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Complications list for Viral Hepatitis:

The list of complications that have been mentioned in various sources for Viral Hepatitis includes:

Arthritis-like problems (see Joint pain) Fulminant hepatitis B (see Liver symptoms) - very rare Chronic Hepatitis - i.e. becoming a carrier of the disease Chronic Hepatitis B Chronic Hepatitis C

URL: http://www.wrongdiagnosis.com/v/viral_hepatitis/complic.htm , June 23, 2010.


Complications of viral hepatitis include: Bleeding Chronic hepatitis Cirrhosis Encephalopathy: o Liver disease that causes confusion and excessive sleepiness Liver cancer Liver failure Malnutrition

Continue to Viral Hepatitis Underlying Cause

URL: http://www.freemd.com/viral-hepatitis/complications.htm

Complications 1) Persistant infection:Following acute infection, approximately 5% of infected individuals fail to eliminate the virus completely and become persistantly infected. Those who are at particular risk include: babies, young children immunocompromised patients males > females The virus persists in the hepatocytes and on-going liver damage occurs because of the host immune response against the infected liver cells. Chronic infection may take one of two forms: Chronic persistent Hepatitis - the virus persists, but there is minimal liver damage

Chronic Active Hepatitis - There is aggressive destruction of liver tissue and rapid progression to cirrhosis or liver failure. 2) Patients who become persistently infected are at risk of developing hepatocellular carcinoma (HCC).. HBV is thought to play a role in the development of this malignancy because: a) 80% of patients with HCC are carriers of hepatitis B. b) Virus DNA can be identified in hepatocellular carcinoma cells. c) Virus DNA can integrate into the host chromosome. 3) Fulminant Hepatitis Rare; accounts for 1% of infections.
URL: http://web.uct.ac.za/depts/mmi/jmoodie/dihep.html
Symptoms and Complications of Hepatitis A and B
Hepatitis A has an incubation period (the time between infection and first symptoms) of 2 to 6 weeks. Hepatitis B only shows itself after 2 to 6 months. Flu-like warning symptoms (called a prodrome) often appear about 3 to 10 days before liver symptoms arrive. Symptoms include low-grade fever, muscle aches, loss of appetite, nausea, vomiting, and fatigue. Smokers may find they suddenly dislike smoking. In hepatitis B, these symptoms may be accompanied by joint pains and skin eruptions resembling urticaria (hives). After this, the urine may darken and jaundice may appear. In jaundice, the skin and the whites of the eyes take on a yellow tint. The inflamed liver is not able to perform its usual metabolic functions so that a substance called bilirubin (a byproduct from old red blood cells that also causes bile to be yellow) builds up in the body. Bile is a fluid secreted by the liver that contains cholesterol, bile salts, and waste products such as bilirubin. Usually, you start to feel better when the jaundice arrives, even though you continue to look worse. The jaundice only lasts for about one week in hepatitis A infection. After that you start to recover and will generally feel and look yourself again within a month. Rarely, hepatitis A may come back briefly a month later, but won't last long. After recovering from hepatitis A, you're immune for life. With hepatitis B, the jaundice lasts for about two weeks. However, the hepatitis B infection doesn't always get cleared out of the system. If this happens, you will probably not have any symptoms, but you'll be a lifelong "carrier" and must take special precautions such as warning sexual partners. You may also suffer from chronic liver inflammation (chronic viral hepatitis) for the rest of your life. Chronic hepatitis B is most likely to occur in infants (around a 90% chance if infected in the first year of life) and least likely in adults (5% chance overall). It can lead to cirrhosis (scarring) of the liver. It also increases the risk of developing liver cancer.

URL: http://www.medbroadcast.com/condition_info_details.asp?disease_id=69,
reviewed: March 8, 2010

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What is the pathophysiology of hepatitis?

Answer: Although HCV can be found in multiple sites throughout the bodyincluding the liver, at a tangent blood mononuclear cells, dendritic cell, epithelium, and even the central diffident system, HCV replicates in the hepatocytes. However, it is ultimately hepatotoxic. Viral replication occurs through an RNA-dependent RNA polymerase process. Lymphocytes spot infected cells and initiate an immune response to control the virus. Viral clearance is associated near the development and doggedness of strong, virus-specific responses by cytotoxic T lymphocytes and T helper cell. Because of the rapid evolution of diverse quasispecies inwardly an infected person, even a brisk B cell (eg, antibody) response to hepatitis C have been not enough to clear theinfection, as the virus represents a "moving target" to the immune system. For the same apology, the progress in nouns of a vaccine to protect patients from an initial infection has be slow.7 Damage to the liver parenchyma is mediated by inflammatory cytokines. Persistent inflammatory peacekeeping troops activate stellate cell in the liver parenchyma and this results surrounded by various degree of hepatic fibrosis. Why some patients develop progressive fibrosis and eventually cirrhosis and others do not is unknown, but some predictors of progression have be identified, and include male sex, age at beginning of infection, and the use of alcohol. --HCV (Hep C) is notorious for cause chronic viral hepatitis. --The virus enters and injures hepatocytes --Chronic inflammatory response develops --Eventual progression to cirrhosis resulting within liver failure and departure Viral? The virus itself does not harm the liver, however, by sagging out there it cause an immune response that results in inflammatory change. The chronic inflammatory state is what damages the liver. So basically surrounded by the presence of the virus our body wages war on our liver, hurting it, slaughter it and turning it cirrhotic. in hepatitis, the liver cell get infected by virus. thus they swells up as there is inflammation. thus the bile ducts surrounded by between the cells get obstructed rasulting into rise of bilirubin in blood. disappear activities of hepaticcell also adds to it. thus jaundice occur The word hepatitis means - inflammation of the liver. This can be cause by a multitude of reasons: viral - the cell of the liver are attacked by a virus bacterial - the cells of the liver or the ducts of the portal system are irritated and subsequently infected for some intention, i.e. gall stones drug induced - whether licit or illicit, most drugs are metabolised and excreted by the liver. In roomy doses these can become toxic to the liver and hepatitis can occur. Your grill on pathophysiology should be more specific to what the potential cause of the hepatitis is however commonly, it is just the chief inflammation of the liver cells reducing the efficacy of the organ thereby potentially cause multiple problems. URL:

http://www.dcqna.com/diseases-conditions/21677-y51.html

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