedperformance,decreasedfatigue,andareducedriskofenergydepletionin themuscles. In1996,adoubleblindtrialontheuseofPESEconductedattheUniversityofColoradoshowedthatthegroup usingitexperiencedastrengthincreasethatwasnearlydoublethatofthegroupusingcreatinealone.PESE andcreatinetogetherwerefoundtooutperformcreatineandotherfoodsupplementsintheareasof endurance,training,motivation,andsubjectivehealthandwellbeing,andithastheenthusiasticendorsement ofmanytopathletes.Theyreportrecoveringfasteraftertraining.Thisislinkedtoasubstantialreductionin lacticacidproduction,whichalsocontributestoincreasedstamina.

 ButwhatdoescreatinehavetodowithOPT9?Itappearsthatcreatineandtheeggproteinfractionsthatare foundinOPT9reinforceeachother,resultinginaprominentincreaseineffectiveness.Thismeansthat bodybuildersandathletesexperiencegreatlyenhancedbenefitswhenaddingLamininetotheirregimen.No wondertheproducthastheenthusiasticendorsementofsomanyprofessionalathletesandbodybuilders. Whetheritisaphysicalormentalchallengeyoufaceorjusttheneedtohandleeverydaydemands,Laminine mayhelp. Benefitsmayinclude: 1.Adelayinlacticacidproduction 2.Theabilitytotoleratelongertrainingsessions. 3.ImprovedStamina 4.MaximumMuscularStrength 5.FasterRecoveryaftertrainingsessions 6.Quickerrecoveryfromphysicalexertion 7.Bettermuscletone 8.Increasedmusclestrength MEMORYENHANCEMENT ThemostpronouncedeffectofartificialsweetenersandMSGinthebodyistointerferewiththissynergistic performance.ThemanufacturerthereforedecidedtoaddressthisissuewhentheyformulatedLaminine. MemoryfunctioniscontrolledbyawellbalancedjointeffectofGlutamateandGlycine.Boththeseamino acidsactsynergisticallytogethertoplayacriticalroleintheabilityoftwoneuronstoconnect,animportant cellularmechanismforlearningandmemorytotakeplace.PESEislowintheseaminoacids.Therefore, LaminineenhancestheselevelsinOPT9bytheadditionofanisolatedvegetableprotein(fromtheyellowpea) toprovideextraglutamicacidandwithmarineproteinextract(frompurifiedsharkcartilage)toprovideextra Glycine.PESEisusedtoprovideadditionalFGFintheaidofmemory.FGFisknowntobuildneurites,the bridgesbetweentheneuronsandwhichactasthereceptorsandtransmittersofsignals.ResearchshowsFGF alsoinhibitsandeliminatesmutantproteingenes,inthiscase,quitepossiblyblockingthegenesresponsible formemoryloss. In1962,itwasdiscoveredthatthatneurologicstemcellsresideincertainpartsofthebrain,oftenwhere damageordysfunctionispresent.ItisalsoscientificallyproventhatFibroblastGrowthFactor(FGF)feedsand nurturesthesestemcellstofacilitatethehealingofthisdamage,dysfunction,andscarredtissue.Lately, compellingargumentshavebeenmadetoinjectFGFdirectlytotreatorcureHuntingtonsdisease, Schizophrenia,OCDandAutism. Thesynergisticeffectofbuildingtheneurites,nurturingthestemcells,havingthemostrelevantaminoacids andfactorstoguidewheretheaminoacidsgo,makesLaminineperformextremelywellinmemory enhancement. AnotherveryeffectivecombinationinLaminineisthecombinationofthetwoingredientsLeucineand Isoleucine.ThiscombinationinincreasedbycombiningthePESEandthevegetableproteinextract.Leucine andIsoleucineprovideingredientsforthemanufacturingofmanyessentialbiochemicalcomponentsinthe body,someofwhichareutilizedtostimulatetheupperbrainandhelpyoutobemorealertandfocused. ItsnowondertherehavebeenreportsofmanypositiveeffectsofLamininewithpeoplesufferingfrom Alzheimerssyndrome,ADD,andageneralincreasedmemoryandmentalfocusinourbusylives.

