Code No: RR412301 Set No.

1
IV B.Tech I Semester Regular Examinations, November 2007
GENOMICS AND PROTEOMICS
(Bio-Technology)
Time: 3 hours Max Marks: 80
Answer any FIVE Questions
All Questions carry equal marks
⋆⋆⋆⋆⋆

1. Discuss in detail about the Abiotic sythesis of organic monomers. [16]

2. Explain how chromatin structure plays important role in Eukaryotic gene regula-
tion. [16]

3. What do you mean by chaperons and how they are involved in post translational
modification of protiene? [16]

4. Discuss in detail how many microbes genome is sequenced. [16]

5. What do you mean by homology and mention applications of homology? [16]

6. What do you mean by biochipnology. Discuss? [16]

7. Mention different applications of SNPs. [16]

8. How could you explain drug design using known receptor structures? [16]

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Code No: RR412301 Set No. 2
IV B.Tech I Semester Regular Examinations, November 2007
GENOMICS AND PROTEOMICS
(Bio-Technology)
Time: 3 hours Max Marks: 80
Answer any FIVE Questions
All Questions carry equal marks
⋆⋆⋆⋆⋆

1. Discuss in detail about biodiversity. [16]

2. Explain gene Regulation in Eukaryotes. [16]

3. Explain kinetics of DNA renaturation. [16]

4. How many invertebrates genomes are sequences? [16]

5. How could you find genes by EST database? [16]

6. Where do you find genomic variation explain? [16]

7. Explain how SNP maps plays important role to predict the response to medicines.
[16]

8. What are the regulatory and legislative approaches to the control in human ge-
nomics? [16]

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Code No: RR412301 Set No. 3
IV B.Tech I Semester Regular Examinations, November 2007
GENOMICS AND PROTEOMICS
(Bio-Technology)
Time: 3 hours Max Marks: 80
Answer any FIVE Questions
All Questions carry equal marks
⋆⋆⋆⋆⋆

1. Discuss in detail about biodiversity. [16]

2. Explain gene Regulation in Eukaryotes. [16]

3. Explain kinetics of DNA renaturation. [16]

4. How could you compare genomes with new template method? [16]

5. Write short notes:

(a) EST
(b) cDNA. [8+8]

6. Discuss in detail about proteomics. [16]

7. Discuss in detail how positional cloning plays an important role in disease gene
identification. [16]

8. How could you explain drug design using known receptor structures? [16]

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Code No: RR412301 Set No. 4
IV B.Tech I Semester Regular Examinations, November 2007
GENOMICS AND PROTEOMICS
(Bio-Technology)
Time: 3 hours Max Marks: 80
Answer any FIVE Questions
All Questions carry equal marks
⋆⋆⋆⋆⋆

1. Write short notes

(a) Basal transcriptional factor

(b) Promoters [8+8]

2. Explain how chromatin structure plays important role in Eukaryotic gene regula-
tion. [16]

3. Explain kinetics of DNA renaturation. [16]

4. Discuss in detail how many microbe DNA are sequenced. [16]

5. Write short notes:

(a) Protein sequence data

(b) Sequence database search. [8+8]

6. Explain why every genome is different. [16]

7. What are the approache for identifying gene? [16]

8. How could you explain drug design using known receptor structures? [16]

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