Welcome To

Microbiology and Immunology 2100A Biology of Prokaryotes 2012

Information Flow

OWL site access via https://owl.uwo.ca

For assistance with OWL, contact the ITS Computer Support Centre By Webform: http://itshelp.uwo.ca By Phone: 519-661-3800 In Person: main floor right inside the front doors of the Support Services Building

OWL Course Tools

Home Announcements Syllabus (Course outline and information) Schedule (Calendar) Messages

OWL Course Tools

Lectures Lab information Lab Reports Prelab Talks

Lectures will be in pdf format or Power Point presentations

Course Schedule

Lectures

Monday and Wednesday 11:30 am 12:20 pm WSC 55 Tuesday, Wednesday or Thursday 2:30 to 5:30 pm Medical Sciences Building (MSB) 120 weekly

Laboratories

Instructors

Dr. Susan Koval, Course Coordinator Dental Science Building 3013A

Tel: 519-661-3439 Dr. Carole Creuzenet Dr. Tom Linn

Instructors are available via OWL messages, or by appointment

Sources of Wisdom

Instructors Textbook Brock Biology of Microorganisms, by M.T. Madigan, J.M. Martinko, D.A. Stahl and D.P. Clark. 13th edition. 2012 Benjamin Cummings
2 copies in the Taylor Library on 2 h reserve

Lab Manual Microbiology: Laboratory Theory and Application, Brief, 2nd edition, M.J. Leboffe and B.E. Pierce, Morton Publishing, 2012. Additional microbiology textbooks, for use in writing lab reports, are on 2 h reserve in the Taylor library

Course readings will be assigned from the textbook by each instructor The readings expand the concepts discussed in the lectures

Evaluation
Component
Midterm test Laboratory Final exam

% of Final Mark
25 30 45

Midterm test: Friday October 26, 2012, 7:30 to 9 pm in Labatt Health Sciences Building, room 40

Format of exams

Midterm test and final exam will consist of multiple choice questions from lectures and assigned readings Course work for the midterm test includes lectures to the end of the Metabolism section Final exam will be cumulative, with emphasis on the second half of the course

Deadlines and Ethical Issues

Described in detail in the Syllabus

Absence from tests and exams Absence from laboratory periods

Very important to read!

Course Strategies/Philosophy

MicroImm 2100A is an entry-level course in bacteriology it provides background information for advanced courses, and thus will encompass details as well as concepts assumes a fundamental working knowledge of biology and developing concepts of biochemistry

Our Responsibilities and Expectations

Teach the fundamental concepts of bacteriology via lectures and laboratories Be available for consultation We expect students to Attend lectures and laboratories Come prepared Do the course readings Work hard instructors are aware that many students in this course have a variety of career goals in mind. Skills acquired in this course can be used in other settings, not just in a microbiology environment

Your Responsibilities and Expectations

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Laboratory Schedule

Laboratories are weekly No laboratory practical the week of September 10th time will be used to discuss topics related to microbiology labs: biosafety and the writing of laboratory reports Attendance is noted, as is punctuality Reserve the three hour time slot in your schedule

Laboratory Session week of September 10

MSB 120 at 2:30 pm the following topics will be discussed Laboratory procedures and safety rules Biosafety Biohazards Guidelines for writing laboratory reports

Please READ these two files: Laboratory Guidelines Guidelines for Writing Laboratory Reports

Course Description in the Academic Calendar

This course examines the fundamental aspects of the structure, physiology, genetics and phylogenetic relationships of the Bacteria and Archaea. Examples of medically and environmentally important organisms are presented.

Relevance of microbes to health, industry and the environment

Borrelia burgdorferi

Legionella pneumophila

Pathways of Discovery in Microbiology

Dr Susan Kovals concept map for 2100A

Taxonomy: who are we looking at?

Metabolism: how do prokaryotes generate energy?

The prokaryotic cell: structure and function

Environmental effects on growth: Some like it hot, some dont !

Lectures by Drs. Creuzenet and Linn

Dr Tom LINNs concept map for 2100A

BACTERIAL GROWTH
Cell Division
Bacterial Population Growth Control of Bacterial Growth

GENE EXPRESSION
Transcription of Bacterial Genes
Basic Mechanisms of Regulating Transcription Genomics

Bacterial Empire Strikes Back (Drug Resistance)

(Genes, RNA, Proteins, Metabolites, Interactions on an Organism Scale)

Dr Carole CREUZENETs concept map for 2100A

Food- and water- borne bacterial diseases

Bacterial genetics

Mechanisms of gene transfer/mutations Shaping evolution

Bacterial pathogens and associated diseases Concepts/mechanisms Origin of toxins/virulence features

Transfer of virulence traits

R.R. Colwell (Past President of the American Society for Microbiology)

Microorganisms are what keeps life going on the planet. There needs to be an understanding that microorganisms are not just pathogens. For every pathogen, there are large numbers of microorganisms carrying out protective activities that keep the cycle of nature going".

From: The Microbial World: Foundation of the Biosphere. 1997. American Academy of Microbiology

Enjoy the course!