MOODENHANCEMENTANDDEPRESSION Depressioniscausedbymanyinternalaswellasexternalfactors,includingstress.Inthebrain,theserotonin uptakeandreleasemechanismisaffected.Serotoninisanessentialneurotransmitterwhichhasbeencalled the"happychemical",asitisassociatedwithfeelingsofcontentment,wellbeingandhappiness.Serotonin alsosupportscognitivefunctions,includingmemoryandlearning.TheSSRI(SelectiveSerotoninreUptake Inhibitor)marketisan$18billiondollarperyearmarketprovidingprescriptiondrugswhichhave demonstratedtheabilitytoincreaseserotoninlevelswithinthenervesynapses,therebycausingmood improvementandalleviationofdepression.Butthesebenefitsdonotcomenotwithoutsignificantexpense andsomenotablesideeffects.Conversely,Laminineisanallnaturalproductthatcontainstheaminoacid Lysine;derivedfromPESEandnaturalvegetableproteins.Thecombinationofthesetwocomponentsdelivers ahigherlevelofLysineintheOPT9thaneitheringredientwouldbyitself(thisiscalledsynergism).Lysineis knowntoregulateserotoninlevelsinthebrain. Some20millionpeopleworldwideexperiencedepressionseriousenoughtowarrantbeingplacedon prescriptionmedication(usuallyanSSRI).Many,anestimated16to30percent,whotakesuchdrugs experiencesexualdysfunctionasasideeffect.Somemedicalexpertsbelievethetruenumberofpeople experiencingthissideeffectmaybeashighas78percentduetothefactthattheconditionoftengoes unreportedbypatients.ClinicalstudieshaveshownthatLamininemaybebeneficialinenhancinglibidoamong thosetakingantidepressants. ManypeopletakingLamininereportapronouncedimprovementintheirmoodandanincreasedabilityto managestressonadailybasis.Agreateroverallengagewithothersanddesiretoaccomplishthings. CARDIOVASCULARHEALTHANDLIBIDOENHANCEMENT ThePESEandVegetableproteinsprovideaverypotentdoseofArginine.Arginineisaprecursorofnitricoxide andplaysavitalroleinavarietyofbiologicalprocesses.Theinnerliningofbloodvesselsusesnitricoxideto signalthesurroundingsmoothmuscletorelax,thusresultinginincreasedbloodflow.Effectsinclude modulationofthehaircycle,andincreasedlibido.Nitricoxideisalsoknownforgrowthhormoneformation, increasingdefenseoftheinternalorgansagainsteffectsofaging. REMOVINGTOXINSFROMTHEBODY PESEcontainsCysteine,whichisaprecursortoglutathione,apowerfulantioxidant,receivingmuchattention todayforhealthierlookingskin.Antioxidantsfightfreeradicals,(freeradicalsareharmfulcompoundsinthe bodythatdamagecellmembranesandDNA).Freeradicalsoccurnaturallyinthebody(duringthenormal energyproducingmetabolicprocesseswithinourcells),butenvironmentaltoxins(includingultravioletlight, radiation,cigarettesmoking,andairpollution)canincreasethenumberofthesedamagingparticles.Free radicalsarebelievedtoplayaroleinagingaswellasthedevelopmentofanumberofhealthproblems, includingheartdiseaseandcancer. NAC(NAcetylCysteine)isapowerfulantioxidantandcanhelppreventsideeffectscausedbydrugreactions andtoxicchemicals,andhelpstoalleviateandbreakdownmucusinthebody.NACappearstohavebenefits intreatingsomerespiratoryconditions,suchasbronchitisandCOPD.Thisisverycrucialforthebodyslife functions,asNAChelpsthebodyneutralizetoxins,heavymetals,suchasmercuryfromdentalamalgam fillings,cadmiumandleadfrompaint,andcigarettesmoke.TheSulfhydrylbalancehasalsobeenlinkedto enhanceresistancetoviralinfections.NACisoneofthemosteffectiveoralchelatingagents. Takenregularlyoveraperiodoftime,NACwillremovemanytoxicheavymetalsfromthebody.NAChasbeen showntobeaprotectiveagentinmanydiseasesandconditionsinwhichfreeradicalsplayarole.Thisincludes cancer,AIDS,cirrhosis,aswellaspollutiondamagefromsmokingorotherchemicals.

TheaddedpotentdoseofGlycine,fromanaturalmarineproteinsource,furtherenhancestheantiaging effectofglutathioneinthebody.Glycinefromthemarineproteinalsobuildscollagen,makingtheskinlook healthierandlesswrinkled. SKIN,HAIR,&HEALTH ThemanufacturerhasaddedanadditionalcomponenttoOPT9inLaminine.TheaddedpotentdoseofGlycine, frommarineprotein,furtherenhancestheantiagingeffectofglutathioneinthebody.Glycinefromthe marineproteinalsobuildscollagen,makingtheskinlookhealthierandlesswrinkled. Hairiscomposedfromprotein.LCysteineisanaminoacidthatisknowntopromotehairgrowth. Itimproveshairqualityandtexture,anditisknowntodoublethelengthofhair.LCysteinealsopreventshair fromfallingout,andithasadetoxifyingeffectinthebody.ThePESEandVegetableproteinsalsoprovidea verypotentdoseofArginine.Arginineisaprecursorofnitricoxideandtheseeffectthemodulationofthehair cycle. THELECITHINCONNECTIONANDCONTROLLINGCHOLESTEROL Yearsago,pioneeringnutritionistAdelleDavisrecognizedtheerrorintheassumptionthateatingcholesterol richfoodscausesabuildupofcholesterolinthearteriesandleadstoheartdisease.Shetaughtthatacousin ofthefatfamily,lecithin,playsavitalroleincontrollingbloodcholesterollevels.Lecithin,foundinthehuman body(andconcentratedinthebrain),isafatemulsifierthatbreaksdowncholesterol,preventingitsbuildupin thebody,Lecithinisalsofoundineggs.Whiletheymayprovidecholesterol,theyalsoprovidethelecithin neededtobreakcholesteroldown. FATIGUE&ENERGY LamininecombinesthetwoingredientsLeucineandIsoleucine(knownasbranchedchainaminoacids)from thePESEwithanaddeddosefromthevegetableproteinextract.LeucineandIsoleucineprovideingredients forthemanufacturingofotheressentialbiochemicalcomponentsinthebody,someofwhichareutilizedfor theproductionofenergy,stimulantstotheupperbrainandhelpingyoutobemorealert. Manypeopletodayaremildlyfatigued,andothersareseriouslyenergydeficient.Fatigueisasymptomthat accompaniesmostillnesses,bothacuteandchronic:itisoftenanearlywarningsignthatserioushealth problemsareintheprocessofdeveloping.Persistent,extremefatiguemaybeasignofchronicfatigue syndrome(CFIDS).TheCenterforDiseaseControl(CDC)estimatesthatchronicfatiguesyndromeaffects between100,000and250,000peopleintheUnitedStates,butmanyresearchersbelievethatthedisorderis muchmoreprevalentthanthat.Whatiscertainisthattherearemanytiredpeopleeverywhere strugglingtogetthrougheachday. Whetheryoureaprofessionalathleteoraweekendwarrior,youcouldprobablyusemoreenergy,who wouldntwanttofeelmoreenergetic,inordertobetterfacethechallenges,bothphysicalandmental,inlife. Thosewhoseworkdemandsmentalconcentrationarebeingsappedofenergyjustlikethosewhohave physicallydemandingjobs.Whetherthetaskathandisatennismatchorachesstournament,increased energyandstaminacanleadtoabetteroutcome. STRESSMANAGEMENT&IMPROVEDSLEEP UseofLamininepromotesafeelingofrelaxationeffectthatmaybetosomedegreeattributedtothedramatic decreaseinlevelsofthestresshormonecortisolproducedafterLamininesingestion. Asindicated,Lamininereducesstresshormonelevelsdramaticallyinthebody. Whencortisollevelsdecline,wefeelmorerelaxed.StudiesshowthatvirtuallyeveryonewhousesLaminine

experiencesagreatersenseofrelaxationandwithit,manyextrabenefits,suchasimprovedsleep. Elevatedlevelsofstresshormonesnotonlymakeusfeelonedge,butalsopredisposeustoanumberof stressrelateddiseases,whichincludeseriousconditionssuchashypertension,heartdisease,stroke,asthma, irritablebowelsyndrome,ulcerativecolitis,eczema,andautoimmunedisorders.Bymanagingstresshormone levels,wemaybehelpingtopreventormanagethesedisorders. HOWDOESLAMININEWORK&WHAT'SINIT? WhatdoesOpt9Contain? OPT9containsanaturalcombinationofnutrients,includingaminoacids,glycopeptides,andoligopeptidesthat comefromfertilizedeggs,isolatednaturalplantproteins(yellowpea),andnaturalmarineelements(purified sharkcartilage)thatworktogethertoformasuperfoodornutraceuticalforthesupportofboththemindand thebody. TheHealthBenefitsofLaminine Lamininehasbeenassociatedwithavarietyofpotentialhealthbenefits,including:increasedstrengthand vitality,improvedstaminaandenergy,increasedlibido(inbothmenandwomen),reducedstress,improved sleep,quickerrecoveryafterworkoutandimprovedmuscletone,increasedleanmusclemass,increased alertnessandmentalclarity,reduced"brainfog",improvedmood,improvedcalmnessandhappiness (Lamininehasbeencalled"thehappypill"),andoverallimprovedsenseofwellbeing. Thesevariouseffectsmayallberelatedtothesignificantreductionofthestresshormonecortisol(byabout50 percent)aftertheingestionofLaminine,aswellasincreasesinthehappychemical,serotonin.Additionally, Laminineprovidestheprecursors(buildingblocks)tonutritionallysupporttheproduction,andmaintenanceof laminininthebody.Lamininistheproteinnetworkfoundationformostcellsandorgansinourbodies. Lamininsareanimportantandbiologicallyactivepartofthebasallamina,andinfluencehowthecellsofour bodydifferentiate(stemcells),migrate,holdtogether(adhesion)andsurvive.Lamininhasbeencalledthe "rebarofthehumanbody"muchlikerebar(strongmetalrods)structurallyholdtogetherandstrengthen concreteusedtobuildbuildingsandhighways. WhatexactlyisPESE,andhowmuchisknownaboutitsbenefits? ProtoEmbryonicStageExtract(PESE)isthenamethemanufacturerhasgiventheingredientinLamininethatis derivedfromtheliquidwhitesofpartiallyincubated(9daysold)fertilizedorganicheneggs.Thecholesterol containingyolkisexcluded.PESEcontainsthemostpotentandbalancedcombinationofaminoacids,aswell asotherfactorssuchasFibroblastGrowthFactor(FGF).Aminoacidsderivedfromsuchfluidscombinedwith thegrowthfactorsareabletoenhancebrainfunctionbecausetheyarepreciselyengineeredtosupportthe mostcomplexstageofdevelopmentofalivingcreature,thebeginningoflife.Thisbeginningisthemost criticalstageinourdevelopment,justlikethetakeoffisthemostcomplexfunctioninflyinganairplane,orthe foundation(andstructuralrebar)isinconstruction,andisthemostessentialfunctioninthelifeofabuilding. Thehealthbenefitsofthehenegghavebeenknownforcenturies.Recently,furtherinvestigationofthe mechanismofthedevelopmentofanembryoinaneggduringincubationhasrevealedthescientific equivalentofthemiracleoflife.Thepotencyofthenutrientsavailabletotheembryoatthelatterstageof developmentstagehasalwaysbeenassumedtobehigh,butitwasonlyrecentlythatthechemicalstructureof theoriginaleggsolidsforthesecriticalstageswasobtained.Duringthisstage,oligopeptideswithsmall molecularweightswereidentified.Theseshortchainsofaminoacidsareabletocrossthedigestivebarrier withoutbreakingdownorchangingtheratiosandproportions.Peptidesarefarmorepotentthanother neurotransmitters,requiringonlysmallamountstoproduceaprofoundeffect.Heatcandestroythesecritical proteinfactors,andLaminineshouldnotbeheatedover118degrees.Itshouldbeprotectedfromprolonged exposuretoheat,andshouldneverbemixedintosteaminghotliquids,orbakedintofoods.

 Additionally,theuptakeoftheFibroblastGrowthFactor(FGF)(presentinPESE)bytheembryosharply increasesandtheFGFpresenthavebeenisolatedthroughapatentedprocesspreciselyattherightstageof incubation,extractedandfreezedriedtobringthemiracleoflifebenefitstohumans. ExtractingPESEbeforethepeptidesandFGFareuseduptobuildorgansandbones,allowsustoprovidethis building,repairing,maintenancemechanismofperfectlybalancedaminoacids,peptidesandgrowthfactorsto humans.WhilevirtuallyunknownintheUnitedStatesuntilveryrecently,PESEhasbeenmarketedsuccessfully asanutritionalsupplementinScandinaviaformanyyears. HowisFibroblastGrowthFactor(FGF)helpfultohumans? Thepreciseblendofoligopeptidesmaybeseenasbuildingblocks,butwithoutabridge,oramaster builder/director.TheroleofsuchadirectorisfulfilledbyagrowthfactorknownastheFibroblastGrowth Factor,orFGF.FGFisprolificinPESE,aswellasinthehumanplacenta.Adetaileddaybydaystudywas performedin1988.Discoveredfourdecadesagointheseventies,andalsoexistingasapeptide,thisFGFis criticalinthedevelopmentofembryos,includinghumans.However,itisnotfoundtobecirculatinginthe humanadultbodies.FGFisresponsibleforbuildingtheliningsinthebloodvessels,creatingtheinfrastructure forthenutrientstoflowtocriticalareasofthebrainandorgans.ResearchcreditsFGFwiththepotentialto directlyaffectmanyneurologicdisordersbecauseoftheabilityofFGFtoaffectthegrowthofneurites. Neuritesaresignalsenders(Axons)andsignalreceivers(Dendrites)thatareattachedtothebrainneurons. Researchhasalsoclearlydemonstratedthatnewcellculturesshowadramaticincreaseinpeptideandamino aciduptakeinthepresenceofFGF.Thisresultsupportsthehypothesisthatembryonicgrowthisinfluencedby averyprecisemechanism,whichcombinesuniquecombinationsofaminoacids,peptidesandFGF. SinceFGFisnotcirculatinginadults,multipleresearchprojectsontheeffectsofFGFserumstocureneurologic disordershavebeencarriedout.FundamentaltotheresearchisthefactdiscoveredbyAltmanin1962that neuralSTEMcellsareformedbythebodyinresponsetoabnormalities,andareresidentincertainzonesofthe brainundergoingbiologicstress.Thebrainisthereforereadytorepairthedamage,andthesecellshaveshown todifferentiateintoawiderangeofneurons.Neuronsderivedfromsuchneuralstemcellsarecapableof migratingtovariousregionsoftheCentralNervousSystem. Useofvegetableproteins Vegetableproteinhasanessentialaminoacidprofile,whichisveryclosetothatoftheidealproteinforhuman nutrition(FAO/WHO1985and2002).ForLaminine,apatentedprocessfurtherisolatestheseproteinsinorder toeliminateunnecessarycompoundswhichcanneutralizethebenefitsoftheessentialaminoacids. TheresultisancompoundwhichishighinGlutamicacid,(furtherenhancingthecognitivefunctionofthe brain),branchedchainaminoacids(tocounterinsomnia),Lysine(tocontrolreleaseofserotonin,controlling moods),andArginine(promotingNitricOxideandgrowthhormoneformation).Thesespeciallyisolated proteinscreateasynergisticallypotentcompositiontoenhancebrainactivity. UseofMarineProteins ThehighlevelsofGlycineinthespeciallyextractedmarineprotein(purifiedsharkcartilage)usedinLaminine, combinedwithasignificantamountofhydroxyprolinetostabilizetheglycine,makesitaprimarycandidatefor aterrificbrainfood.Byitself,Glycineisaneurotransmitter,primarilyutilizedbythebraintocontrolglutamate levels.IncombinationwithinOPT9,itbecomesapowerfulforcetoenhancememoryfunctioninthebrain. AMINOACIDSANDTHEIRROLES Aminoacidsarecriticaltolife,andhavemanyfunctionsinmetabolism.Oneparticularlyimportantfunctionis

asthebuildingblocksofproteins,whicharelinear(straight)chainsofaminoacids.Lamininesuniqueblendof ingredientscombinestoproduceacompletechainof20aminoacids.Thefollowingisalistofthoseamino acidsandtheirpotentialbenefits.Aminoacidsareorganiccompoundsthatcombinetoformproteins.When proteinsaredigested,aminoacidsareleft.Thehumanbodyrequiresanumberofaminoacidstogrowand breakdownfoodandisaveryimportantpartofnutrition. AcompletebalanceofaminoarecontainedinLaminineandinclude:

Essential Nonessentialor ConditionallyEssential Alanine Arginine Asparagine Asparticacid Cysteine

Histidine Isoleucine Leucine Lysine Methionine

Phenylalanine Glutamicacid Threonine Tryptophan Valine Glutamine Glycine Ornithine Proline(Hydroxyproline) Selenocysteine Serine Taurine Tyrosine

Glycineandglutamineareprecursorsofnucleotides.Nucleotidesaremoleculesthat,whenjoinedtogether, makeupthestructuralunitsofRNAandDNA.Pleasenote:GlutamicacidandGlutamineareNOT monosodiumglutamate.ThereisnoaddedMSGinLaminine. Thesebuildingblocksofproteinsperformvariousvitalrolesinthebodyandhelpustoremainhealthyinmany ways. Antioxidantshelpingwithcombatingfreeradicalsandenvironmentaltoxinsincludingultravioletlight, radiation,cigarettesmoking,andairpollution. Benefitsintreatingsomerespiratoryconditions,suchasbronchitisandCOPD.Angina,Chronicbronchitisand ChronicObstructivePulmonaryDisease(COPD),Influenza,AcuteRespiratoryDistressSyndrome(ARDS), HIV/AIDS. Reducingsymptomsofasthma,cysticfibrosis,andemphysema. HelpingtoImproveorPreventingcoloncancer.

HelpingtoImproveorPreventingcataractsandmaculardegeneration. HelpingincreaseHDLgoodcholesterol. Helpingincreasefertilitywhentakenalongwithfertilitydrugsinpeoplewithpolycysticovarydisease. Helpingimproveoutcomeinchildrenwithadvancedcerebraladrenoleukodystrophy,atypeofleukemia. Helpingtreatcocaineaddiction,schizophrenia,andgamblingaddictions. Reducinglungcancerriskamongsmokers. DecreaseCelloxidation. Enhancesneurotransmittersinthebrain. Assistintheformationoftoothenamel. Bloodcoagulationregulation. Immuneresponse. Increasedmemoryfunction,cognition,andvoluntarymovementandlearningability. Aidintheeliminationoftoxicammoniaintheformofnitrogenfromthebody. Improvehairandskin. Fightinsomnia. Increaseenergyandendurance. Regulationofbloodpressureunderstress. Controlsreleaseofserotoninandmoodimprovement. Increasedvasodilatationwhichincreasesbloodflow. Humanswithatherosclerosis,diabetesorhypertensionoftenshowimpairedNitricOxidepathways. THEROLEOFPEPTIDES Smallaminoacidchainpeptides(suchasthosecontainedinLaminine),commonlyknownasoligopeptides,are veryeasilytransportedthroughtheintestinal,membrane.Theyaresometimesusedastransportmechanisms fordrugs. Peptidesareshortpolymersformedfromthelinking,inadefinedorder,ofaminoacids.Proteinsaremulti peptidechains.Proteinsmustbebrokendowntosmallerandsmallerpeptides,andeventuallyanaminoacid, toperformitsfunctions.Dietaryintakeofpeptidesandaminoacids,whichcanreachtheirdestination, therefore,canbeextremelybeneficial.Peptidesarethemostabundantcompoundsinthehypothalamusof thebrain,andperformvitalfunctionsofcommunicatingsensoryimpulsestotheendocrinesystem(hormone producingglands). Understandingthemechanismsoftheeffectofpeptides,andthetypesofpeptides,isacomplexfieldandis beingstudiedextensively.Unfortunately,thesestudiesaredoneinisolationanddisregardthewholepictureof themanycomplexmechanismswhichexistinourbody.Further,thesestudiesareusuallyfocusedona particularaminoacid,peptideorotherneurotransmitters.Whiletheresultsidentifythefinalactivitywiththe aminoacid/peptide,themechanismoftransportofsuchcriticalaminoacid/peptidestothefinaldestinationis asubjectofmajorarguments.Theseargumentscastashadowontheimportanceofnutritionalsupplements. Mostdoctorswilltellyouthatnutritionalsupplementscannothurt,butstopshortofendorsingthem. Thereasonisthelackofevidencethattheactiveingredientshavebeenformulatedinthecorrectformthat canbeusedbythebody. Formoreinformation,pleasecall +97155-5887930 or email lami9uae@gmail.com www.laminine.suilt.com.ph Disclaimer:Likeallnutritionalsupplements,thisproductisnotintendedtodiagnose,mitigate,treatorprevent anydisease.